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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_1652 [new locus tag: SP_RS08155 ]
  • pan locus tag?: PNEUPAN003067000
  • symbol: SP_1652
  • pan gene symbol?: —
  • synonym:
  • product: putative membrane protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_1652 [new locus tag: SP_RS08155 ]
  • symbol: SP_1652
  • product: putative membrane protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1551105..1553879
  • length: 2775
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    ATGCCAGTGTCAAGGATGTGGTGCTCAACCAGCATCCTCAGGATATTGACAGTTTGGAGT
    ACTAGCATGATCAAGCGAAAAACTTATTGGAAGGACTTAGTTCAGTCCTTCACAGGCTCC
    AAGGGGCGTTTTTTATCCATCTTGATCCTGATGATGTTGGGATCTCTAGCCTTAGTAGGC
    CTCAAAGTAACCAGTCCCAACATGGAGGCGACAGCTAATGCTTATTTAACAACTGCTCAA
    ACCTTGGATTTGGCAGTCATGTCTAACTATGGCTTGGATCAAGCAGACCAAGAAGAACTA
    AAACAGACGGAGGGCGCAGAGGTCGAGTTTGGCTATTTGACAGATGTGACTATGGATAAT
    GGGCAGGATGCCATTCGGCTGTACTCCAAACCAGAGCGAATTTCAACCTTTCAGCTAAGA
    AAGGGACGACTTCCTCAGTCAGACAAGGAAATCGCTTTGGCCACTCATTTGCAAGGCCAA
    TACAGCGTGGGACAGGAGATTAGTTTTAAAGAAAAAGAAGAGGGTCATTCCTCTTTAAAA
    GACCATACTTATACCATTACTGGTTTTGTGGATTCGGCTGAAATCCTCTCCCAGCGAGAT
    ATGGGCTACGCAGGAAGTGGAAGTGGGACTCTGACAGCCTATGGGGTGATTTTACCTAGT
    CAATTTGATCAGAAAGTCTACAATATAGCTCGTTTGAAATATCAAGATTTAGCGGGTTTA
    AATGCCTTTTCATCAGCTTATGAAGAAAAATCCAAGCAACATCAAGAAGAGCTTGAACAA
    ATTTTATCAGATAATGGCAAGGTACGTCTGCAACTTTTGAAAAAAGAAGGACAAGAGTCT
    CTAGACAAGGGGCAAGAGACCCTTGACAAGGCTCAGACTAATTTGCAGGAAGGCAAGCGT
    CGTTTAGCAGCTGCTCAAGCTCGTATACAGGCTCAAGAAAGTCAACTAGCCTTGTTTCCT
    CAAGTTCAGAGAGAGCAGGCTAGTGCTCAACTTACCCAAGCCAAGCAGGAATTGGGCAAG
    GAAGAGGACAAACTAAAGCAAGCTGAACAAAATCTAGCCCAAGAAAAGGAAAAATTAGAA
    AAACATCAGCAAGTCTTGGATGATTTGGCGGAGCCAAGGTATCAGGTTTATAATCGTCAG
    ACCATGCCAGGTGGTCAGGGCTATCTTATGTATAGCAATGCTTCATCCAGTATTCGAGCA
    GTGGGCAATATCTTTCCTGTGGTACTTTATGCCGTAGCAGCCATGGTGACCTTTACGACC
    ATGACTCGCTTTGTAGACGAAGAGCGAACTCATGCAGGGATTTTTAAGGCCTTGGGTTAT
    CGTAGTAAGGATATTATCGCCAAGTTTCTCCTTTATGGACTAGTAGCTGGGACTGTCGGA
    ACGGCTCTAGGTAGTATACTTGGTCATTATTTGCTAGCCAGTGTAATTTCAAGTGTCATT
    ACAAAAGGCATGGTGGTGGGAGAAACTCAGATTCAGTTCTATTGGACCTATAGCTTACTA
    GCTTTTGTCTTGAGCTTGTTGGCGAGTGTGTTACCAGCCTATCTGGTGGCTTGGAGGGAA
    CTTCATGACGAAGCAGCCCAGCTTCTACTTCCTAAACCTCCTGTCAAAGGAGCTAAAATC
    TTATTGGAGCGTATCGGTTTTATCTGGCGTCGTCTCAGTTTTACTCATAAGGTAACAGCC
    CGCAACATCTTTCGTTATAAGCAGAGAATGTTGATGACAATCTTTGGTGTGGCAGGTTCT
    GTAGCTCTGCTCTTTGCAGGTTTGGGAATCCAATCTTCTGTAGCAGGAGTTCCGTCTAAA
    CAGTTTCAACAAATCCAACAGTATCAGATGCTTGTCTCTGAAAATCCTAGTGCGACCAAT
    CAGGACAAGGTAGAGCTAGCAGAAGTGTTGAAAGGGCAGGAGATACTAGCCTACCAGAAA
    ATCTATTCTAAAGCGCTATACAAGGATTTCAAAGGCAAAGCTGGTCTTCAAAACATTACT
    CTTATGATGATAGAGAAGGAAGATTTGACTCCCTTTATCCATCTTCAACATCATCAGCAG
    GAGCTGACATTAAAAGATGGCATCGTTATTACAGCTAAACTCGCCCAGCTGGCAGGTGTC
    AAGGTTGGGCAGACTTTAGAAATTGAAGGTAAGGAACTAAAGGTCGTTGCTATTACTGAG
    AACTACGTTGGTCACTTTATTTATATGAGTCAGGCTAGCTATGAGCAACTTTACGGACAG
    CTACCCCAAGCCAACACTTATCTGGTCTCATTAAGGGATACCAGTGCAACTAGTATCGAA
    AGTCAGGCGGGCTTGCTTATGAATCAATCTGCGGTGTCCAGCGTTGTCCAAAATGCTTCA
    GCCATTCGACTCTTCGACTCTATCGCTAGCTCACTCAATCAGACCATGACCATCTTGGTC
    ATCGTATCGGTTCTATTAGCTATTGTCATCCTTTACAATCTGACCAATATCAACGTAGCT
    GAGAGAATCCGTGAACTCTCCACTATCAAGGTTCTTGGTTTTCATAATAATGAAGTCACC
    CTCTACATTTACCGTGAGACGATTGTGCTGTCCCTTGTGGGAATCGTACTTGGTCTGATA
    GCTGGTTTCTATTTACACCAATTTTTGATTCAAATGATTTCGCCTGCGACTATTCTCTTT
    TATCCGCAGGTAGGCTGGGAAGTCTATGTAATCCCAGTGGCAGCAGTAAGCATCATTTTG
    ACCTTGCTTGGTTTCTTCGTCAATTATTATCTGAGAAAGGTTGATATGTTAGAAGCCCTG
    AAATCTGTAGAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2775

