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From PneumoWiki
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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae MDRSPN001
  • locus tag: MDRSPN_RS03690 [old locus tag: MDRSPN_00692 ]
  • pan locus tag?: PNEUPAN002720000
  • symbol: MDRSPN_RS03690
  • pan gene symbol?: glnH_3
  • synonym:
  • product: ABC transporter substrate-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MDRSPN_RS03690 [old locus tag: MDRSPN_00692 ]
  • symbol: MDRSPN_RS03690
  • product: ABC transporter substrate-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 699250..700065
  • length: 816
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018391 (699250..700065) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1226 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAAATCAAAAAAATGGATATTTGTTTTATGTAATTTTCTTGCAATTTTCTTCTTAGTA
    GCTTGTCAGTCAGGTTCTAATGGTTCTCAGTCTGCTGTGGATGCTATCAAACAAAAAGGG
    AAATTAGTTGTGGCAACCAGTCCTGACTATGCACCCTTTGAATTTCAATCATTGGTTGAT
    GGAAAGAACCAGGTAGTCGGTGCAGACATCGACATGGCTCAGGCTATCGCTGATGAACTT
    GGGGTTAAGTTGGAAATCTCAAGCATGAGTTTTGACAATGTTTTGACCAGTCTTCAAACT
    GGTAAGGCTGACCTAGCAGTTGCAGGAATTAGTGCTACTGACGAGAGAAAAGAAGTCTTT
    GATTTTTCAATCCCATACTATGAAAACAAGATTAGTTTCTTGGTTCGTAAGGCTGATGTG
    GAAAAATACAAGGATTTAACTAGCCTAGAAAGTGCTAATATTGCAGCCCAAAAAGGGACT
    GTTCCAGAATCAATGGTCAAGGAACAATTGCCAAAAGCTCAATTAACTTCCCTAACTAAT
    ATGGGTGAAGCAGTCAATGAATTGCAGGTTGGAAAAGTAGATGCTGTTCATATGGATGAG
    CCTGTTGCACTTAGTTATGCTGCTAAAAACGCTGGCTTAGCTGTCGCAACTGTCAGCTTG
    AAGATGAAGGACGGCGACGCCAATGCCGTTGCTCTTAGAAAAAATAGTGATGATTTGAAA
    GAAGTGGTAGACAAGGTTATCCAAAAACTTAAGGATGAAGGAACTTACCAAAGCTATCTT
    GAAAAAGCAGCAAGTCTAACTGAAGTTGAAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    816

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MDRSPN_RS03690 [old locus tag: MDRSPN_00692 ]
  • symbol: MDRSPN_RS03690
  • description: ABC transporter substrate-binding protein
  • length: 271
  • theoretical pI: 4.59788
  • theoretical MW: 29305.2
  • GRAVY: -0.102583

⊟Function[edit | edit source]

  • ⊞⊞TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines lysine-arginine-ornithine-binding periplasmic protein (TIGR01096; HMM-score: 159)
    and 4 more
    Metabolism Transport and binding proteins Amino acids, peptides and amines ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB (TIGR02995; HMM-score: 61)
    extracellular substrate-binding orphan protein, GRRM family (TIGR04262; HMM-score: 55.6)
    quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein (TIGR03871; HMM-score: 29.5)
    aromatic cluster surface protein (TIGR04313; HMM-score: 14.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • ⊞⊞PFAM:
    PBP (CL0177) SBP_bac_3; Bacterial extracellular solute-binding proteins, family 3 (PF00497; HMM-score: 191)
    and 3 more
    Lig_chan-Glu_bd; Ligated ion channel L-glutamate- and glycine-binding site (PF10613; HMM-score: 39.3)
    Cystatin (CL0121) Cystatin; Cystatin domain (PF00031; HMM-score: 15.4)
    PBP (CL0177) SBP_bac_5; Bacterial extracellular solute-binding proteins, family 5 Middle (PF00496; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞⊞PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • ⊞⊞SignalP: Signal peptide LIPO(Sec/SPII) length 21 aa
    • SP(Sec/SPI): 0.001802
    • TAT(Tat/SPI): 0.000068
    • LIPO(Sec/SPII): 0.997938
    • Cleavage Site: CS pos: 21-22. LVA-CQ. Pr: 0.9984
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000837340 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKSKKWIFVLCNFLAIFFLVACQSGSNGSQSAVDAIKQKGKLVVATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGKADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGTVPESMVKEQLPKAQLTSLTNMGEAVNELQVGKVDAVHMDEPVALSYAAKNAGLAVATVSLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=MDRSPN_RS03690&oldid=106076"
Insert paragraph

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae MDRSPN001
  • locus tag: MDRSPN_RS03690 [old locus tag: MDRSPN_00692 ]
  • pan locus tag?: PNEUPAN002720000
  • symbol: MDRSPN_RS03690
  • pan gene symbol?: glnH_3
  • synonym:
  • product: ABC transporter substrate-binding protein

Insert paragraph

⊟Genome View[edit | edit source]

