From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: CXP32_07525 [new locus tag: CXP32_RS07525 ]
  • symbol: atpF
  • product: ATP synthase subunit B
  • replicon: chromosome
  • strand: -
  • coordinates: 1420920..1421414
  • length: 495
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: CP025256 (1420920..1421414) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1339 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGCACGTAACAGTAGGTGAATTAATTGGTAATTTTATTTTAATCACTGGCTCTTTTATT
    CTTTTGCTAGTCTTGATTAAAAAATTTGCATGGTCTAATATTACAGGCATTTTCGAAGAA
    AGAGCTGAAAAAATTGCTTCAGATATTGACAGAGCTGAAGAAGCCCGTCAAAAAGCAGAA
    GTATTGGCTCAAAAACGCGAAGATGAATTGGCTGGTAGCCGTAAAGAAGCTAAGACAATC
    ATTGAAAATGCAAAGGAAACAGCTGAGCAAAGTAAGGCTAATATCTTAGCAGATGCTAAA
    CTAGAAGCAGGACACTTAAAAGAAAAAGCCAATCAAGAAATTGCTCAAAATAAAGTAGAA
    GCTTTACAGAGTGTTAAGGGTGAGGTCGCAGATTTGACCATCAGCTTAGCTGGTAAAATC
    ATCTCACAAAACCTTGACAGTCATGCCCATAAAGCACTCATTGATCAGTATATCGATCAG
    CTAGGAGAAGCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    495

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: CXP32_07525 [new locus tag: CXP32_RS07525 ]
  • symbol: AtpF
  • description: ATP synthase subunit B
  • length: 164
  • theoretical pI: 5.11586
  • theoretical MW: 17986.4
  • GRAVY: -0.218902

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase F0, B subunit (TIGR01144; EC 3.6.3.14; HMM-score: 133.3)
    and 6 more
    alternate F1F0 ATPase, F0 subunit B (TIGR03321; EC 3.6.3.-; HMM-score: 57)
    Genetic information processing Transcription Degradation of RNA ribonuclease Y (TIGR03319; EC 3.1.-.-; HMM-score: 15)
    Cellular processes Cellular processes Pathogenesis protein TolA (TIGR02794; HMM-score: 10.7)
    Metabolism Transport and binding proteins Other protein TolA (TIGR02794; HMM-score: 10.7)
    flagellar assembly protein FliH (TIGR03825; HMM-score: 9.7)
    ATP synthase archaeal, H subunit (TIGR02926; EC 3.6.3.14; HMM-score: 9.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    ATP_synthase (CL0255) ATP-synt_B; ATP synthase B/B' CF(0) (PF00430; HMM-score: 94)
    and 7 more
    no clan defined RNase_Y_N; RNase Y N-terminal region (PF12072; HMM-score: 17.5)
    OmpH; Outer membrane protein (OmpH-like) (PF03938; HMM-score: 16.1)
    DUF2018; Domain of unknown function (DUF2018) (PF09442; HMM-score: 15)
    ATP_synthase (CL0255) Mt_ATP-synt_B; Mitochondrial ATP synthase B chain precursor (ATP-synt_B) (PF05405; HMM-score: 10.6)
    no clan defined MAT1; CDK-activating kinase assembly factor MAT1 (PF06391; HMM-score: 10.4)
    DUF4570; Domain of unknown function (DUF4570) (PF15134; HMM-score: 9.2)
    DivIVA; DivIVA protein (PF05103; HMM-score: 7.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helix: 1
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.067917
    • TAT(Tat/SPI): 0.001356
    • LIPO(Sec/SPII): 0.003767
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AUF85230 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEKIASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLEAGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQLGEA

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]

NCBI: 17-DEC-2017

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Xen35
  • locus tag: CXP32_07525 [new locus tag: CXP32_RS07525 ]
  • pan locus tag?: PNEUPAN002836000
  • symbol: atpF
  • pan gene symbol?: atpF
  • synonym:
  • product: ATP synthase subunit B

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: CXP32_07525 [new locus tag: CXP32_RS07525 ]
  • symbol: atpF
  • product: ATP synthase subunit B
  • replicon: chromosome
  • strand: -
  • coordinates: 1420920..1421414
  • length: 495
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: CP025256 (1420920..1421414) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1339 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGCACGTAACAGTAGGTGAATTAATTGGTAATTTTATTTTAATCACTGGCTCTTTTATT
    CTTTTGCTAGTCTTGATTAAAAAATTTGCATGGTCTAATATTACAGGCATTTTCGAAGAA
    AGAGCTGAAAAAATTGCTTCAGATATTGACAGAGCTGAAGAAGCCCGTCAAAAAGCAGAA
    GTATTGGCTCAAAAACGCGAAGATGAATTGGCTGGTAGCCGTAAAGAAGCTAAGACAATC
    ATTGAAAATGCAAAGGAAACAGCTGAGCAAAGTAAGGCTAATATCTTAGCAGATGCTAAA
    CTAGAAGCAGGACACTTAAAAGAAAAAGCCAATCAAGAAATTGCTCAAAATAAAGTAGAA
    GCTTTACAGAGTGTTAAGGGTGAGGTCGCAGATTTGACCATCAGCTTAGCTGGTAAAATC
    ATCTCACAAAACCTTGACAGTCATGCCCATAAAGCACTCATTGATCAGTATATCGATCAG
    CTAGGAGAAGCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    495

This data comes from external databases and cannot be edited.

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: CXP32_07525 [new locus tag: CXP32_RS07525 ]
  • symbol: AtpF
  • description: ATP synthase subunit B
  • length: 164
  • theoretical pI: 5.11586
  • theoretical MW: 17986.4
  • GRAVY: -0.218902

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase F0, B subunit (TIGR01144; EC 3.6.3.14; HMM-score: 133.3)
    and 6 more
    alternate F1F0 ATPase, F0 subunit B (TIGR03321; EC 3.6.3.-; HMM-score: 57)
    Genetic information processing Transcription Degradation of RNA ribonuclease Y (TIGR03319; EC 3.1.-.-; HMM-score: 15)
    Cellular processes Cellular processes Pathogenesis protein TolA (TIGR02794; HMM-score: 10.7)
    Metabolism Transport and binding proteins Other protein TolA (TIGR02794; HMM-score: 10.7)
    flagellar assembly protein FliH (TIGR03825; HMM-score: 9.7)
    ATP synthase archaeal, H subunit (TIGR02926; EC 3.6.3.14; HMM-score: 9.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    ATP_synthase (CL0255) ATP-synt_B; ATP synthase B/B' CF(0) (PF00430; HMM-score: 94)
    and 7 more
    no clan defined RNase_Y_N; RNase Y N-terminal region (PF12072; HMM-score: 17.5)
    OmpH; Outer membrane protein (OmpH-like) (PF03938; HMM-score: 16.1)
    DUF2018; Domain of unknown function (DUF2018) (PF09442; HMM-score: 15)
    ATP_synthase (CL0255) Mt_ATP-synt_B; Mitochondrial ATP synthase B chain precursor (ATP-synt_B) (PF05405; HMM-score: 10.6)
    no clan defined MAT1; CDK-activating kinase assembly factor MAT1 (PF06391; HMM-score: 10.4)
    DUF4570; Domain of unknown function (DUF4570) (PF15134; HMM-score: 9.2)
    DivIVA; DivIVA protein (PF05103; HMM-score: 7.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helix: 1
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.067917
    • TAT(Tat/SPI): 0.001356
    • LIPO(Sec/SPII): 0.003767
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AUF85230 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEKIASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLEAGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQLGEA

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

Other Information[edit | edit source]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]