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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-FEB-2025

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F_RS00180 [old locus tags: SPN23F00300 SPN23F_00300 ]
  • pan locus tag?: PNEUPAN000394000
  • symbol: SPN23F_RS00180
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F_RS00180 [old locus tags: SPN23F00300 SPN23F_00300 ]
  • symbol: SPN23F_RS00180
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 29347..29580
  • length: 234
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_011900 (29347..29580) NCBI
  • BioCyc: SPN23F_RS00180 BioCyc
  • MicrobesOnline: see SPN23F00300
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGACTATCACTATCAACTTCACAGAAAAAAATTCCTACATTACGGACTACCTAAACAAA
    CACGGTATCGACACAACGACCATGGATTTTGACGACTTCATGGCACTCATGGAAGATATC
    GAAGACGCACGAGCAGCCGACCAAGCCTATATGGAGTATTTAGCCGACCCAGCTACTTAT
    ACCATGGATGAGGTCTTGGATGAACTAGGACTAACTCGAGAGGATATTGCTTAA
    60
    120
    180
    234

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPN23F_RS00180 [old locus tags: SPN23F00300 SPN23F_00300 ]
  • symbol: SPN23F_RS00180
  • description: hypothetical protein
  • length: 77
  • theoretical pI: 3.58022
  • theoretical MW: 8858.74
  • GRAVY: -0.376623

Function[edit | edit source]

  • TIGRFAM:
    peptidyl-prolyl isomerase, gliding motility-associated (TIGR03516; HMM-score: 12.3)
  • TheSEED: see SPN23F00300
  • PFAM:
    Met_repress (CL0057) DUF6290; Family of unknown function (DUF6290) (PF19807; HMM-score: 20)
    and 5 more
    Phage_TACs (CL0567) Phage_TAC_8; Phage tail assembly chaperone protein Gp14 ()A118 (PF10666; HMM-score: 15.7)
    GlnB-like (CL0089) Rhomboid_N; Cytoplasmic N-terminal domain of rhomboid serine protease (PF12122; HMM-score: 13.8)
    no clan defined Chlamy_scaf; Chlamydia-phage Chp2 scaffold (Chlamy_scaf) (PF09675; HMM-score: 13)
    Ish1; Putative nuclear envelope organisation protein (PF10281; HMM-score: 12.7)
    Cupin (CL0029) JmjN; jmjN domain (PF02375; HMM-score: 12)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9785
    • Cytoplasmic Membrane Score: 0.0005
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0207
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001916
    • TAT(Tat/SPI): 0.000118
    • LIPO(Sec/SPII): 0.000213
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000156419 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDARAADQAYMEYLADPATYTMDEVLDELGLTREDIA

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]