Insert paragraph

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MDRSPN_RS03690 [old locus tag: MDRSPN_00692 ]
  • symbol: MDRSPN_RS03690
  • product: ABC transporter substrate-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 699250..700065
  • length: 816
  • essential: unknown

Insert paragraph

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018391 (699250..700065) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1226 PneumoBrowse

Insert paragraph

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAAATCAAAAAAATGGATATTTGTTTTATGTAATTTTCTTGCAATTTTCTTCTTAGTA
    GCTTGTCAGTCAGGTTCTAATGGTTCTCAGTCTGCTGTGGATGCTATCAAACAAAAAGGG
    AAATTAGTTGTGGCAACCAGTCCTGACTATGCACCCTTTGAATTTCAATCATTGGTTGAT
    GGAAAGAACCAGGTAGTCGGTGCAGACATCGACATGGCTCAGGCTATCGCTGATGAACTT
    GGGGTTAAGTTGGAAATCTCAAGCATGAGTTTTGACAATGTTTTGACCAGTCTTCAAACT
    GGTAAGGCTGACCTAGCAGTTGCAGGAATTAGTGCTACTGACGAGAGAAAAGAAGTCTTT
    GATTTTTCAATCCCATACTATGAAAACAAGATTAGTTTCTTGGTTCGTAAGGCTGATGTG
    GAAAAATACAAGGATTTAACTAGCCTAGAAAGTGCTAATATTGCAGCCCAAAAAGGGACT
    GTTCCAGAATCAATGGTCAAGGAACAATTGCCAAAAGCTCAATTAACTTCCCTAACTAAT
    ATGGGTGAAGCAGTCAATGAATTGCAGGTTGGAAAAGTAGATGCTGTTCATATGGATGAG
    CCTGTTGCACTTAGTTATGCTGCTAAAAACGCTGGCTTAGCTGTCGCAACTGTCAGCTTG
    AAGATGAAGGACGGCGACGCCAATGCCGTTGCTCTTAGAAAAAATAGTGATGATTTGAAA
    GAAGTGGTAGACAAGGTTATCCAAAAACTTAAGGATGAAGGAACTTACCAAAGCTATCTT
    GAAAAAGCAGCAAGTCTAACTGAAGTTGAAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    816

Insert paragraph

This data comes from external databases and cannot be edited.

Insert paragraph

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MDRSPN_RS03690 [old locus tag: MDRSPN_00692 ]
  • symbol: MDRSPN_RS03690
  • description: ABC transporter substrate-binding protein
  • length: 271
  • theoretical pI: 4.59788
  • theoretical MW: 29305.2
  • GRAVY: -0.102583

Insert paragraph

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines lysine-arginine-ornithine-binding periplasmic protein (TIGR01096; HMM-score: 159)
    and 4 more
    Metabolism Transport and binding proteins Amino acids, peptides and amines ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB (TIGR02995; HMM-score: 61)
    extracellular substrate-binding orphan protein, GRRM family (TIGR04262; HMM-score: 55.6)
    quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein (TIGR03871; HMM-score: 29.5)
    aromatic cluster surface protein (TIGR04313; HMM-score: 14.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • ⊞PFAM:
    PBP (CL0177) SBP_bac_3; Bacterial extracellular solute-binding proteins, family 3 (PF00497; HMM-score: 191)
    and 3 more
    Lig_chan-Glu_bd; Ligated ion channel L-glutamate- and glycine-binding site (PF10613; HMM-score: 39.3)
    Cystatin (CL0121) Cystatin; Cystatin domain (PF00031; HMM-score: 15.4)
    PBP (CL0177) SBP_bac_5; Bacterial extracellular solute-binding proteins, family 5 Middle (PF00496; HMM-score: 13)

Insert paragraph

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Insert paragraph

⊟Localization[edit | edit source]

  • ⊞PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • ⊞SignalP: Signal peptide LIPO(Sec/SPII) length 21 aa
    • SP(Sec/SPI): 0.001802
    • TAT(Tat/SPI): 0.000068
    • LIPO(Sec/SPII): 0.997938
    • Cleavage Site: CS pos: 21-22. LVA-CQ. Pr: 0.9984
  • predicted transmembrane helices (TMHMM): 1

Insert paragraph

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000837340 NCBI
  • UniProt:

Insert paragraph

⊟Protein sequence[edit | edit source]

  • MKSKKWIFVLCNFLAIFFLVACQSGSNGSQSAVDAIKQKGKLVVATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGKADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGTVPESMVKEQLPKAQLTSLTNMGEAVNELQVGKVDAVHMDEPVALSYAAKNAGLAVATVSLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE

Insert paragraph

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Insert paragraph

⊟Expression & Regulation[edit | edit source]

Insert paragraph

⊟Operon[edit | edit source]

Insert paragraph

⊟Regulation[edit | edit source]

Insert paragraph

⊟Expression data[edit | edit source]

Insert paragraph

⊞Biological Material[edit | edit source]

Insert paragraph

Insert paragraph

Insert paragraph

Insert paragraph

Insert paragraph

Insert paragraph

Insert paragraph

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

Insert paragraph

⊟Relevant publications[edit | edit source]

Insert paragraph