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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV200
  • locus tag: SPNINV200_RS04825 [old locus tag: SPNINV200_09010 ]
  • pan locus tag?: PNEUPAN002009000
  • symbol: prsA
  • pan gene symbol?: prsA
  • synonym:
  • product: peptidylprolyl isomerase PrsA

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS, pseudogene
  • locus tag: SPNINV200_RS04825 [old locus tag: SPNINV200_09010 ]
  • symbol: prsA
  • product: peptidylprolyl isomerase PrsA
  • replicon: chromosome
  • strand: +
  • coordinates: 910987..911927
  • length: 941
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_017593 (910987..911927) NCBI
  • BioCyc: SPNINV200_RS04825 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0868 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGAAGAAAAAATTATTGGCAGGTGCCATCACACTATTATCAGTAGCAACTTTAGCAGCT
    TGTTCGAAAGGGTCAGAAGGTGCAGACCTTATCAGCATGAAAGGGGATGTCATTACAGAA
    CATCAATTTTATGAGCAAGTGAAAAGCAACCCTTCAGCCCAACAAGTCTTGTTAAATATG
    ACCATCCAAAAAGTTTTTGAAAAACAATATGGCTCAGAGCTTGATGATAAAGAGGTTGAT
    GATACTATTGCCGAAGAAAAAAACAATATGGCGAAAACTACCAACGTGTCTTGTCACAAG
    CAGGTATGACTCTTGAAACACGTAAAGCTCAAATTCGTACAAGTAAATTAGTTGAGTTGG
    CAGTTAAGAAGGTAGCAGAAGCTGAATTGACAGATGAAGCCTATAAGAAAGCCTTTGATG
    AGTACACTCCAGATGTAACGGCTCAAATCATCCGTCTTAATAATGAAGATAAGGCCAAAG
    AAGTTCTCGAAAAAGCCAAGGCAGAAGGTGCTGATTTTGCTCAATTAGCCAAAGATAATT
    CAACTGATGAAAAAACAAAAGAAAATGGTGGAGAAATTACCTTTGATTCTGCTTCAACAG
    AAGTACCTGAGCAAGTCAAAAAAGCCGCTTTCGCTTTAGATGTGGATGGTGTTTCTGATG
    TGATTACAGCAACTGGCACACAAGCCTACAGTAGCCAATATTACATTGTAAAACTCACTA
    AGAAAACAGAAAAATCATCTAATATTGATGACTACAAAGAAAAATTAAAAACTGTTATCT
    TGACTCAAAAACAAAATGATTCAACATTTGTTCAAAGCATTATCGGAAAAGAATTGCAAG
    CAGCCAATATCAAGGTTAAGGACCAAGCCTTCCAAAATATCTTTACCCAATATATCGGTG
    GTGGAGATTCAAGCTCAAGCAGTAGTACATCAAACGAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    941

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPNINV200_RS04825 [old locus tag: SPNINV200_09010 ]
  • symbol: PrsA
  • description: peptidylprolyl isomerase PrsA
  • length:
  • theoretical pI:
  • theoretical MW:
  • GRAVY:

Function[edit | edit source]

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb:
  • SignalP:
  • predicted transmembrane helices (TMHMM):

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]

K Overweg, A Kerr, M Sluijter, M H Jackson, T J Mitchell, A P de Jong, R de Groot, P W Hermans
The putative proteinase maturation protein A of Streptococcus pneumoniae is a conserved surface protein with potential to elicit protective immune responses.
Infect Immun: 2000, 68(7);4180-8
[PubMed:10858235] [WorldCat.org] [DOI] (P p)
L E Cron, H J Bootsma, N Noske, P Burghout, S Hammerschmidt, P W M Hermans
Surface-associated lipoprotein PpmA of Streptococcus pneumoniae is involved in colonization in a strain-specific manner.
Microbiology (Reading): 2009, 155(Pt 7);2401-2410
[PubMed:19389773] [WorldCat.org] [DOI] (P p)