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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_2234 [new locus tag: SP70585_RS11100 ]
  • pan locus tag?: PNEUPAN003697000
  • symbol: SP70585_2234
  • pan gene symbol?: —
  • synonym:
  • product: beta-N-acetylglucosaminidase/beta-glucosidase (3-beta-N-acetyl-D-glucosaminidase/beta-D- glucosidase)(Nag3)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_2234 [new locus tag: SP70585_RS11100 ]
  • symbol: SP70585_2234
  • product: beta-N-acetylglucosaminidase/beta-glucosidase (3-beta-N-acetyl-D-glucosaminidase/beta-D- glucosidase)(Nag3)
  • replicon: chromosome
  • strand: -
  • coordinates: 2043062..2044852
  • length: 1791
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    ATGACACATTTGGTAGACTTACGGAAGAAACCTTATAACCTTGATGAAGAAGCTATTTCA
    TGGGTTGAAAATACGATTGCTCAGATGACATTGGATGAAAAAATAGGACATCTCTTTGTC
    AACATGGGTATCCAGCGGACGGAGAAATATCTGACAGGAGTATTGGAAGATTACAAGATT
    GCTGCTGTTCGGTATAATCCAGGGCCAGCGGCAGATATTTGGGAACAAAACTATATTTTG
    CAAACTAAGTCCAAAATTCCTCTCTTAATAGCAGCAAACACAGAATCTGGTGGAAATGGT
    GCTGTTACAGATGGAACAAAAATTGGCGATGAAATCAAAATTGCAGCAACAGCTGATTCT
    CGCCATGCTTATGAGATGGGGAAAGTTGCAGGGATTGAAGCAGCAGCAGTAGGCTGTAAC
    GCTTCCTTTGCACCGATTATGGATCTTAGCCGCAACTGGCGAAATCCAATTATCGCCAAT
    CGTACTTGGGGAGCAGATGTTGACCAAGTGATTGAACTGTCTAAAGAATACATGCGTGGG
    ATTATGGAACATGGCATTGTGCCTTTTGCGAAGCATTTTCCTGGCGATGGTATTGATGAA
    CGCGATCACCACCTCTCTTTTGCTTCTAATCCAATGACAAAATCTGAATGGATGGAAACC
    TTTGGACGGATTTACGGTGAAATGGCTGATGCAGGTCTTCCAGGTATCATGGCGGGGCAC
    ATTCATTTGCCAAATGTTGAGAAAGAAATGCATCCAGAACGTGAATTGGATGATATGTTG
    CCAGCTTCGTTGAATAAAACCCTCTTGGATGAATTGTTGCGTGGGGAGTTAGGCTACAAC
    GGCGCAATTGTGACGGATGCTAGTCACATGATTGGTATGACAGCATCTATGCCACGTCGT
    GAGCTCTTACCGACAGCTATTGAAGCGGGCTGCGATCTCTTCCTCTTTTTCAATGATCCT
    GAAGAAGATTTGCAATGGATGAAAGAGGGGTTGAAAAATGGACTTCTCACTGAGGAGCGG
    CTCCATGATGCTCTTCGTCGGACCTTGGGCTTGAAAGCTAAACTCGGCCTCCACCTTTTT
    GAAGGTCGTCGTCAGGAAATTATGTTGCCAAAAGAAGAAGCGCTGGCTTTAATTGGAAAA
    GATGAGGCTAAAAATCTTGCAAAAGAAGTAGCTGACAAGGCTATTACCTTGGTAAAATCC
    AAGCAAGAAGGCATTTTCCCAGTCAATCCAGATCGCTATAAACGGATTTTATTGGTTGAA
    GTCGACGGCTACAAAGGTGGCTTTGGTGCCATGATTAATGCAGGAAAGAAGAGGGCGGCT
    GATACGCTAAAAGAATTGTTAGAAGCACGAGGTCACGAAGTGTCTATCTGGGAAAATACA
    GAAGCAAGGATTGCCAAATTACCAGAAGAAGAAAGACCAGCTGCGATTGCTAATGTCTAT
    GCATCTAAGCGTCCTATTGCAGAAATCACAGATAACTATGATTTGATTATCAATTTGGTT
    GATGTCAATTCAGGTGGAACAACTCAACGAATTATTTGGCCTGCTGCCAAGGGAACACCA
    GATCAGCCGTTCTATGTTCATGAAATACCAACCATCGTTGTTTCTGTTCAGCATCCCTTT
    GCTCTGGCAGATATGCCACAAGTAGCAACCTATATCAATGCCTATGATGGTTTACCAGTA
    ACTTTGGAAACCTTAGTTACCAAACTAGCAGGAGAATCATCGTTTACAGGAGTGTCCCCT
    GTTGATGCTTACTGTGGCTTGGTAGATACACATATTTGGCGTGGGAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1791

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_2234 [new locus tag: SP70585_RS11100 ]
  • symbol: SP70585_2234
  • description: beta-N-acetylglucosaminidase/beta-glucosidase (3-beta-N-acetyl-D-glucosaminidase/beta-D- glucosidase)(Nag3)
  • length: 596
  • theoretical pI: 5.04852
  • theoretical MW: 65941.9
  • GRAVY: -0.245302

⊟Function[edit | edit source]

  • reaction:
    EC 3.2.1.21?  ExPASy
    Beta-glucosidase Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose
    EC 3.2.1.52?  ExPASy
    Beta-N-acetylhexosaminidase Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
  • TIGRFAM:
  • TheSEED  :
    • Beta-hexosaminidase (EC 3.2.1.52), GH3 family
    Carbohydrates Aminosugars N-Acetyl-Galactosamine and Galactosamine Utilization  Beta-hexosaminidase (EC 3.2.1.52)
    and 1 more
    Nucleosides and Nucleotides Purines Purine Utilization  Beta-hexosaminidase (EC 3.2.1.52)
  • PFAM:
    Glyco_hydro_tim (CL0058) Glyco_hydro_3; Glycosyl hydrolase family 3 N terminal domain (PF00933; HMM-score: 196.4)
    and 1 more
    PDDEXK (CL0236) DUF1887; Domain of unknown function (DUF1887) (PF09002; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001682
    • TAT(Tat/SPI): 0.00018
    • LIPO(Sec/SPII): 0.000225
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTHLVDLRKKPYNLDEEAISWVENTIAQMTLDEKIGHLFVNMGIQRTEKYLTGVLEDYKIAAVRYNPGPAADIWEQNYILQTKSKIPLLIAANTESGGNGAVTDGTKIGDEIKIAATADSRHAYEMGKVAGIEAAAVGCNASFAPIMDLSRNWRNPIIANRTWGADVDQVIELSKEYMRGIMEHGIVPFAKHFPGDGIDERDHHLSFASNPMTKSEWMETFGRIYGEMADAGLPGIMAGHIHLPNVEKEMHPERELDDMLPASLNKTLLDELLRGELGYNGAIVTDASHMIGMTASMPRRELLPTAIEAGCDLFLFFNDPEEDLQWMKEGLKNGLLTEERLHDALRRTLGLKAKLGLHLFEGRRQEIMLPKEEALALIGKDEAKNLAKEVADKAITLVKSKQEGIFPVNPDRYKRILLVEVDGYKGGFGAMINAGKKRAADTLKELLEARGHEVSIWENTEARIAKLPEEERPAAIANVYASKRPIAEITDNYDLIINLVDVNSGGTTQRIIWPAAKGTPDQPFYVHEIPTIVVSVQHPFALADMPQVATYINAYDGLPVTLETLVTKLAGESSFTGVSPVDAYCGLVDTHIWRGN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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