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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 05-APR-2025

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN994039
  • locus tag: SPN994039_RS09700 [old locus tag: SPN994039_17660 ]
  • pan locus tag?: PNEUPAN003647000
  • symbol: SPN994039_RS09700
  • pan gene symbol?: macB_2
  • synonym:
  • product: ABC transporter permease

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPN994039_RS09700 [old locus tag: SPN994039_17660 ]
  • symbol: SPN994039_RS09700
  • product: ABC transporter permease
  • replicon: chromosome
  • strand: -
  • coordinates: 1791226..1792188
  • length: 963
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_021005 (1791226..1792188) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1824 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAACATGTCAAATATTACTATAGATGGGCAAGAAATGGATCTGAGTCAAACGATGCCT
    TCTTATGCTCAAGTAGTGAGTCTTTCTGAGGATACAAGCATCTCTGTTAGTAGTAATGAG
    ACGGACAAAGTGTTGGCTGGATCCCTCTATACTGATACAAATGAACAGGGATTAACGATT
    CCAAGCAGTTTACTAAAAAATTGGAATGAACAGACAGGAAAAAATTTGACAGCTAATGAT
    CTTATTGGCAAATCAGTCTCAGCCAGCATTGTAGAAAGTGCTGCCGAAGCTAGTAAGATT
    GCTCAATTTCAAACGAAGATTGTACGTGTAATCAATGATGAAGATGACATGGAGGACAGC
    AACAGTTTCATGCTGTCTCATCAAATGGAAACGATTTTGAAAGAGGCTGGATTTATGAAA
    GCTGTATCTTATTTTATCTTGGAATTCAAAGATCCATCACAGACAAAAGTAGTAACAGAA
    GAATTACAGAAAAATAAGAAGTATACTGTGCTTTCTCAACAGAGAGTTCTTGATATTGTG
    ATTACCTTTATTCGTGTTATTCAGGGATTATTGATTGTGCTTTCATCACAAGCTATTGTG
    GTAGCAGCGGTTATGATTGGTATTATTATTTACATCAATATCATGCAACGTTCCAAGGAA
    ATAGGTGTCATGAAGGCAGTTGGTTATCAGAATCGTGATGTCAAAGGAATTTTTATTTAC
    GAGGTTATCTGGATTGTAGGCATCGCCTTGCTGCTGGCATTTTTGGTTGCACAAGGGGTG
    GGAAGTTTGGCGAATGCGATTGTAAGTCACTTTTACCCATCCATCACTAAGGTTTTTGAA
    TTAAATCTTTTATCTGTTTTAGGAACTCTAGTTTTCGCTCTATTACTTGGTTATGTCTCA
    GCCTACTTCCCGGCGCGTAAGATTAGTAAAATGGACCCTGTAGAATCGCTACGCTATGAA
    TAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    963

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPN994039_RS09700 [old locus tag: SPN994039_17660 ]
  • symbol: SPN994039_RS09700
  • description: ABC transporter permease
  • length: 320
  • theoretical pI: 4.77373
  • theoretical MW: 35348.8
  • GRAVY: 0.269062

Function[edit | edit source]

  • TIGRFAM:
    acidobacterial duplicated orphan permease (TIGR03434; HMM-score: 53.3)
    and 7 more
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein, LolC/E family (TIGR02212; HMM-score: 40.8)
    Cellular processes Cellular processes Cell division putative protein insertion permease FtsX (TIGR00439; HMM-score: 20.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking putative protein insertion permease FtsX (TIGR00439; HMM-score: 20.5)
    Metabolism Transport and binding proteins Other ABC exporter transmembrane subunit, DevC protein (TIGR01185; HMM-score: 17.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein LolE (TIGR02213; HMM-score: 17.3)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter permease LptF (TIGR04407; HMM-score: 15.8)
    Metabolism Transport and binding proteins Other LPS export ABC transporter permease LptF (TIGR04407; HMM-score: 15.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    BPD_transp_1 (CL0404) FtsX; FtsX-like permease family (PF02687; HMM-score: 62.3)
    and 2 more
    no clan defined Peptidase_M13_N; Peptidase family M13 (PF05649; HMM-score: 14.3)
    Tudor (CL0049) Tudor_3; DNA repair protein Crb2 Tudor domain (PF18115; HMM-score: 13.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9993
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0006
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.034429
    • TAT(Tat/SPI): 0.001887
    • LIPO(Sec/SPII): 0.001969
  • predicted transmembrane helices (TMHMM): 3

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001057330 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNMSNITIDGQEMDLSQTMPSYAQVVSLSEDTSISVSSNETDKVLAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQFQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFMKAVSYFILEFKDPSQTKVVTEELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIGVMKAVGYQNRDVKGIFIYEVIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]