PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 15-OCT-2021

⊟Summary

• organism: Streptococcus pneumoniae 70585
• locus tag: SP70585_RS10030 [old locus tag: SP70585_2019 ]
• pan locus tag^?: PNEUPAN003521000
• symbol: recA
• pan gene symbol^?: recA
• synonym:
• product: recombinase RecA

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SP70585_RS10030 [old locus tag: SP70585_2019 ]
• symbol: recA
• product: recombinase RecA
• replicon: chromosome
• strand: -
• coordinates: 1856302..1857468
• length: 1167
• essential: unknown other strains

⊟Accession numbers

• Location: NC_012468 (1856302..1857468) NCBI
• BioCyc: SP70585_RS10030 BioCyc
• MicrobesOnline: see SP70585_2019
• PneumoBrowse for strain D39V: SPV_1739 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  
  ATGGCGAAAAAACCAAAAAAATTAGAAGAAATTTCAAAAAAATTTGGGGCAGAACGTGAA
  AAGGCCTTGAATGACGCTCTTAAATTGATTGAGAAAGACTTTGGTAAAGGATCAATCATG
  CGTTTGGGTGAACGTGCGGAGCAAAAGGTGCAAGTGATGAGCTCAGGTTCTTTAGCTCTT
  GACATTGCCCTTGGCTCAGGTGGTTATCCTAAGGGACGTATCATCGAAATCTATGGCCCA
  GAGTCATCTGGTAAGACAACGGTTGCCCTTCATGCAGTTGCACAAGCGCAAAAAGAAGGT
  GGGATTGCTGCCTTTATCGATGCGGAACATGCCCTTGATCCAGCTTATGCTGCGGCCCTT
  GGTGTCAATATTGACGAATTGCTCTTGTCTCAACCAGACTCAGGAGAGCAAGGTCTTGAG
  ATTGCGGGAAAATTGATTGACTCAGGTGCAGTTGATCTTGTCGTAGTCGACTCAGTTGCT
  GCCCTTGTTCCTCGTGCGGAAATTGATGGAGATATCGGAGATAGCCATGTTGGTTTGCAG
  GCTCGTATGATGAGCCAGGCCATGCGTAAACTTGGCGCCTCTATCAATAAAACCAAAACA
  ATTGCCATTTTTATCAACCAATTGCGTGAAAAAGTTGGAGTGATGTTTGGAAATCCAGAA
  ACAACACCGGGCGGACGTGCTTTGAAATTCTATGCTTCAGTCCGCTTGGATGTTCGTGGT
  AATACACAAATTAAGGGAACTGGTGACCAAAAAGAAACCAATGTCGGTAAAGAAACTAAG
  ATTAAGGTTGTAAAAAATAAGGTAGCTCCACCGTTTAAGGAAGCCGTAGTTGAAATTATG
  TACGGAGAAGGAATTTCTAAGACTGGTGAGCTTTTGAAGATTGCAAGCGATTTGGATATT
  ATCAAAAAAGCAGGGGCTTGGTATTCTTACAAAGATGAAAAAATTGGGCAAGGTTCTGAA
  AATGCTAAGAAATACTTGGCAGAGCACCCAGAAATCTTTGATGAAATTGATAAGCAAGTC
  CGTTCTAAATTTGGCTTGATTGATGGAGAAGAAGTTTCAGAACAAGATACTGAAAACAAA
  AAAGATGAGCCAAAGAAAGAAGAAGCAGTGAATGAAGAAGTTACGCTTGACTTAGGCGAT
  GAACTTGAAATCGAAATTGAAGAATAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
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  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1167
  

⊟Protein

⊟General

• locus tag: SP70585_RS10030 [old locus tag: SP70585_2019 ]
• symbol: RecA
• description: recombinase RecA
• length: 388
• theoretical pI: 4.84048
• theoretical MW: 41953.5
• GRAVY: -0.386856

⊟Function

• TIGRFAM:
  Genetic information processing DNA metabolism DNA replication, recombination, and repair protein RecA (TIGR02012; HMM-score: 534.8)
  and 7 more
  DNA repair and recombination protein RadB (TIGR02237; HMM-score: 54.4)
  Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA repair and recombination protein RadA (TIGR02236; HMM-score: 37.6)
  DNA repair protein RAD51 (TIGR02239; HMM-score: 34.8)
  meiotic recombinase Dmc1 (TIGR02238; HMM-score: 34.2)
  Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA repair protein RadA (TIGR00416; HMM-score: 23.8)
  KaiC domain protein, PAE1156 family (TIGR03881; HMM-score: 18.2)
  KaiC domain protein, AF_0351 family (TIGR03880; HMM-score: 15.2)
• TheSEED: see SP70585_2019
• PFAM:
  P-loop_NTPase (CL0023) RecA; recA bacterial DNA recombination protein (PF00154; HMM-score: 465.3)
  and 7 more
  Rad51; Rad51 (PF08423; HMM-score: 39.7)
  ATPase; KaiC (PF06745; HMM-score: 28.3)
  ATPase_2; ATPase domain predominantly from Archaea (PF01637; HMM-score: 20.6)
  AAA_24; AAA domain (PF13479; HMM-score: 18.7)
  AAA_16; AAA ATPase domain (PF13191; HMM-score: 17.4)
  AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 15)
  AAA_25; AAA domain (PF13481; HMM-score: 14.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 9.97
  • Cytoplasmic Membrane Score: 0
  • Cellwall Score: 0.01
  • Extracellular Score: 0.02
  • Internal Helices: 0
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.023194
  • TAT(Tat/SPI): 0.006544
  • LIPO(Sec/SPII): 0.00085
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_001085463 NCBI
• UniProt: see SP70585_2019

⊟Protein sequence

• MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGERAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAVVEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFDEIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: recA < SP70585_RS10035

⊟Regulation

• data available for D39, TIGR4

⊟Expression data

• PneumoExpress for strain D39V: SPV_1739 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications