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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 17-JUN-2018
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae NCTC7466
 - locus tag: NCTC7466_00133 [new locus tag: DQM66_RS00735 ]
 - pan locus tag?: PNEUPAN000801000
 - symbol: NCTC7466_00133
 - pan gene symbol?: cibB
 - synonym:
 - product: bacteriocin-type signal sequence domain-containing protein
 
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
 - locus tag: NCTC7466_00133 [new locus tag: DQM66_RS00735 ]
 - symbol: NCTC7466_00133
 - product: bacteriocin-type signal sequence domain-containing protein
 - replicon: chromosome
 - strand: -
 - coordinates: 137824..137976
 - length: 153
 - essential: unknown
 
⊟Accession numbers[edit | edit source]
- Location: LS483374 (137824..137976) NCBI
 - BioCyc:
 - MicrobesOnline:
 - PneumoBrowse for strain D39V: SPV_0132 PneumoBrowse
 
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121ATGATGAAAAATTTGAACAACTATCGTGAAATTTCTAATAAGGAATTGCAAGAAATCAAG
GGTGGCTTTGGTGTAGGTGTTGGTATCGCTTTATTTATGGCAGGTTATACCATTGGAAAA
GACCTTCGTAAAAAGTTTGGTAAGTCATGCTAG60
120
153 
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: NCTC7466_00133 [new locus tag: DQM66_RS00735 ]
 - symbol: NCTC7466_00133
 - description: bacteriocin-type signal sequence domain-containing protein
 - length: 50
 - theoretical pI: 10.3274
 - theoretical MW: 5556.54
 - GRAVY: -0.282
 
⊟Function[edit | edit source]
- TIGRFAM: class IIb bacteriocin, lactobin A/cerein 7B family (TIGR03949; HMM-score: 19.1)bacteriocin-type signal sequence (TIGR01847; HMM-score: 18.4)and 1 moreCellular processes Biosynthesis of natural products natural product precursor, GG-Bacteroidales family (TIGR04149; HMM-score: 13.4)
 - TheSEED: data available for D39, Hungary19A-6, TIGR4
 - PFAM: GG-leader (CL0400) ComC; COMC family (PF03047; HMM-score: 24.1)Bacteriocin_IIc; Bacteriocin class II with double-glycine leader peptide (PF10439; HMM-score: 20.9)and 3 moreLactococcin; Lactococcin-like family (PF04369; HMM-score: 15.3)no clan defined DUF5841; Family of unknown function (DUF5841) (PF19159; HMM-score: 14.1)GG-leader (CL0400) L_biotic_typeA; Type-A lantibiotic (PF04604; HMM-score: 12.9)
 
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
 - modifications:
 - cofactors:
 - effectors:
 
⊟Localization[edit | edit source]
- PSORTb: Extracellular
- Cytoplasmic Score: 0.24
 - Cytoplasmic Membrane Score: 0.05
 - Cellwall Score: 0.8
 - Extracellular Score: 8.91
 - Internal Helix: 1
 
 - DeepLocPro: Extracellular
- Cytoplasmic Score: 0
 - Cytoplasmic Membrane Score: 0
 - Cell wall & surface Score: 0
 - Extracellular Score: 1
 
 - SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.161508
 - TAT(Tat/SPI): 0.009079
 - LIPO(Sec/SPII): 0.074357
 
 - predicted transmembrane helices (TMHMM): 1
 
⊟Accession numbers[edit | edit source]
- GI:
 - RefSeq: SQG01194 NCBI
 - UniProt:
 
⊟Protein sequence[edit | edit source]
- MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRKKFGKSC
 
⊟Experimental data[edit | edit source]
- protein localization:
 - interaction partners:
 
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0132 PneumoExpress
 
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]