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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 27-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_01676 [new locus tag: SPNA45_RS09380 ]
  • pan locus tag?: PNEUPAN001209000
  • symbol: SPNA45_01676
  • pan gene symbol?: mapZ
  • synonym:
  • product: putative membrane protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_01676 [new locus tag: SPNA45_RS09380 ]
  • symbol: SPNA45_01676
  • product: putative membrane protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1703462..1704832
  • length: 1371
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGAGTAAAAAAAGACGAAATCGTCATAAAAAAGAAGGTCAAGAACCGCAATTTGATTTT
    GATGAAGCAAAAGAGCTAACAGTTGGTCAAGCTATTCGTAAAAATGAAGAAGTGGAAGCA
    GGAGTCTTGCCTGAGGATTCCATTTTGGACAAGTATGTTAAGCAACACAGAGATGAAATT
    GAGGCGGATAAGTTTGCGACTCGTCAATACAAAAAAGAGGAGTTCGTTGAAACTCAGAGT
    CTGGATGATTTAATTCAAGAGATGCGTGAGGCTGTAGAGAAGTCAGAAGCTTCTTCGGAG
    GAAGTTCCATCTTCTGAAGACATCTTACTACCCTTGCCTCTGGACGATGAGGAGCAAGGC
    TTGGATCCTCTATTGCTAGATGATGAAAATCCAACAGAAATGACTGAAGAAGTGGAAGAG
    GAGCAAAACCTTTCTCGTCTGGATCAAGAGGACTCAGAAAAGAAAAGTAAAAAAGGCTTT
    ATTTTGACCGTTTTGGCGCTTGTATCAGTAATTATTTGTGTCAGTGCTTATTATGTCTAC
    CGTCAAGTGGCTCGTTCGACTAAGGAAATTGAAACTTCTCAATCAACTACAGCCAATCAA
    TCGGATGTGGATGATTTTAATACACTTTATGACGCCTTTTACACAGATAGCAATAAAACG
    GCTTTGAAAAATAGCCAGTTTGATAAACTGAGTCAACTCAAGACTTTACTTGATAAGCTG
    GAAGGTAGTCGTGAACATACGCTTGCCAAATCTAAATATGATAGTCTAGCAACGCAAATC
    AAGGCTATTCAAGATGTCAATGCTCAATTTGAGAAACCAGCTATTGTGGATGGTGTGTTG
    GATACCAATGCCAAAGCCAAATCGGATGCTAAATTTACAGATATTAAAACTGGAAATACG
    GAGCTTGATAAAGTGCTAGATAAGGCTATCAGTCTTGGTAAGAGCCAGCAAACAAGTACT
    TCTAGCTCAAGTTCAAGTCAAGCAAGTTCAAATACGACTAGTGAGCCAAAACCAAGTAGT
    TCAAATGAGACTAGAAGTAGTCGCAGTGAAGTCAATATGGGTCTCTCGAGTGCAGGGGTT
    GCTGTTCAAAGAAGTGCCAGTCGTGTTGCCTATAATCAGTCTGCTATTGATGATAGTAAT
    AACTCTGCCTGGGATTTTGCGGATGGTGTCTTGGAACAAATTCTAGCGACTTCACGTTCA
    CGTGGCTATATCACTGGAGACCAATATATCCTTGAACGTGTCAATATCGTTAACGGCAAT
    GGTTATTACAACCTCTATAAGCCAGATGGAACCTATCTCTTTACCCTTAACTGTAAGACA
    GGCTACTTTGTCGGAAATGGCGCTGGTCATGCGGATGACTTGGACTACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1371

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_01676 [new locus tag: SPNA45_RS09380 ]
  • symbol: SPNA45_01676
  • description: putative membrane protein
  • length: 456
  • theoretical pI: 4.39322
  • theoretical MW: 50776.4
  • GRAVY: -0.755482

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined MapZ_EC1; MapZ extracellular domain 1 (PF18041; HMM-score: 114.5)
    MapZ_C2; MapZ extracellular C-terminal domain 2 (PF18708; HMM-score: 106.4)
    and 8 more
    DUF6550; Family of unknown function (DUF6550) (PF20187; HMM-score: 18.3)
    TPR (CL0020) DUF6377; Domain of unknown function (DUF6377) (PF19904; HMM-score: 17.7)
    RNase_H (CL0219) DDE_Tnp_IS240; DDE domain (PF13610; HMM-score: 13.2)
    HTH (CL0123) Trans_reg_C; Transcriptional regulatory protein, C terminal (PF00486; HMM-score: 13)
    no clan defined Glycophorin_A; Glycophorin A (PF01102; HMM-score: 12.4)
    Otopetrin; Otopetrin (PF03189; HMM-score: 11.5)
    DUF3169; Protein of unknown function (DUF3169) (PF11368; HMM-score: 11.2)
    Vpu; Vpu protein (PF00558; HMM-score: 8.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9825
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.0169
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005693
    • TAT(Tat/SPI): 0.000721
    • LIPO(Sec/SPII): 0.000826
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCM08961 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLPEDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEVPSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGFILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSNKTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIVDGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGHADDLDY

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Aurore Fleurie, Christian Lesterlin, Sylvie Manuse, Chao Zhao, Caroline Cluzel, Jean-Pierre Lavergne, Mirita Franz-Wachtel, Boris Macek, Christophe Combet, Erkin Kuru, Michael S VanNieuwenhze, Yves V Brun, David Sherratt, Christophe Grangeasse
MapZ marks the division sites and positions FtsZ rings in Streptococcus pneumoniae.
Nature: 2014, 516(7530);259-262
[PubMed:25470041] [WorldCat.org] [DOI] (I p)

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