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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 27-FEB-2015
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae SPNA45
- locus tag: SPNA45_01384 [new locus tag: SPNA45_RS07775 ]
- pan locus tag?: PNEUPAN002239000
- symbol: rex
- pan gene symbol?: rex
- synonym:
- product: putative redox-sensing transcriptional repressor
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPNA45_01384 [new locus tag: SPNA45_RS07775 ]
- symbol: rex
- product: putative redox-sensing transcriptional repressor
- replicon: chromosome
- strand: -
- coordinates: 1388816..1389241
- length: 426
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: HE983624 (1388816..1389241) NCBI
- BioCyc: see SPNA45_RS07775
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0976 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421ATGACATTTTTTGCCGATTTGCTCAATGACAACTCTATTACCAATGTCATGCTGGTTGGT
ATTGGAAATATGGGCCATGCCCTTCTCCACTACCGCTTCCACGAACGTAACAAGATGAAG
ATTATCATGGCCTTTGACCTAGACGACCATCCTGAAGTCGGTACCCAAACTCCTGACGGG
ATTCCCATTTACGGGATTTCTCAGATCAAGGATAAAATCAAGGATGCTGATGTGAAGACT
GCTATCCTAACTGTTCCCAGCGTCAAGTCACAAGAGGTTGCTAATCTCTTGGTTGATGCT
GGTGTGAAAGGAATTCTCAGTTTTTCACCAGTCCATCTGCATTTACCAAAAGACGTGGTC
GTTCAGTATGTCGATTTGACAAGTGAACTCCAAACCCTCCTCTACTTCATGCGAAAAGAG
GATTAG60
120
180
240
300
360
420
426
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPNA45_01384 [new locus tag: SPNA45_RS07775 ]
- symbol: Rex
- description: putative redox-sensing transcriptional repressor
- length: 141
- theoretical pI: 5.90173
- theoretical MW: 15779.2
- GRAVY: 0.0531915
⊟Function[edit | edit source]
- TIGRFAM: undecaprenyl-phosphate glucose phosphotransferase (TIGR03023; EC 2.7.8.-; HMM-score: 17.1)exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (TIGR03025; HMM-score: 13.8)and 1 moreEnergy metabolism Sugars inositol 2-dehydrogenase (TIGR04380; EC 1.1.1.18; HMM-score: 12.6)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: NADP_Rossmann (CL0063) CoA_binding; CoA binding domain (PF02629; HMM-score: 90.5)and 1 moreno clan defined Plug_translocon; Plug domain of Sec61p (PF10559; HMM-score: 11.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
- genes regulated by Rex*, TF important in Energy metabolism: in TIGR4
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001962
- TAT(Tat/SPI): 0.000257
- LIPO(Sec/SPII): 0.00035
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: CCM08669 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MTFFADLLNDNSITNVMLVGIGNMGHALLHYRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- data available for TIGR4
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0976 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Muhammad Afzal, Sulman Shafeeq, Oscar P Kuipers
NADH-Mediated Gene Expression in Streptococcus pneumoniae and Role of Rex as a Transcriptional Repressor of the Rex-Regulon.
Front Microbiol: 2018, 9;1300
[PubMed:29971050] [WorldCat.org] [DOI] (P e)