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serotype 4
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serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
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70585
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serotype 3
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serotype 23F
BM6001
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serotype 14
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HU-OH
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serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
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SPN034156
serotype 3
SPN034183
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SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_RS02965 [old locus tag: SPT_0595 ]
  • pan locus tag?: PNEUPAN001445000
  • symbol: SPT_RS02965
  • pan gene symbol?: —
  • synonym:
  • product: helix-hairpin-helix domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_RS02965 [old locus tag: SPT_0595 ]
  • symbol: SPT_RS02965
  • product: helix-hairpin-helix domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 553802..554197
  • length: 396
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTCAAAGAAACTCAATCGTAAAAAACAATTACGAAATGGCCTCCGTCGCGCAGGTGCC
    TTTTCAAGTACTGTGACTAAGGTTGTAGATGAGACAAAAAAAGTCGTGAAGCGTGCAGAA
    CAGTCAGCAAGCGCAGCTGGTAAGGCTGTTTCTAAAAAAGTTGAACAAGCAGTAGAAGCT
    ACCAAAGAGCAAGCTCAAAAAGTAGCTAATTCTGTAGAAGATTTTGCAGCAAATTTGGGT
    GGACTTCCACTTGATCGTGCCAAGACTTTCTATGATGAAGGAATCAAGTCTGCTTCAGAT
    TTCAAAAACTGGACTGAAAAAGAACTCCTTGCCTTGAAAGGAATCGGCCCAGCTACCATC
    AAGAAATTGAAAGAAAATGGCATCAAGTTCAAGTAA
    60
    120
    180
    240
    300
    360
    396

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_RS02965 [old locus tag: SPT_0595 ]
  • symbol: SPT_RS02965
  • description: helix-hairpin-helix domain-containing protein
  • length: 131
  • theoretical pI: 10.8401
  • theoretical MW: 14294.4
  • GRAVY: -0.643511

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage tail tape measure protein, TP901 family, core region (TIGR01760; HMM-score: 18.5)
    and 1 more
    Metabolism Transport and binding proteins Amino acids, peptides and amines mitochondrial import inner membrane, translocase subunit (TIGR00984; HMM-score: 14.6)
  • TheSEED: see SPT_0595
  • PFAM:
    HHH (CL0198) HHH_5; Helix-hairpin-helix domain (PF14520; HMM-score: 25.7)
    no clan defined ApoLp-III; Apolipophorin-III precursor (apoLp-III) (PF07464; HMM-score: 23.3)
    and 11 more
    HHH (CL0198) HHH; Helix-hairpin-helix motif (PF00633; HMM-score: 17.9)
    no clan defined DUF763; Protein of unknown function (DUF763) (PF05559; HMM-score: 16.9)
    BAF; Barrier to autointegration factor (PF02961; HMM-score: 16.7)
    Phasin; Poly(hydroxyalcanoate) granule associated protein (phasin) (PF05597; HMM-score: 16.2)
    VBS-like (CL0705) GCIP; Grap2 and cyclin-D-interacting (PF13324; HMM-score: 15.2)
    DinB (CL0310) DUF1993; Domain of unknown function (DUF1993) (PF09351; HMM-score: 14.9)
    no clan defined DUF6468; Domain of unknown function (DUF6468) (PF20072; HMM-score: 13.1)
    HHH (CL0198) DNA_pol_lambd_f; Fingers domain of DNA polymerase lambda (PF10391; HMM-score: 13)
    no clan defined Fib_alpha; Fibrinogen alpha/beta chain family (PF08702; HMM-score: 12.9)
    ATP_synthase (CL0255) ATP-synt_B; ATP synthase B/B' CF(0) (PF00430; HMM-score: 12.2)
    no clan defined YtxH; YtxH-like protein (PF12732; HMM-score: 9.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.1852
    • Cytoplasmic Membrane Score: 0.2014
    • Cell wall & surface Score: 0.1249
    • Extracellular Score: 0.4885
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.042892
    • TAT(Tat/SPI): 0.037816
    • LIPO(Sec/SPII): 0.007089
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000038619 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSASAAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFKNWTEKELLALKGIGPATIKKLKENGIKFK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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