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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F_RS00170 [old locus tags: SPN23F00280 SPN23F_00280 ]
  • pan locus tag?: PNEUPAN000390000
  • symbol: SPN23F_RS00170
  • pan gene symbol?: —
  • synonym:
  • product: ImmA/IrrE family metallo-endopeptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F_RS00170 [old locus tags: SPN23F00280 SPN23F_00280 ]
  • symbol: SPN23F_RS00170
  • product: ImmA/IrrE family metallo-endopeptidase
  • replicon: chromosome
  • strand: -
  • coordinates: 28691..29071
  • length: 381
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_011900 (28691..29071) NCBI
  • BioCyc: SPN23F_RS00170 BioCyc
  • MicrobesOnline: see SPN23F00280
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGACACTCGCTAAACTCTGCGAAGAATATCAAGTAGAACTTTGTCTCTTCGACGGTTCA
    AACTGGCACAATAGCGGTTTCTACAATCCAGACACAAACGTGCTCGCTATTGACCACAAC
    TTGACTCCTGAACAACAAATCCAAGTCGCCCTACACGAACTTGGACACAAAGACCACACA
    CGCTCAGAGCACCAGAACGCCCGTCTACGCTGTGAAAACGAAGCTGATAGGAATATGATC
    CATCATCTCGTAAAAGACGCTCTAGAAAACTTAGACGACCCCACAGAGTTTGATTACCTC
    AAATTCATGTCTTACTACAATCTAAAAACCATGACAAATGAAATCATGGTTAAAGAAGAG
    TATTTAGCATTAGTAAATTAA
    60
    120
    180
    240
    300
    360
    381

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F_RS00170 [old locus tags: SPN23F00280 SPN23F_00280 ]
  • symbol: SPN23F_RS00170
  • description: ImmA/IrrE family metallo-endopeptidase
  • length: 126
  • theoretical pI: 4.67306
  • theoretical MW: 14826.5
  • GRAVY: -0.646825

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SPN23F00280
  • PFAM:
    no clan defined DUF6782; Putative metallopeptidase family (DUF6782) (PF20573; HMM-score: 31.6)
    Peptidase_MA (CL0126) Peptidase_M78; IrrE N-terminal-like domain (PF06114; HMM-score: 30)
    and 1 more
    no clan defined Calmod_bind_C; Calmodulin binding protein C-terminal domain (PF20452; HMM-score: 13.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8562
    • Cytoplasmic Membrane Score: 0.0023
    • Cell wall & surface Score: 0.0007
    • Extracellular Score: 0.1407
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004321
    • TAT(Tat/SPI): 0.000124
    • LIPO(Sec/SPII): 0.000858
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000170931 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPEQQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKFMSYYNLKTMTNEIMVKEEYLALVN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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