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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 16-MAY-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae EF3030
  • locus tag: EF3030_03260 [new locus tag: EF3030_RS03260 ]
  • pan locus tag?: PNEUPAN001607000
  • symbol: EF3030_03260
  • pan gene symbol?: moeB
  • synonym:
  • product: ThiF family adenylyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EF3030_03260 [new locus tag: EF3030_RS03260 ]
  • symbol: EF3030_03260
  • product: ThiF family adenylyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 624497..625645
  • length: 1149
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATTGATAGTAGATATTCTAGAACTAAAGGTTACTATTCGTTATTTTATAATGAAGAGTAT
    AATAAAATACAGAATAAAACAGTATTAGTATTAGGAGCCGGAGCCTTAGGATGTTATATA
    TCTCTAAGTCTAAGTATGTATGGAGTGAGGAAACTTATTGTCGCTGATTACGATATAATA
    GAACCATCAAATTTAAATAGGCAAATTCTTTATACAGAGTCGGATGTTGGTAAGGAGAAG
    ATTAATGTTCTTTCTCAAAAAATACACAAGTATAATTCAGATGTTCAGGTAGTACCTATT
    TCTATTAAAGTTTCTTCAGTAGAAGAATTAGAAAACATTGTTGCGGAATATGGGAGTATA
    GATTTTATCGTTAAAGCAATTGATACGCCCATTGATATTATAAAAATTGTCAATCAATTT
    GCTGTATCGCATAAGATATCCTACATATCAGGAGGGTTTAATGGATGCTATCTTATTATT
    GATAATATATATATCCCTACCATCGGTTCTTGCTTTGCTTGTCGGAATATAAACAAAGAT
    ATAAATAAGTACACTTTATCTGATAAGACAAAGTGGCCGACTACACCAGAGATGCCTGCT
    ATTTTGGGAGGGATAATGACTAATTTAATAATTAAAATATTTCTGGGATGTTATAATGAA
    ATCCTAATAGATAACGCTTACGTTTATAATATGAGAAATCATGCTCTAAGTCAAGAAAAA
    TATGTTCTGGAAAACGGAGAATGTCCAATTTGTAAAAAAAATAATAAAGTGAAAGATAAC
    AATATTAGAGCGAAAACATTTATTCGTTCAGTTTGTTTTTGCTTATTATCAGGAGGAGTA
    GCTTTTTTATCTGCTATTGGGCAGTTCACTGTTATAGAAACACAATTAATAGTATTGTTC
    TTGGGTATTATTTTTGCTATATATTATGCTTACTACAATAAAAATATTCAAACATCATTG
    GAAAATATAGTATGGCTTTTTTCATCGTTTGAGATTTTATTTTTGCTTGTTAATTTTAGA
    ACATTTATTCAGTTACCAGTGGATATTTTTATTAGTATGATAATATTTTTAATGCTGTGG
    ATATTTATTATGTTAGGTATAGTGTGTCTTAGTTATTATATAACTTTATTATTTAGCAAG
    GAGGCTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1149

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EF3030_03260 [new locus tag: EF3030_RS03260 ]
  • symbol: EF3030_03260
  • description: ThiF family adenylyltransferase
  • length: 382
  • theoretical pI: 7.84654
  • theoretical MW: 43543.8
  • GRAVY: 0.367801

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine thiazole biosynthesis adenylyltransferase ThiF (TIGR02356; EC 2.7.7.73; HMM-score: 94.2)
    and 8 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine thiamine biosynthesis protein ThiF (TIGR02354; HMM-score: 73.3)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Molybdopterin molybdopterin synthase sulfurylase MoeB (TIGR02355; HMM-score: 71.1)
    ubiquitin-activating enzyme E1 (TIGR01408; HMM-score: 55.9)
    E1-like protein-activating enzyme Gsa7p/Apg7p (TIGR01381; HMM-score: 33.3)
    PRTRC system ThiF family protein (TIGR03736; HMM-score: 17.4)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides beta-aspartyl peptidase (TIGR01975; EC 3.4.19.5; HMM-score: 14.6)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A 2-dehydropantoate 2-reductase (TIGR00745; EC 1.1.1.-; HMM-score: 13.6)
    exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (TIGR03025; HMM-score: 4.5)
  • TheSEED: data available for D39, TIGR4
  • PFAM:
    NADP_Rossmann (CL0063) ThiF; ThiF family (PF00899; HMM-score: 132.2)
    and 4 more
    Shikimate_DH; Shikimate / quinate 5-dehydrogenase (PF01488; HMM-score: 17.2)
    ApbA; Ketopantoate reductase PanE/ApbA (PF02558; HMM-score: 13)
    FAD_binding_3; FAD binding domain (PF01494; HMM-score: 12.8)
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase (PF07992; HMM-score: 11)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.33
    • Cytoplasmic Membrane Score: 9.6
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 4
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0104
    • Cytoplasmic Membrane Score: 0.832
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.1574
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.04809
    • TAT(Tat/SPI): 0.001788
    • LIPO(Sec/SPII): 0.179152
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QBF69955 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSLSMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSQKIHKYNSDVQVVPISIKVSSVEELENIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLIIDNIYIPTIGSCFACRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCYNEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLLSGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQTSLENIVWLFSSFEILFLLVNFRTFIQLPVDIFISMIIFLMLWIFIMLGIVCLSYYITLLFSKEA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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