From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 03-AUG-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ST556
  • locus tag: MYY_2109 [new locus tag: MYY_RS11115 ]
  • pan locus tag?: PNEUPAN003895000
  • symbol: MYY_2109
  • pan gene symbol?: pspC
  • synonym:
  • product: surface protein PspC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MYY_2109 [new locus tag: MYY_RS11115 ]
  • symbol: MYY_2109
  • product: surface protein PspC
  • replicon: chromosome
  • strand: -
  • coordinates: 2097138..2098874
  • length: 1737
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP003357 (2097138..2098874) NCBI
  • BioCyc: see MYY_RS11115
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    ATGCGTTATTCCATTCGTAAATTTAGTGTAGGAGTAGCTAGCGTAGCTGTTGCCAGTCTT
    TTTATGGGAAGTGTTGTACATGCGACAGAGAAAGAGGGAAGTACCCAAGCAGCCACTTCT
    TTTAATAGGGGAAATGGAAGTCAGGCAGAACAACGTGGAGAACTCGATTTAGAACGAGAT
    AAGGCAATGAAAGCGGTCAGTGAATATGTAGGAAAAATGGTGAGAGATGCCTATGTAAAA
    TCAGATAGAAAACGACATAAAAATACTGTAGCTCTAGTTAACCAGTTGGGAAACATTAAG
    AACAGGTATTTGAATGAAATAGTTCATTCAACCTCAAAAAGCCAACTACAGGAACTGATG
    ATGAAGAGTCAATCAGAAGTAGATGAAGCTGTGTCTAAATTTGAAAAGGACTCATTTTCT
    TCGTCAAGTTCAGGATCCTCCACTAAACCAGAAACTCCGCAGCCGGAAAATCCAGAGCAT
    CAAAAACCAACAACTCCAGCTCCGGATACCAAACCAAGCCCTCAACCAGAAGGCAAGAAA
    CCAAGCGTACCAGACATTAATCAGGAAAAAGAAAAAGCTAAGCTTGCTGTAGCAACCTAC
    ATGAGCAAGATTTTAGATGATATACAAAAACATCATCTGCAGAAAGAAAAACATCGTCAG
    ATTGTTGCTCTTATTAAGGAGCTTGATGAGCTTAAAAAGCAAGCTCTTTCTGAAATTGAT
    AATGTAAATACCAAAGTAGAAATTGAAAATACAGTCCACAAGATATTTGCAGACATGGAT
    GCAGTTGTGACTAAATTCAAAAAAGGCTTAACTCAGGACACACCAAAAGAACCAGGTAAC
    AAAAAACCATCTGCTCCAAAACCAGGTATGCAACCAAGTCCTCAACCAGAGGTTAAACCG
    CAGCTAGAAAAACCAAAACCAGAGGTTAAACCGCAGCTGGAAAAACCAAAACCAGAGGTT
    AAACCGCAGCTGGAAAAACCAAAACCAGAGGTTAAACCGCAGCTGGAAAAACCAAAACCA
    GAGGTTAAACCGCAGCTGGAAAAACCAAAACCAGAGGTTAAACCGCAGCTAGAAAAACCA
    AAACCAGAGGTTAAACCGCAGTTGGAAAAACCAAAACCAGAGGTTAAACCGCAGCTGGAA
    AAACCAAAACCAGAGGTTAAACCGCAGCTGGAAAAACCAAAACCAGAGGTTAAACCGCAG
    CTAGAAAAACCAAAACCAGAGGTTAAACCGCAGTTGGAAAAACCAAAACCAGAGGTTAAA
    CCGCAGCTGGAAAAACCAAAACCAGAGGTTAAACCGCAGCTGGAAAAACCAAAACCAGAG
    GTTAAACCGCAGCTGGAAAAACCAAAACCAGAGGTTAAACCGCAGCTGGAAAAACCAAAA
    CCAGAGGTTAAACCGCAGCTAGAAAAACCAAAACCAGAGGTTAAACCGCAGCTAGAAAAA
    CCAAAACCAGAGGTTAAACCGCAGCTGGAAAAACCAAAACCAGAGGTTAAACCGCAGCCG
    GAAAAACCAAAACCAGATAATAGCAAGCCACAAGCAGATGATAAGAAGCCATCAACTACA
    AATAATTTAAGCAAGGACAAGCAACCTTCTAACCAAGCTTCAACAAACGAAAAAGCAACA
    AATAAACCGAAGAAGTCATTGCCATCAACTGGATCTATTTCAAATCTAGCACTTGAAATT
    GCAGGTCTTCTTACCTTGGCGGGGGCAACCATTCTTGCTAAGAAAAGAATGAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1737

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MYY_2109 [new locus tag: MYY_RS11115 ]
  • symbol: MYY_2109
  • description: surface protein PspC
  • length: 578
  • theoretical pI: 10.3888
  • theoretical MW: 64691.4
  • GRAVY: -1.19758

⊟Function[edit | edit source]

  • TIGRFAM:
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 49.7)
    and 2 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 22.3)
    GeoRSP system SPASM domain protein (TIGR04304; HMM-score: 12)
  • TheSEED  :
    • Choline binding protein A
    Stress Response Osmotic stress Choline and Betaine Uptake and Betaine Biosynthesis  Choline binding protein A
  • PFAM:
    no clan defined RICH; RICH domain (PF05062; HMM-score: 164.7)
    and 6 more
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 41.1)
    Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 34.9)
    EDD (CL0245) Dak1; Dak1 domain (PF02733; HMM-score: 15.7)
    B_GA (CL0598) DUF1542; Domain of Unknown Function (DUF1542) (PF07564; HMM-score: 14.9)
    EFTPs (CL0575) Ribosomal_L35Ae; Ribosomal protein L35Ae (PF01247; HMM-score: 14)
    Phospoesterase (CL0171) FBPase_glpX; Bacterial fructose-1,6-bisphosphatase, glpX-encoded (PF03320; HMM-score: 10.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0036
    • Cytoplasmic Membrane Score: 0.0002
    • Cell wall & surface Score: 0.919
    • Extracellular Score: 0.0772
  • SignalP: Signal peptide SP(Sec/SPI) length 28 aa
    • SP(Sec/SPI): 0.989718
    • TAT(Tat/SPI): 0.00452
    • LIPO(Sec/SPII): 0.003607
    • Cleavage Site: CS pos: 28-29. VHA-TE. Pr: 0.9201
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AFC95759 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRYSIRKFSVGVASVAVASLFMGSVVHATEKEGSTQAATSFNRGNGSQAEQRGELDLERDKAMKAVSEYVGKMVRDAYVKSDRKRHKNTVALVNQLGNIKNRYLNEIVHSTSKSQLQELMMKSQSEVDEAVSKFEKDSFSSSSSGSSTKPETPQPENPEHQKPTTPAPDTKPSPQPEGKKPSVPDINQEKEKAKLAVATYMSKILDDIQKHHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQDTPKEPGNKKPSAPKPGMQPSPQPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQLEKPKPEVKPQPEKPKPDNSKPQADDKKPSTTNNLSKDKQPSNQASTNEKATNKPKKSLPSTGSISNLALEIAGLLTLAGATILAKKRMK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=MYY_2109&oldid=162633"