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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
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INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 700669
  • locus tag: SPN23F_RS04485 [old locus tags: SPN23F08800 SPN23F_08800 ]
  • pan locus tag?: PNEUPAN001972000
  • symbol: SPN23F_RS04485
  • pan gene symbol?: comEC
  • synonym: celB
  • product: DNA internalization-related competence protein ComEC/Rec2

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN23F_RS04485 [old locus tags: SPN23F08800 SPN23F_08800 ]
  • symbol: SPN23F_RS04485
  • product: DNA internalization-related competence protein ComEC/Rec2
  • replicon: chromosome
  • strand: +
  • coordinates: 854462..856702
  • length: 2241
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTT
    TGGCTTTATTACGCTATTTTCTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTG
    CTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTGGTAAAGTTCTAATAATTTGC
    GGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
    CTGGCGGATTCTGTTGAAAGGGTACGGATTTTACCTGATACTATTAAGGTTAATGGTGAT
    AGTCTATCCTTTCGTGGCAAGTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAG
    TCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACCTGCATGAGATAGGACTAGAA
    GGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
    CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAAAAATCCAGTCACTTCAAAAG
    ATTGGCAGTTGGGATATAGGAGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGG
    ATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGACAGGACTCTTGCTGGGATAT
    CTGAACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
    TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTG
    CGATTGGGCTTGACCCAAGAAAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTAT
    GCGGGACTAATTGGATTTTCAGCATCGGTTATTCGCAGTCTCTTGCAAAAGCTACTGGCT
    CAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
    ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTG
    ACCATGACCAGCAAAGAAGGGGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATC
    TCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGGAATTTCAACCTTGGTCTATC
    CTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
    TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTA
    GAGGGCATTATTCGCTTGGTCTCGCAGGTGGCAAGGAGACCGCTTGTCTTTGGTCAACCC
    AACGCATGGCTTTTAATCTTATTGTTAATTTCCTTGGCTTTGGTCTATGATTTGAGGAAA
    AACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
    TATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTA
    CGGGATGTAACTGGGAAAACCATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAG
    AAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATGCACAGAGAAGCTTGATACCC
    TATCTTAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTGATTTTGACAAATACGGACAAG
    GAACATGTCGGAGATTTGTTAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTAGTA
    TCAAAAGGCAGTTTGAAGCAGAAGCAATTTGTGGTAGAACTACAGGCGACTCAAACAAAG
    GTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTGGAAGTCAGTTAGAAGTTCTA
    TCCCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
    TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTG
    AAGCACTATCCAGACTTGAAAGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAA
    TCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGCTTACTCTTATCTCAGTTGGA
    AAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
    AGCAAAGTTTACCGAACTGACCAGCAAGGAGCTATACGGTTTAAAGGTTGGAATAGTTGG
    AAAATCGAAAGTGTTCGATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2241

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN23F_RS04485 [old locus tags: SPN23F08800 SPN23F_08800 ]
  • symbol: SPN23F_RS04485
  • description: DNA internalization-related competence protein ComEC/Rec2
  • length: 746
  • theoretical pI: 9.80236
  • theoretical MW: 84588.6
  • GRAVY: 0.184584

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes DNA transformation DNA internalization-related competence protein ComEC/Rec2 (TIGR00361; HMM-score: 254)
    and 1 more
    Unknown function General ComEC/Rec2-related protein (TIGR00360; HMM-score: 48.8)
  • TheSEED: see SPN23F08800
  • PFAM:
    no clan defined Competence; Competence protein (PF03772; HMM-score: 115.8)
    and 2 more
    DUF4131; Domain of unknown function (DUF4131) (PF13567; HMM-score: 44.1)
    Metallo-HOrase (CL0381) Lactamase_B; Metallo-beta-lactamase superfamily (PF00753; HMM-score: 30.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00178
    • TAT(Tat/SPI): 0.000425
    • LIPO(Sec/SPII): 0.071335
  • predicted transmembrane helices (TMHMM): 9

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000942392 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAYLKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGYLNTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLIGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLISLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDLLEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGWNSWKIESVR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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