From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_2240 [new locus tag: SP70585_RS11130 ]
  • pan locus tag?: PNEUPAN003691000
  • symbol: SP70585_2240
  • pan gene symbol?: —
  • synonym:
  • product: transcriptional regulator, GntR family

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_2240 [new locus tag: SP70585_RS11130 ]
  • symbol: SP70585_2240
  • product: transcriptional regulator, GntR family
  • replicon: chromosome
  • strand: -
  • coordinates: 2049800..2050516
  • length: 717
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGGCGAAACCCTTGGTAGAAAAAGCATCAGAACGCTTATTGGAATTGATTTTGGAAAGA
    GGATATGAGGTTGGAGACAAGCTTCCAAATGAGTATGAATTAGCCCAAGATTTAGAAGTT
    GGACGTTCGACTGTTCGTGAAGCTGTTCGGAGTTTGGCTACTCGCAATATTCTGGAGGTG
    CGCCAAGGGTCAGGGACATACATCAGCTCTAAAAAAGGAGTATCGGAAGACCCTCTAGGT
    TTTTCTTTGGTAAGAGACCGTGTGAAGTTGACAACGGATTTGTTTGAAGTGCGGTACTTA
    CTTGAACCGAGAATTGCGGAGCGTGTAGCTCAATTTGCTTCGGATGAAGATGTTGCTAAA
    TTAGAGGAAATTGTCCTTGCAATTGAAGAGGCTGTAGCTGCTGGAGACACGAAGCATTTG
    GAGTTGGATGTGAAATTTCATTGTATGCTGGCTGAGATGAGTGGGAATCTGGCAATGACT
    AGCCTGATGCCTGTCATTAATCAGTCCATTCATCTGATCAATGAAAATTACTCAAATCGT
    CAGATGAAATCAAATAGTTTACAGGCGCACAGAAATATCTTAATGGCAATCAAACAACGC
    CACCCTGTTGCAGCTTATGATAGTATGTTAGCGCATATTATATCGGTAAGACAGGTTGTT
    TTAAGCGAATGGTTCGATAAAGACATGACCTTGCATGGTCTAAATGATCATAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    717

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_2240 [new locus tag: SP70585_RS11130 ]
  • symbol: SP70585_2240
  • description: transcriptional regulator, GntR family
  • length: 238
  • theoretical pI: 5.87078
  • theoretical MW: 26896.7
  • GRAVY: -0.22479

⊟Function[edit | edit source]

  • TIGRFAM:
    phosphonate utilization associated transcriptional regulator (TIGR03338; HMM-score: 67.3)
    and 9 more
    Metabolism Transport and binding proteins Anions phosphonate metabolism transcriptional regulator PhnF (TIGR02325; HMM-score: 48.9)
    Signal transduction Regulatory functions DNA interactions phosphonate metabolism transcriptional regulator PhnF (TIGR02325; HMM-score: 48.9)
    Signal transduction Regulatory functions DNA interactions trehalose operon repressor (TIGR02404; HMM-score: 40.8)
    Metabolism Energy metabolism Amino acids and amines histidine utilization repressor (TIGR02018; HMM-score: 40.4)
    Signal transduction Regulatory functions DNA interactions histidine utilization repressor (TIGR02018; HMM-score: 40.4)
    Metabolism Fatty acid and phospholipid metabolism Biosynthesis fatty acid metabolism transcriptional regulator FadR (TIGR02812; HMM-score: 24.4)
    Metabolism Fatty acid and phospholipid metabolism Degradation fatty acid metabolism transcriptional regulator FadR (TIGR02812; HMM-score: 24.4)
    Signal transduction Regulatory functions DNA interactions fatty acid metabolism transcriptional regulator FadR (TIGR02812; HMM-score: 24.4)
    Signal transduction Regulatory functions DNA interactions phosphonate utilization transcriptional regulator PhnR (TIGR03337; HMM-score: 19.4)
  • TheSEED  :
    • Transcriptional regulator, GntR family
  • PFAM:
    FadR-C (CL0388) FCD; FCD domain (PF07729; HMM-score: 82.9)
    HTH (CL0123) GntR; Bacterial regulatory proteins, gntR family (PF00392; HMM-score: 67.1)
    and 4 more
    TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 17.4)
    HTH_41; Helix-turn-helix domain (PF14502; HMM-score: 15.4)
    Fe_dep_repress; Iron dependent repressor, N-terminal DNA binding domain (PF01325; HMM-score: 12.5)
    HTH_11; HTH domain (PF08279; HMM-score: 12.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002779
    • TAT(Tat/SPI): 0.000637
    • LIPO(Sec/SPII): 0.000343
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MAKPLVEKASERLLELILERGYEVGDKLPNEYELAQDLEVGRSTVREAVRSLATRNILEVRQGSGTYISSKKGVSEDPLGFSLVRDRVKLTTDLFEVRYLLEPRIAERVAQFASDEDVAKLEEIVLAIEEAVAAGDTKHLELDVKFHCMLAEMSGNLAMTSLMPVINQSIHLINENYSNRQMKSNSLQAHRNILMAIKQRHPVAAYDSMLAHIISVRQVVLSEWFDKDMTLHGLNDHK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SP70585_2240&oldid=31442"