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serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: spr1972 [new locus tag: SPR_RS10055 ]
  • pan locus tag?: PNEUPAN003837000
  • symbol: fucA
  • pan gene symbol?: fucA
  • synonym:
  • product: L-fuculose phosphate aldolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: spr1972 [new locus tag: SPR_RS10055 ]
  • symbol: fucA
  • product: L-fuculose phosphate aldolase
  • replicon: chromosome
  • strand: -
  • coordinates: 1961864..1962517
  • length: 654
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGAGGAGGACAAGGATGTCAGATGTAAAACAAGAATTAATTAAATATGGTAAGAAGCTA
    GTAGAAACAGATTTGACGAAAGGAACAGGTGGGAATCTCAGCGTTTTCGATCGTGAAAAA
    CAATTGATGGCAATTACCCCGTCGGGTATTGATTTCTTTGAAATCAAAGAATCCGATATT
    GTAGTGATGGATATTAATGGAAATGTTGTAGAGGGAGAACGCTTGCCATCTAGCGAATGG
    TATATGCATTTGATTCAATATCAAACTCGTGATGATATCGATGCAATTATCCATGCTCAT
    ACAACTTATGCAACAGTATTAGCTTGTCTCAGAGAACCACTTCCAGCGAGTCATTATATG
    ATTGCAGTGGCAGGGAAAGATGTTCGGGTAGCTGAGTATGCAACATATGGTACGAAAGAA
    TTGGCTGTGAATGCAGCTAAAGCAATGGAAGGTCGTAGAGCAGTTTTACTAGCGAATCAT
    GGAATTTTAGCAGGTGCACAAAATTTATTGAATGCATTTAATATTGTTGAAGAAGTTGAA
    TATTGTGCAAAAATTTATTGTTTAGCTAAGAATTTTGGAGAGCCAGTAGTTCTTCCTGAT
    GAGGAGATGGAATTGATGGCAGAAAAATTTAAAACATACGGTCAGAGAAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    654

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: spr1972 [new locus tag: SPR_RS10055 ]
  • symbol: FucA
  • description: L-fuculose phosphate aldolase
  • length: 217
  • theoretical pI: 5.6927
  • theoretical MW: 24366.9
  • GRAVY: -0.186636

⊟Function[edit | edit source]

  • reaction:
    EC 4.1.2.17?  ExPASy
    L-fuculose-phosphate aldolase L-fuculose 1-phosphate = glycerone phosphate + (S)-lactaldehyde
  • TIGRFAM:
    Metabolism Energy metabolism Sugars L-fuculose phosphate aldolase (TIGR01086; EC 4.1.2.17; HMM-score: 170)
    and 4 more
    Metabolism Energy metabolism Sugars L-ribulose-5-phosphate 4-epimerase (TIGR00760; EC 5.1.3.4; HMM-score: 90.6)
    Metabolism Amino acid biosynthesis Aspartate family methylthioribulose-1-phosphate dehydratase (TIGR03328; EC 4.2.-.-; HMM-score: 77.4)
    rhamnulose-1-phosphate aldolase (TIGR02624; EC 4.1.2.19; HMM-score: 37.7)
    Cellular processes Cellular processes Biosynthesis of natural products fluorothreonine transaldolase (TIGR04506; EC 2.2.1.8; HMM-score: 20)
  • TheSEED  :
    • 5-(methylthio)ribulose-1-phosphate aldolase
    • L-fuculose phosphate aldolase (EC 4.1.2.17)
    Carbohydrates Monosaccharides L-fucose utilization  L-fuculose phosphate aldolase (EC 4.1.2.17)
  • PFAM:
    no clan defined Aldolase_II; Class II Aldolase and Adducin N-terminal domain (PF00596; HMM-score: 167)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005696
    • TAT(Tat/SPI): 0.000578
    • LIPO(Sec/SPII): 0.000622
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MRRTRMSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSGIDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVLACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAGAQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CcpA regulon, FucR* (repression) regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    FucR*(TF)important in Fucose utilization; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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