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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 11-FEB-2025
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae ATCC 700669
- locus tag: SPN23F_RS01875 [old locus tags: SPN23F03640 SPN23F_03640 ]
- pan locus tag?: PNEUPAN001232000
- symbol: cbpG
- pan gene symbol?: cbpG
- synonym:
- product: choline-binding protein CbpG
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPN23F_RS01875 [old locus tags: SPN23F03640 SPN23F_03640 ]
- symbol: cbpG
- product: choline-binding protein CbpG
- replicon: chromosome
- strand: +
- coordinates: 352443..353264
- length: 822
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_011900 (352443..353264) NCBI
- BioCyc: SPN23F_RS01875 BioCyc
- MicrobesOnline: see SPN23F03640
- PneumoBrowse for strain D39V: SPV_0356 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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721
781ATGAATGTAGAAGGGAGGGGAAGTGCGAATTTTATTAAAGATAATGTGTTAATTACAGCG
GCTCACAACTACTACAGACATGACTATGGGAAAGAAGCGGATGATATTTATGTTCTTCCG
GCTGTTAGTCCAAGTCAAGAACTATTTGGAAAGATCAAAGTAAAGGAAGTTCGTTATTTG
AAGGAATTTAGAAATTTAAATTCTAAGAATGCAAGGGAATATGACTTGGCTTTATTAATT
CTAGAAGAGCCCATTGGTGCAAAATTAGGGACTTTGGGTCTTCCTACTAGTCAAAAAAAT
TTGACAGGAATAACTGTGACTATCACAGGCTATCTATCATATAATTTTAAAATTCATCAA
ATGTATACAGATAAAAAACAAGTTTTAAGTGATGATGGCATGTTCTTGGATTACCAAGTT
GATACTTTAGAGGGGTCTAGTGGATCTGCAGTTTATGATGCTAGTCACCGCGTAGTAGGA
GTGCATACTTTAGGAGATGGAGCTAATCAAATTAACAGTGCAGTTAAATTAAATGAACGA
AATTTGCCATTTATTTATTCGGTTCTTAAAGGTTACTCTCTTGAAGGATGGAAGAAAATA
AATGGTAGTTGGTACTATTATAGACAACATGATAAACAAACGGGTTGGCAGGAGATAAAT
GATACTTGGTATTATTTAGACAGTTCCGGTAAGATGCTTACAGATTGGCAAAAAGTAAAT
GGAAAATGGTATTATCTCAATTCAAATAGAGCAATGGTTACAGGTAGCCAAACTATCGAT
GGTAAAGTTTATAACTTCGCTTCATCTGGTGAGTGGATTTGA60
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822
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPN23F_RS01875 [old locus tags: SPN23F03640 SPN23F_03640 ]
- symbol: CbpG
- description: choline-binding protein CbpG
- length: 273
- theoretical pI: 7.82373
- theoretical MW: 31072.7
- GRAVY: -0.504396
⊟Function[edit | edit source]
- TIGRFAM: glucan-binding repeat (TIGR04035; HMM-score: 46.7)and 1 moreRegulatory functions Protein interactions exported signaling peptide, YydF/SAG_2028 family (TIGR04077; HMM-score: 9.1)
- TheSEED: see SPN23F03640
- PFAM: Choline_binding (CL0694) Choline_bind_3; Choline-binding repeat (PF19127; HMM-score: 70.3)and 6 moreCholine_bind_1; Putative cell wall binding repeat (PF01473; HMM-score: 56.1)Peptidase_PA (CL0124) Trypsin; Trypsin (PF00089; HMM-score: 34.9)Trypsin_2; Trypsin-like peptidase domain (PF13365; HMM-score: 33.6)Peptidase_S39; Peptidase S39 (PF02122; HMM-score: 16.7)Peptidase_S32; Equine arteritis virus serine endopeptidase S32 (PF05579; HMM-score: 11.6)Choline_binding (CL0694) Choline_bind_2; Choline-binding repeat (PF19085; HMM-score: 7.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- DeepLocPro: Extracellular
- Cytoplasmic Score: 0.0009
- Cytoplasmic Membrane Score: 0.0002
- Cell wall & surface Score: 0.0064
- Extracellular Score: 0.9925
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.013271
- TAT(Tat/SPI): 0.001099
- LIPO(Sec/SPII): 0.005373
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_001100142 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKNAREYDLALLILEEPIGAKLGTLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSAVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQEINDTWYYLDSSGKMLTDWQKVNGKWYYLNSNRAMVTGSQTIDGKVYNFASSGEWI
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0356 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
B Mann, C Orihuela, J Antikainen, G Gao, J Sublett, T K Korhonen, E Tuomanen
Multifunctional role of choline binding protein G in pneumococcal pathogenesis.
Infect Immun: 2006, 74(2);821-9
[PubMed:16428724] [WorldCat.org] [DOI] (P p)