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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_0165 [new locus tag: SP_RS00840 ]
- pan locus tag?: PNEUPAN000884000
- symbol: SP_0165
- pan gene symbol?: epiD
- synonym:
- product: flavoprotein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_0165 [new locus tag: SP_RS00840 ]
- symbol: SP_0165
- product: flavoprotein
- replicon: chromosome
- strand: +
- coordinates: 160384..160941
- length: 558
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: AE005672 (160384..160941) NCBI
- BioCyc:
- MicrobesOnline: 115706 MicrobesOnline
- PneumoBrowse for strain D39V:
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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541ATGGATAAGAAAAATTTACTTGTATTGGTTACTGGTTCGGTAGGTGCCAGTAATGTAGAT
ACATACTTATATTACATAAAAAAATTCTATAATGTTAAAGTGATACTTTCTGAAAATTCT
AAAAAATTTATAAGTAAGGAATTAATTAGTTATTTTTGTGATAAAGTTTATGATGAAATA
TTTGTTGAAGAGGTAGTTCCGCACGTTTTTCTGCCATATGAATCTGACTTACTTCTTATT
TTACCAGCTACGGCAAATGTGATTGGCAAAATTGCTAATGGTATTGCTGATGATTTAGTT
ACAGCAACTGTTTTAAACTTTAATAAAAAAATAATTTTTTGTCCCAATATGAACTCTACT
ATGTGGGACAATCACATAGTTCAAAGAAATGTATCAATTCTAAAGGAGTTGGGACATATA
TTTTTATTTGAGTCTAAAAAAACATATGAGGTAGGATTGCGTAAAGCAATAGATTCAACA
TGTTCAATGTTACAACCACAGTCGTTAGTAAAAGAACTTATCAAATTAGAAAATATTGTC
CTTGAAGAGGGACATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_0165 [new locus tag: SP_RS00840 ]
- symbol: SP_0165
- description: flavoprotein
- length: 185
- theoretical pI: 6.51353
- theoretical MW: 21038.5
- GRAVY: 0.160541
⊟Function[edit | edit source]
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase (TIGR00521; EC 4.1.1.36,6.3.2.5; HMM-score: 114.5)and 5 moreBiosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A phosphopantothenoylcysteine decarboxylase (TIGR02113; EC 4.1.1.36; HMM-score: 87.1)Unknown function General archaeoflavoprotein, MJ0208 family (TIGR02700; HMM-score: 28.7)Energy metabolism Electron transport archaeoflavoprotein AfpA (TIGR02699; HMM-score: 27)Unknown function Enzymes of unknown specificity polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases (TIGR00421; EC 4.1.1.-; HMM-score: 15.3)Cellular processes Sporulation and germination dipicolinic acid synthetase, B subunit (TIGR02852; HMM-score: 14.7)
- TheSEED :
- Phosphopantothenoylcysteine decarboxylase (EC 4.1.1.36)
- PFAM: no clan defined Flavoprotein; Flavoprotein (PF02441; HMM-score: 111.3)and 1 moreNADP_Rossmann (CL0063) Methyltransf_30; S-adenosyl-L-methionine-dependent methyltransferase (PF05430; HMM-score: 11.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.8727
- Cytoplasmic Membrane Score: 0.0139
- Cell wall & surface Score: 0
- Extracellular Score: 0.1134
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.028652
- TAT(Tat/SPI): 0.000348
- LIPO(Sec/SPII): 0.024568
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFISKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTATVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDSTCSMLQPQSLVKELIKLENIVLEEGH
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V:
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ 1.0 1.1 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
PLoS Pathog: 2018, 14(12);e1007461
[PubMed:30517198] [WorldCat.org] [DOI] (I e)