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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: spr1967 [new locus tag: SPR_RS10030 ]
  • pan locus tag?: PNEUPAN003831000
  • symbol: PTS-EII
  • pan gene symbol?: manZ_4
  • synonym:
  • product: Phosphotransferase system sugar-specific EII component

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: spr1967 [new locus tag: SPR_RS10030 ]
  • symbol: PTS-EII
  • product: Phosphotransferase system sugar-specific EII component
  • replicon: chromosome
  • strand: -
  • coordinates: 1958932..1959732
  • length: 801
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGATGAATAATAAAGTAACTAAAGTTGAACTTAAAAAAGTTTTCAAACGAAGTTTTATG
    TATGGTTCTTCATGGAACTATGAGAGAATGCAGAACCTAGGTTTTCTATATACAATTCTT
    CCAGTATTGAAAAAACTATACCCAGACAAAGATTCAGCTTCTCCTGCAATGAAACGTCAC
    CTTGAGTTTTTCAATACTCATCAAACAGCGGCACCATTTATTCTTGGAGTTACTTCCGCT
    ATGGAAGAACAAGAAGGAAATGAAGGTGCAGCTTCAATTACTGGTATTAAAGTTGGCTTG
    ATGGGGCCACTGGCTGGTCTAGGAGATAGTTTGTTCTGGCTGACACTAGTTCCTATCTGT
    TTTAGTATTGGTGCGTCTTATTCTAAAGACGGCGGTGCTTTAGGTATCTTTATCGCCTTA
    ATATTGTTTAATATTATTAATATTCCTGTTAAATATTTCGGTTTGAAATATGGGTATACT
    AAGGGTTCTAGTCTTATCCAAGAAAATAATACAAAAGGAACATTGAATCGCGTTACGAGT
    ATGGCGACAGCATTAGGGCTAGTACTAGTGGGTGGTTTGATTCCATCAATGGTTGGTATT
    AATTTTGGATTAGAATTTAAGCAGGGGGAACTTGTTATTTCTGTTCAAGAAATGATTACA
    AAATTAATTCCAGGATTTATCCCTATGGCTTTGACTTTATTAATGTGTAAATTAATTAGA
    AAAGGAAAGAATCCGGTTGTACTAATCTTTAGTGTTATGGCTATTGGAGTTATCCTAGTT
    GTTTTAGGAATTTTGAAGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    801

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: spr1967 [new locus tag: SPR_RS10030 ]
  • symbol: PTS-EII
  • description: Phosphotransferase system sugar-specific EII component
  • length: 266
  • theoretical pI: 10.1482
  • theoretical MW: 28981.5
  • GRAVY: 0.486842

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, mannose/fructose/sorbose family, IID component (TIGR00828; HMM-score: 253.7)
    Signal transduction Signal transduction PTS PTS system, mannose/fructose/sorbose family, IID component (TIGR00828; HMM-score: 253.7)
  • TheSEED  :
    • PTS system L-fucose-specific IID component
    Carbohydrates Monosaccharides Mannose Metabolism  PTS system, mannose-specific IID component
    and 1 more
    Cell Wall and Capsule Capsular and extracellular polysacchrides Sialic Acid Metabolism  PTS system, mannose-specific IID component
  • PFAM:
    no clan defined EIID-AGA; PTS system mannose/fructose/sorbose family IID component (PF03613; HMM-score: 308.8)
    and 1 more
    DUF5684; Family of unknown function (DUF5684) (PF18936; HMM-score: 9.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008827
    • TAT(Tat/SPI): 0.000698
    • LIPO(Sec/SPII): 0.001083
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLKKLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMGPLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYTKGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEMITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CcpA regulon, FucR* (repression) regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    FucR*(TF)important in Fucose utilization; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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