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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_0239 [new locus tag: SPT_RS01205 ]
  • pan locus tag?: PNEUPAN000918000
  • symbol: SPT_0239
  • pan gene symbol?: ypdF
  • synonym:
  • product: Xaa-Pro dipeptidase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPT_0239 [new locus tag: SPT_RS01205 ]
  • symbol: SPT_0239
  • product: Xaa-Pro dipeptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 213775..214836
  • length: 1062
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAATAAACGCGTACAAGCATTTCTAGCTAAAATGCAAGAAAAAGAACTAGATGGTATC
    ATCATCAACAATCTTAAAAACGTCTATTATTTGACTGGTTTTTGGGGCTCAAACGGAACA
    GTCTTTATCAGCCGTGACCGTCAGGTCTTAGTGACAGACTCTCGCTATATCATCGCAGCT
    AAGCAAGAAACCAGTGGTTTTGAGATTGTGGCTGATCGTGATGAATTGGCTGTCATTGCA
    GGAATTGTTAAGGACATGGGCTTGACTCGTATCGGTTTTGAAGATGAGATTTCAGTGTCT
    TATTACCACCGTATGCAGGCAGCTTTTGCAGGTTTGGACTTGCTTCCACAAACTCAGTTT
    GTGGAAGGTCTTCGTATGATTAAGGATGAGGCAGAGATTGCAGCGATTCGCAAGGCTTGT
    TCTATCTCAGACCAAGCTTTCCGCGATGCGCTTGACTTTATCAAACCAGGAAAAACTGAA
    ATTGAGATTGCCAACTTCCTTGATTTCCGCATGCGTGAGTTGGGAGCATCTGGCTTATCT
    TTTGATACGATCCTAGCTAGCGGTATCAATTCTTCTAAACCCCATGCCCATCCAATGCAC
    AAACCAGTGGAGTTGGGAGAAGCCATTACCATGGACTTCGGCTGTCTCTATGACCACTAT
    GTCAGTGATATGACCCGGACTATCTATCTAGGGCATGTTAGCGATGAGCAGGCAGAGATT
    TACAATACGGTTCTAAAAGCTAACCAAGCCTTGATTGACCAAGCTAAGGCAGGCTTAGGT
    TTCCGTGACTTTGACAAAATCCCTCGTGATATTATCATTGAGGCAGGTTATGGTGACTAC
    TTTACTCACGGCATTGGCCACGGTATTGGTCTGGATATCCATGAGGAACCCTACTTTAGC
    CAGACTTCTACAGAAACTATTAAGACAGGTATGGCCTTGACCGATGAACCAGGTATCTAT
    ATCGAAGGCAAATATGGCGTTCGTATCGAGGATGATATCCTGATTACAGAGACAGGTTGT
    GAATTATTGACCCTAGCTCCAAAAGAGTTGATAGTCATTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1062

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPT_0239 [new locus tag: SPT_RS01205 ]
  • symbol: SPT_0239
  • description: Xaa-Pro dipeptidase
  • length: 353
  • theoretical pI: 4.59783
  • theoretical MW: 39341.6
  • GRAVY: -0.0796034

Function[edit | edit source]

  • TIGRFAM:
    ectoine utilization protein EutD (TIGR02993; EC 3.-.-.-; HMM-score: 76)
    Genetic information processing Protein fate Protein modification and repair methionine aminopeptidase, type I (TIGR00500; EC 3.4.11.18; HMM-score: 72.4)
    and 1 more
    Genetic information processing Protein fate Protein modification and repair methionine aminopeptidase, type II (TIGR00501; EC 3.4.11.18; HMM-score: 34.5)
  • TheSEED  :
    • Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific)
    Protein Metabolism Protein degradation Protein degradation  Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific)
  • PFAM:
    no clan defined Peptidase_M24; Metallopeptidase family M24 (PF00557; HMM-score: 210.1)
    and 1 more
    AMP_N-like (CL0356) Creatinase_N; Creatinase/Prolidase N-terminal domain (PF01321; HMM-score: 88.6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9976
    • Cytoplasmic Membrane Score: 0.0003
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.002
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00419
    • TAT(Tat/SPI): 0.000284
    • LIPO(Sec/SPII): 0.00042
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACO24248 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFISRDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYYHRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTEIEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYDHYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAGYGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDILITETGCELLTLAPKELIVI

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator: RegR* (repression) regulon
    RegR*(TF)important in Hyaluronate utilization; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]