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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 02-MAY-2018
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae D39
- locus tag: SPD_1742 [new locus tag: SPD_RS09280 ]
- pan locus tag?: PNEUPAN003518000
- symbol: SPD_1742
- pan gene symbol?: mshD_2
- synonym:
- product: acetyltransferase, GNAT family protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPD_1742 [new locus tag: SPD_RS09280 ]
- symbol: SPD_1742
- product: acetyltransferase, GNAT family protein
- replicon: chromosome
- strand: -
- coordinates: 1736197..1736715
- length: 519
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP000410 (1736197..1736715) NCBI
- BioCyc: see SPD_RS09280
- MicrobesOnline: 2018594 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1742 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481ATGGAGTATGAATTGCTCATTAGGGAAGCAGAGCCCAAAGATGCAGCTGAATTAGTGGCC
TTTTTAAATCGTGTGAGTTTGGAGACAGACTTTACCAGCCTAGACGGAGATGGTATTCTC
TTGACTAGTGAGGAGATGGAAATATTCCTCAACAAGCAAGCTAGTTCGGACAATCAGATA
ACCTTACTTGCATTCTTAAATGGCAAAATTGCTGGTATTGTAAATATTACAGCTGATCAG
CGTAAGAGAGTCCGTCATATTGGAGATCTCTTCATTGTGATTGGAAAAAGATATTGGAAT
AATGGCTTGGGAAGTTTGTTGCTAGAAGAAGCGATAGAGTGGGCACAAGCAAGTGGCATT
CTGCGTCGTCTCCAACTGACTGTCCAAACTCGTAATCAAGCAGCAGTCCATCTTTATCAA
AAGCATGGCTTTGTCATTGAAGGTAGCCAAGAGCGTGGGGCATATATAGAAGAAGGGAAA
TTTATCGATGTTTACTTGATGGGTAAACTGATAGGTTAG60
120
180
240
300
360
420
480
519
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPD_1742 [new locus tag: SPD_RS09280 ]
- symbol: SPD_1742
- description: acetyltransferase, GNAT family protein
- length: 172
- theoretical pI: 4.88234
- theoretical MW: 19339
- GRAVY: -0.0511628
⊟Function[edit | edit source]
- TIGRFAM: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 43.6)Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 38.7)and 3 moreCell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides TDP-D-fucosamine acetyltransferase (TIGR02382; HMM-score: 25.8)Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs mycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 23.2)GNAT-family acetyltransferase TIGR03103 (TIGR03103; HMM-score: 11.7)
- TheSEED :
- Acetyltransferase, GNAT family
- PFAM: Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 64.3)and 7 moreAcetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 45.2)Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 42.1)Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 39.8)Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 31.4)Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 19.9)FR47; FR47-like protein (PF08445; HMM-score: 13.3)no clan defined GP46; Phage protein GP46 (PF07409; HMM-score: 13.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 1.78
- Cytoplasmic Membrane Score: 8.16
- Cellwall Score: 0.06
- Extracellular Score: 0.01
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002275
- TAT(Tat/SPI): 0.000239
- LIPO(Sec/SPII): 0.000276
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSEEMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNGLGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGKFIDVYLMGKLIG
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1742 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Jelle Slager, Rieza Aprianto, Jan-Willem Veening
Refining the Pneumococcal Competence Regulon by RNA Sequencing.
J Bacteriol: 2019, 201(13);
[PubMed:30885934] [WorldCat.org] [DOI] (I e)