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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 27-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_00639 [new locus tag: SPNA45_RS03685 ]
  • pan locus tag?: PNEUPAN002968000
  • symbol: SPNA45_00639
  • pan gene symbol?: cshA
  • synonym:
  • product: DEAD box helicase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_00639 [new locus tag: SPNA45_RS03685 ]
  • symbol: SPNA45_00639
  • product: DEAD box helicase family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 640268..641365
  • length: 1098
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGCTTAACATGGGCTTCCTTGAAGACATCGAAGCCATTATTTCCCGTGTACCTGAGAAC
    CGTCAAACTTTGCTTTTCTCAGCAACTATGCCAGATGCCATCAAACGTATCGGTGTTCAG
    TTTATGAAAGCCCCTGAACATGTCAAGATTGCGGCTAAGGAATTGACAACAGAATTGGTT
    GACCAGTACTATATCCGTGTTAAGGAACAAGAAAAATTTGACACCATGACTCGTCTCATG
    GATGTGGCACAACCAGAACTCGCTATTATATTTGGTCGTACCAAACGCCGTGTGGATGAA
    TTGACTCGTGGTTTGAAAATTCGTGGCTTCCGTGCAGAAGGAATTCATGGCGACCTAGAC
    CAAAACAAACGTCTTCGTGTCCTTCGTGACTTTAAAAATGGCAATCTTGATGTTTTGGTT
    GCGACAGACGTTGCAGCGCGTGGTTTGGATATTTCAGGTGTGACCCATGTCTACAACTAC
    GATATTCCACAAGATCCTGAGAGTTATGTTCACCGTATCGGTCGTACAGGTCGTGCTGGT
    AAGTCAGGTCAATCTATTACTTTTGTTGCTCCAAACGAAATGGGTTACCTTCAAATCATT
    GAAAACTTGACTAAGAAACGCATGAAAGGTCTCAAACCTGCAAGTGTAGAAGAATCCTTC
    CAATCAAAAAAACAGGTAGCTCTCAAGAAAATCGAACGTGATTTTGCAGATGAAACCATT
    CGTGCCAACTTTGAGAAATTTGGTAAGGATGCTCGCAAATTGGCTGCTGAGTTTACTCCA
    GAAGAATTGGCAATGTATATCTTGAGTCTGACAGTCCAAGACCCAGATAGCCTTCCAGAA
    GTGGAGATTGCACGTGAAAAACCACTACCGTTTAAACCATCAGGTAATGGTTTCGGTGGT
    AAAGCTAAGGGAGGTCGTGGAGGCCGTCGTGGGGACGACCGTCGAGAGCGTGATCGCCGT
    GATGAGTTCAAAAAAGGAAGTCGTGGCAACGATCGTTTTGATAAGGAAAAACGTTACCGT
    AAGGATAATAAAAAACCACGCAATACTTTAAGCGAAAAGCAAACAGGCTTTGTTATTCGT
    AACAAAGGCGATAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1098

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_00639 [new locus tag: SPNA45_RS03685 ]
  • symbol: SPNA45_00639
  • description: DEAD box helicase family protein
  • length: 365
  • theoretical pI: 10.4066
  • theoretical MW: 41650.3
  • GRAVY: -0.778356

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase RecQ (TIGR01389; EC 3.6.4.12; HMM-score: 68.4)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase, RecQ family (TIGR00614; EC 3.6.4.12; HMM-score: 63.6)
    and 8 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit B (TIGR00631; EC 3.1.25.-; HMM-score: 38.1)
    DEXH box helicase, DNA ligase-associated (TIGR04121; EC 3.6.4.-; HMM-score: 24.7)
    CRISPR-associated helicase Cas3 (TIGR01587; HMM-score: 22.3)
    DNA phosphorothioation system restriction enzyme (TIGR04095; HMM-score: 21.9)
    helicase/secretion neighborhood putative DEAH-box helicase (TIGR03817; HMM-score: 18.7)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase RecG (TIGR00643; EC 3.6.4.12; HMM-score: 17.7)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair transcription-repair coupling factor (TIGR00580; EC 3.6.1.-; HMM-score: 16.9)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking accessory Sec system translocase SecA2 (TIGR03714; HMM-score: 12.1)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    P-loop_NTPase (CL0023) Helicase_C; Helicase conserved C-terminal domain (PF00271; HMM-score: 108.4)
    and 1 more
    DEAD; DEAD/DEAH box helicase (PF00270; HMM-score: 19.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.94
    • Cytoplasmic Membrane Score: 2.06
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002425
    • TAT(Tat/SPI): 0.000793
    • LIPO(Sec/SPII): 0.000399
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCM07927 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLNMGFLEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYYIRVKEQEKFDTMTRLMDVAQPELAIIFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQNKRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAGKSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADETIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGNGFGGKAKGGRGGRRGDDRRERDRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNTLSEKQTGFVIRNKGDK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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