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serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: spr0571 [new locus tag: SPR_RS02895 ]
  • pan locus tag?: PNEUPAN001559000
  • symbol: spr0571
  • pan gene symbol?: ytqB
  • synonym:
  • product: Conserved hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: spr0571 [new locus tag: SPR_RS02895 ]
  • symbol: spr0571
  • product: Conserved hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 581508..582071
  • length: 564
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    TTGAAAATGAAAAGACCACTTGAGATGGCACATGATTTTTTGGCTGAGGTCGTGACAAAA
    GAGGATGTCGTAGTGGATGCGACTATGGGAAATGGTCATGACACGCTTTTTTTAGCCAAG
    CTAGCCAAGCAAGTCTATGCCTTTGATATTCAGAAGCAAGCCTTGGAAAAGACCCAAGAG
    CGTTTGCATCAGGCTGGCTTGACAAATGCCCAGTTAATCTTGCAAGGCCATGAGACACTG
    GACCAGTTTGTGACAAAAGCTAAGGCAGGGATTTTTAATTTGGGCTATTTGCCGTCAGCT
    GATAAGTCTGTCATCACCCGACCGCAGACAACGATTGAGGCATTAGAAAAGCTATGTGGC
    TTACTTGTCAAGGGTGGACGAATTGCTATTATGATTTACTATGGTCATGAAGGAGGCGAC
    CTCGAGAGAGATGCTGTCTTGGATTTTGTAATCCAGTTGAACCAACAAGAGTACACAGCT
    GCCATTTACCGAACTTTAAACCAAGTCAACAACCCGCCGTTTTTAGTGATGATTGAAAAA
    TTAGAGAGATACAGACATGGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    564

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: spr0571 [new locus tag: SPR_RS02895 ]
  • symbol: spr0571
  • description: Conserved hypothetical protein
  • length: 187
  • theoretical pI: 6.80067
  • theoretical MW: 21072.2
  • GRAVY: -0.177005

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification 23S rRNA (uracil-5-)-methyltransferase RumA (TIGR00479; EC 2.1.1.-; HMM-score: 32.5)
    and 9 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Chlorophyll and bacteriochlorphyll magnesium protoporphyrin O-methyltransferase (TIGR02021; EC 2.1.1.11; HMM-score: 18.5)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA (uracil(54)-C(5))-methyltransferase (TIGR02143; EC 2.1.1.35; HMM-score: 16.7)
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal protein L11 methyltransferase (TIGR00406; EC 2.1.1.-; HMM-score: 16.3)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit (TIGR02469; EC 2.1.1.132; HMM-score: 15.7)
    Metabolism Amino acid biosynthesis Other pyrrolysine biosynthesis protein PylD (TIGR03911; HMM-score: 14)
    Genetic information processing Protein fate Protein modification and repair protein-(glutamine-N5) methyltransferase, release factor-specific (TIGR03534; EC 2.1.1.-; HMM-score: 13.8)
    Unknown function Enzymes of unknown specificity putative methylase (TIGR00537; HMM-score: 13.5)
    Genetic information processing Protein synthesis tRNA and rRNA base modification 16S rRNA (cytosine(967)-C(5))-methyltransferase (TIGR00563; EC 2.1.1.176; HMM-score: 12.9)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone ubiquinone/menaquinone biosynthesis methyltransferase (TIGR01934; EC 2.1.1.-; HMM-score: 11.7)
  • TheSEED  :
    • Putative rRNA methylase YtqB
  • PFAM:
    NADP_Rossmann (CL0063) rRNA_methylase; Putative rRNA methylase (PF06962; HMM-score: 166.5)
    and 18 more
    Methyltransf_31; Methyltransferase domain (PF13847; HMM-score: 32.9)
    Methyltransf_25; Methyltransferase domain (PF13649; HMM-score: 31.3)
    Methyltransf_5; MraW methylase family (PF01795; HMM-score: 23.7)
    Methyltr_RsmB-F; 16S rRNA methyltransferase RsmB/F (PF01189; HMM-score: 20.7)
    Methyltransf_32; Methyltransferase domain (PF13679; HMM-score: 18.1)
    Methyltransf_11; Methyltransferase domain (PF08241; HMM-score: 17.8)
    MTS; Methyltransferase small domain (PF05175; HMM-score: 17.2)
    Methyltransf_12; Methyltransferase domain (PF08242; HMM-score: 17)
    Met_10; Met-10+ like-protein (PF02475; HMM-score: 16.4)
    tRNA_U5-meth_tr; tRNA (Uracil-5-)-methyltransferase (PF05958; HMM-score: 16.4)
    N6_N4_Mtase; DNA methylase (PF01555; HMM-score: 15.4)
    Methyltrans_SAM; S-adenosylmethionine-dependent methyltransferase (PF10672; HMM-score: 15)
    Methyltransf_18; Methyltransferase domain (PF12847; HMM-score: 14.9)
    RrnaAD; Ribosomal RNA adenine dimethylase (PF00398; HMM-score: 14.1)
    Methyltransf_33; Histidine-specific methyltransferase, SAM-dependent (PF10017; HMM-score: 13.2)
    PrmA; Ribosomal protein L11 methyltransferase (PrmA) (PF06325; HMM-score: 13)
    TehB; Tellurite resistance protein TehB (PF03848; HMM-score: 12.3)
    PDDEXK (CL0236) ERCC4; ERCC4 domain (PF02732; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9968
    • Cytoplasmic Membrane Score: 0.0011
    • Cell wall & surface Score: 0.0011
    • Extracellular Score: 0.0009
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004378
    • TAT(Tat/SPI): 0.000524
    • LIPO(Sec/SPII): 0.000482
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKMKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVYAFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSVITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAIYRTLNQVNNPPFLVMIEKLERYRHG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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