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_1652 [new locus tag: SP_RS08155 ]
  • symbol: SP_1652
  • description: putative membrane protein
  • length: 924
  • theoretical pI: 8.48304
  • theoretical MW: 102997
  • GRAVY: 0.0116883

⊟Function[edit | edit source]

  • TIGRFAM:
    acidobacterial duplicated orphan permease (TIGR03434; HMM-score: 41.2)
    and 7 more
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein LolE (TIGR02213; HMM-score: 23.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein, LolC/E family (TIGR02212; HMM-score: 22.8)
    SEC10/PgrA surface exclusion domain (TIGR04320; HMM-score: 16.6)
    Metabolism Transport and binding proteins Other ABC exporter transmembrane subunit, DevC protein (TIGR01185; HMM-score: 8.8)
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 7.8)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 7.8)
    mobilome CxxCx(11)CxxC protein (TIGR04402; HMM-score: 6.4)
  • TheSEED  :
    • ABC transporter permease protein
  • PFAM:
    BPD_transp_1 (CL0404) FtsX; FtsX-like permease family (PF02687; HMM-score: 103.4)
    and 7 more
    no clan defined RsgI_N; Anti-sigma factor N-terminus (PF12791; HMM-score: 16)
    Vir (CL0411) Plasmodium_Vir; Plasmodium vivax Vir protein (PF05795; HMM-score: 15.4)
    no clan defined LAT2; Linker for activation of T-cells family member 2 (PF15703; HMM-score: 13.1)
    Flagellin_C; Bacterial flagellin C-terminal helical region (PF00700; HMM-score: 11.7)
    ODV-E18; Occlusion-derived virus envelope protein ODV-E18 (PF10717; HMM-score: 10.3)
    Exonuc_VII_L; Exonuclease VII, large subunit (PF02601; HMM-score: 9)
    T3SS-Chaperone (CL0419) HrpB7; Bacterial type III secretion protein (HrpB7) (PF09486; HMM-score: 6.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9998
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0002
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.013565
    • TAT(Tat/SPI): 0.0005
    • LIPO(Sec/SPII): 0.014354
  • predicted transmembrane helices (TMHMM): 8

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MPVSRMWCSTSILRILTVWSTSMIKRKTYWKDLVQSFTGSKGRFLSILILMMLGSLALVGLKVTSPNMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDAIRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDHTYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGLNAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEGKRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEKEKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAAMVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLLASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLLPKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGLGIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKALYKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQTLEIEGKELKVVAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQAGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVAERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATILFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ 1.0 1.1 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
    The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
    PLoS Pathog: 2018, 14(12);e1007461
    [PubMed:30517198] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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