PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 05-OCT-2017
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae MDRSPN001
- locus tag: MDRSPN_00460 [new locus tag: MDRSPN_RS02470 ]
- pan locus tag?: PNEUPAN003141000
- symbol: phpP
- pan gene symbol?: phpP
- synonym:
- product: protein phosphatase PhpP
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: MDRSPN_00460 [new locus tag: MDRSPN_RS02470 ]
- symbol: phpP
- product: protein phosphatase PhpP
- replicon: chromosome
- strand: +
- coordinates: 467709..468449
- length: 741
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: AP018391 (467709..468449) NCBI
- BioCyc:
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_1543 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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721ATGGAAATTTCATTATTAACAGATGTTGGTCAGAAACGAACAAATAACCAAGACTATGTC
AACCACTATGTCAATAGAGCTGGACGTACCATGATTATTTTAGCTGATGGGATGGGAGGT
CATCGTGCAGGGAATATCGCTAGTGAAATGGCGGTCACAGACCTGGGTGTAGCTTGGGTT
GATACCCAGATCGATACAGTCAATGAAGTGCGTGAATGGTTCGCCCATTACCTAGAAATT
GAAAATCAAAAGATTCACCAGCTTGGTCAGGATGAAGCTTACAGAGGCATGGGAACTACT
TTGGAAGTCCTTGCTATTATTGATAATCAGGCTATCTATGCTCATATTGGTGATTCGCGT
ATCGGCTTGATTCGTGGAGAAGAATACCATCAGTTGACGAGCGATCATTCCTTGGTTAAT
GAATTGCTCAAGACTGGTCAATTGACACCAGAAGAGGCAGAAGCTCATCCGCAAAAAAAT
ATTATCACCCAGTCTATTGGGCAAAAAGATGAAATTCAGCCTGATTTTGGGACAGTTATC
CTTGAGTCAGGTGACTATCTCTTGCTCAATAGTGACGGCTTGACCAACATGATTTCAGGC
AGTGAGATTCGTGATATTGTAACCAGTGATATTCCTTTAGCAGATAAAACGGAGACACTT
GTTCGTTTTGCTAACAATGCAGGAGGTTTAGACAACATTACGGTTGCCCTTGTTTCTATG
AACGAGGAGGATGCAGAATGA60
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741
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: MDRSPN_00460 [new locus tag: MDRSPN_RS02470 ]
- symbol: PhpP
- description: protein phosphatase PhpP
- length: 246
- theoretical pI: 4.19099
- theoretical MW: 27133
- GRAVY: -0.306504
⊟Function[edit | edit source]
- TIGRFAM: Transcription Degradation of RNA regulator of ribonuclease activity A (TIGR02998; HMM-score: 13)Regulatory functions Protein interactions regulator of ribonuclease activity A (TIGR02998; HMM-score: 13)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- ⊞PFAM: PP2C (CL0238) PP2C_2; Protein phosphatase 2C (PF13672; HMM-score: 63.4)and 3 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: BBA58666 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAGNIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLEVLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKTGQLTPEEAEAHPQKNIITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTETLVRFANNAGGLDNITVALVSMNEEDAE
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1543 PneumoExpress
⊞Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊞Other Information[edit | edit source]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Linda Nováková, Lenka Sasková, Petra Pallová, Jirí Janecek, Jana Novotná, Ales Ulrych, Jose Echenique, Marie-Claude Trombe, Pavel Branny
Characterization of a eukaryotic type serine/threonine protein kinase and protein phosphatase of Streptococcus pneumoniae and identification of kinase substrates.
FEBS J: 2005, 272(5);1243-54
[PubMed:15720398] [WorldCat.org] [DOI] (P p)Makoto Osaki, Tania Arcondéguy, Amandine Bastide, Christian Touriol, Hervé Prats, Marie-Claude Trombe
The StkP/PhpP signaling couple in Streptococcus pneumoniae: cellular organization and physiological characterization.
J Bacteriol: 2009, 191(15);4943-50
[PubMed:19502404] [WorldCat.org] [DOI] (I p)