Jump to navigation
Jump to search
PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 20-DEC-2020
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae OXC141
- locus tag: SPNOXC_RS08255 [old locus tags: SPNOXC15250 SPNOXC_15250 ]
- pan locus tag?: PNEUPAN003141000
- symbol: SPNOXC_RS08255
- pan gene symbol?: phpP
- synonym:
- product: Stp1/IreP family PP2C-type Ser/Thr phosphatase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPNOXC_RS08255 [old locus tags: SPNOXC15250 SPNOXC_15250 ]
- symbol: SPNOXC_RS08255
- product: Stp1/IreP family PP2C-type Ser/Thr phosphatase
- replicon: chromosome
- strand: -
- coordinates: 1553514..1554254
- length: 741
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_017592 (1553514..1554254) NCBI
- BioCyc: SPNOXC_RS08255 BioCyc
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_1543 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601
661
721ATGGAAATTTCATTATTAACAGATGTTGGTCAGAAACGAACAAATAACCAAGACTATGTC
AACCACTATGTCAATAGAGCTGGACGTACCATGATTATTTTAGCTGATGGGATGGGAGGT
CATCGCGCAGGGAATATCGCTAGTGAAATGGCGGTGACAGACCTGGGTGTAGCTTGGGTT
GATACCCAGATCGATACAGTCAATGAAGTGCGTGAATGGTTCGCCCATTACCTAGAAATT
GAAAATCAAAAGATTCACCAGCTTGGTCAGGATGAAGCTTACAGAGGCATGGGAACTACT
TTGGAAGTCCTTGCTATTATTGATAATCAGGCTATCTATGCTCATATTGGTGATTCGCGT
ATCGGCTTGATTCGTGGAGAAGAATACCATCAGTTGACGAGCGATCATTCTTTGGTTAAT
GAATTGCTCAAGGCTGGTCAATTGACACCAGAAGAGGCAGAAGCTCATCCACAAAAAAAT
ATTATCACCCAGTCTATTGGGCAAAAAGATGAAATTCAGCCTGATTTTGGGACAGTTATC
CTTGAGTCAGGTGACTATCTCTTGCTCAATAGTGACGGCTTGACCAACATGATTTCAGGC
AGTGAGATTCGTGATATTGTAACCAGTGATATTCCTTTAGCAGATAAAACGGAGACACTT
GTTCGTTTTGCTAACAATGCAGGAGGTTTAGACAACATTACGGTTGCCCTTGTTTCTATG
AACGAGGAGGATGAAGAATGA60
120
180
240
300
360
420
480
540
600
660
720
741
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPNOXC_RS08255 [old locus tags: SPNOXC15250 SPNOXC_15250 ]
- symbol: SPNOXC_RS08255
- description: Stp1/IreP family PP2C-type Ser/Thr phosphatase
- length: 246
- theoretical pI: 4.16689
- theoretical MW: 27161
- GRAVY: -0.317886
⊟Function[edit | edit source]
- TIGRFAM: Transcription Degradation of RNA regulator of ribonuclease activity A (TIGR02998; HMM-score: 13)Regulatory functions Protein interactions regulator of ribonuclease activity A (TIGR02998; HMM-score: 13)
- TheSEED: see SPNOXC15250
- PFAM: PP2C (CL0238) PP2C_2; Protein phosphatase 2C (PF13672; HMM-score: 61.3)and 3 morePP2C; Protein phosphatase 2C (PF00481; HMM-score: 39.8)SpoIIE; Stage II sporulation protein E (SpoIIE) (PF07228; HMM-score: 18.5)no clan defined Suppressor_APC; Adenomatous polyposis coli tumour suppressor protein (PF11414; HMM-score: 14.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.007105
- TAT(Tat/SPI): 0.001069
- LIPO(Sec/SPII): 0.000464
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000406248 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAGNIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLEVLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKNIITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTETLVRFANNAGGLDNITVALVSMNEEDEE
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1543 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Linda Nováková, Lenka Sasková, Petra Pallová, Jirí Janecek, Jana Novotná, Ales Ulrych, Jose Echenique, Marie-Claude Trombe, Pavel Branny
Characterization of a eukaryotic type serine/threonine protein kinase and protein phosphatase of Streptococcus pneumoniae and identification of kinase substrates.
FEBS J: 2005, 272(5);1243-54
[PubMed:15720398] [WorldCat.org] [DOI] (P p)Makoto Osaki, Tania Arcondéguy, Amandine Bastide, Christian Touriol, Hervé Prats, Marie-Claude Trombe
The StkP/PhpP signaling couple in Streptococcus pneumoniae: cellular organization and physiological characterization.
J Bacteriol: 2009, 191(15);4943-50
[PubMed:19502404] [WorldCat.org] [DOI] (I p)