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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JAN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_0566 [new locus tag: SPAP_RS11410 ]
  • pan locus tag?: PNEUPAN000276000
  • symbol: SPAP_0566
  • pan gene symbol?: uvrB_1
  • synonym:
  • product: DNA or RNA helicases of superfamily II

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_0566 [new locus tag: SPAP_RS11410 ]
  • symbol: SPAP_0566
  • product: DNA or RNA helicases of superfamily II
  • replicon: chromosome
  • strand: +
  • coordinates: 529040..530356
  • length: 1317
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP002121 (529040..530356) NCBI
  • BioCyc: see SPAP_RS11410
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    TTGACTTTCGAAGAGGAGGAGGCTATCCGTTATACGGCATCAGGTCGTGAAAAGGTAATC
    GGCTATGTTGGACAGTACGGTGGGACTAAGAAATGGCTGAGTAAACTGGTTGATGTCGTT
    ATGATTCAATCTCTATTTAAGTTGGAAAATAGTCAAAGTCTTTTGGATGAGTATGAGATG
    ATGATTGTGGATGAGTGTCATCATGTCTCTGCCTTGATGTTTGAAAAAGTTGTTGCTCAG
    TTTAGAGGGAAGTATCTTTACGGTTTGACGGCTACGCCTGAGCGTAAGAATGGTCATGAG
    CCTATTGTTTTTCAGAGAATTGGTGAGATACTCCATACTGCTGATAAGAGGGAAACGGAT
    TTTAAACGGCAATTGCAATTAAGATCCACTTCTTTTGGTCATTTGGAGATTGAAAAGACC
    AAAGCAAGTAATTTTATACAGCTTAGTAATTGGATTGCTACTGACTCAGCGAGGAATCAG
    TTGATTCTCAAGGATATTCTAGCCCAAGTGGCAGAAGGACGGAATATCTTGGTTTTAGTT
    AATCGAATTCAACAGATAGATGTCTTTGAAAAATTATTGAAAGAGAAAGAGGTTGATGAC
    TGTTACATTATTAGCGGAAAAACCAAAGTCCGAGAGAGAACGAGTTTACTGGAGACGTTA
    GAACAGTTAGATAAAGGGTTTGTTTTGTTGTCTACTGGAAAATACATTGGCGAAGGTTTT
    GACTTACCTCAGTTGGACACGCTTATCTTGGCAGCACCCTTTTCTTGGAAAAATAATTTG
    ATTCAGTATGCAGGTCGGATTCATAGAAACTACAAGGATAAGTCTTTGGTGCGGATTTTC
    GATTATGTGGATATTCATGTTCCTTATTTAGAAAAGATGTTTCAGAAACGACAAGTAGCT
    TATCGAAAGATGGATTATCGTGCCATTGAGGGTGAGGAGAAACAATTCGTTTATGTTGAT
    AGTAGATATGAGAAGGTGTTGAGAGAGGACTTAGCAGGGGAAAGACAGGAATGTATGCTT
    ATTTTACCTTATGTGCACCAGACAAAACTGATGAATTTTCTAAAAGAATTTAGGATTAGT
    CAAATTGAGATATGTATACCAGAGACGGTTGTAAATAAAGCATTGCTAGATCAGTTGAAG
    AGCCAGAAAATTAAAGTGTCTTTTACTCAATCAAAAATAGTAACGCCTATTCTTTTGGTG
    AATAAGACTATTGTTTGGTATGGTGCAATGCCATTATTAGGGAAGGTAGATGAGATGACC
    ATATTACGTTTGGAATTAGCTAGTATAGTTTCTGAACTAGTGGCAGGTTTACGATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1317

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_0566 [new locus tag: SPAP_RS11410 ]
  • symbol: SPAP_0566
  • description: DNA or RNA helicases of superfamily II
  • length: 438
  • theoretical pI: 8.50233
  • theoretical MW: 50793.8
  • GRAVY: -0.193379

⊟Function[edit | edit source]

  • TIGRFAM:
    DNA phosphorothioation system restriction enzyme (TIGR04095; HMM-score: 41.5)
    and 2 more
    CRISPR-associated helicase Cas3 (TIGR01587; HMM-score: 24.4)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA repair helicase rad25 (TIGR00603; EC 3.6.4.12; HMM-score: 20.7)
  • TheSEED  :
    • DNA/RNA HELICASE (DEAD/DEAH BOX FAMILY)
  • PFAM:
    P-loop_NTPase (CL0023) Helicase_C; Helicase conserved C-terminal domain (PF00271; HMM-score: 43.1)
    ResIII; Type III restriction enzyme, res subunit (PF04851; HMM-score: 38)
    and 3 more
    iSTAND; inactive STAND (PF19995; HMM-score: 17.6)
    Helicase_C_2; Helicase C-terminal domain (PF13307; HMM-score: 15.9)
    Ferritin (CL0044) AurF; P-aminobenzoate N-oxygenase AurF (PF11583; HMM-score: 12.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8438
    • Cytoplasmic Membrane Score: 0.1451
    • Cell wall & surface Score: 0.0069
    • Extracellular Score: 0.0042
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003519
    • TAT(Tat/SPI): 0.000287
    • LIPO(Sec/SPII): 0.001388
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM84159 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRSTSFGHLEIEKTKASNFIQLSNWIATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFVLLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDYRAIEGEEKQFVYVDSRYEKVLREDLAGERQECMLILPYVHQTKLMNFLKEFRISQIEICIPETVVNKALLDQLKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTILRLELASIVSELVAGLR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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