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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_2042 [new locus tag: SP_RS10325 ]
- pan locus tag?: PNEUPAN003615000
- symbol: rnpA
- pan gene symbol?: rnpA
- synonym:
- product: ribonuclease P protein component
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_2042 [new locus tag: SP_RS10325 ]
- symbol: rnpA
- product: ribonuclease P protein component
- replicon: chromosome
- strand: -
- coordinates: 1947360..1947731
- length: 372
- essential: yes [1]
⊟Accession numbers[edit | edit source]
- Location: AE005672 (1947360..1947731) NCBI
- BioCyc: see SP_RS10325
- MicrobesOnline: 117466 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1851 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361TTGAAGAAAAACTTTCGTGTAAAAAGAGAGAAAGATTTTAAGGCGATTTTCAAGGAGGGG
ACAAGTTTTGCTAATCGCAAATTTGTGGTCTACCAATTAGAAAACCAGAAAAACCGTTTT
CGAGTAGGTCTATCAGTTAGCAAAAAACTGGGGAATGCCGTCACTAGAAATCAAATTAAG
CGACGGATTCGGCATATTATCCAGAATGCAAAAGGGAGTCTGGTAGAAGATGTCGACTTT
GTTGTCATTGCTCGAAAAGGAGTCGAAACCTTGGGATACGCAGAGATGGAGAAAAATCTA
CTCCATGTATTAAAATTATCAAAGATTTACCGGGAAGGAAATGGGAGTGAAAAAGAAACT
AAAGTTGACTAG60
120
180
240
300
360
372
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_2042 [new locus tag: SP_RS10325 ]
- symbol: RnpA
- description: ribonuclease P protein component
- length: 123
- theoretical pI: 10.997
- theoretical MW: 14299.6
- GRAVY: -0.656911
⊟Function[edit | edit source]
- reaction: EC 3.1.26.5? ExPASyRibonuclease P Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
- TIGRFAM: Transcription RNA processing ribonuclease P protein component (TIGR00188; EC 3.1.26.5; HMM-score: 100.4)and 1 moreProtein fate Degradation of proteins, peptides, and glycopeptides peptidase T (TIGR01882; EC 3.4.11.-; HMM-score: 13.3)
- TheSEED :
- Ribonuclease P protein component (EC 3.1.26.5)
- PFAM: S5 (CL0329) Ribonuclease_P; Ribonuclease P (PF00825; HMM-score: 110.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.010616
- TAT(Tat/SPI): 0.002661
- LIPO(Sec/SPII): 0.00248
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNRFRVGLSVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLHVLKLSKIYREGNGSEKETKVD
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1851 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Tim van Opijnen, Andrew Camilli
A fine scale phenotype-genotype virulence map of a bacterial pathogen.
Genome Res: 2012, 22(12);2541-51
[PubMed:22826510] [WorldCat.org] [DOI] (I p)