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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_RS09140 [old locus tag: SPH_1875 ]
  • pan locus tag?: PNEUPAN003195000
  • symbol: SPH_RS09140
  • pan gene symbol?: epsJ_2
  • synonym:
  • product: glycosyltransferase family 2 protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_RS09140 [old locus tag: SPH_1875 ]
  • symbol: SPH_RS09140
  • product: glycosyltransferase family 2 protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1733976..1734881
  • length: 906
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_010380 (1733976..1734881) NCBI
  • BioCyc: SPH_RS09140 BioCyc
  • MicrobesOnline: see SPH_1875
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGAGTGAATTAATTAGTGTTGTGGTACCGATATACAATACGGGAAAATATTTAGTGGAG
    TGTGTCGAGCATATTCTGAAGCAAACCTATCAAAATATAGAAATTATTTTAGTTGATGAC
    GGTTCTACGGATAATTCTGGGGAAATTTGTGATGCTTTTATGATGCAAGATAATCGTGTG
    CGAGTATTGCATCAAGAAAATAAGGGGGGGGCAGCACAAGCTAAAAATATGGGGATTAGT
    GTAGCTAAGGGAGAGTACATCACGATTGTTGATTCAGATGATATCGTAAAAGAAAATATG
    ATTGAAACTCTTTATCAGCAAGTCCAAGAAAAGGATGCAGATGTTGTTATAGGGAATTAC
    TATAATTATGACGAAAGTGACGGGAATTTTTATTTTTATGTAACAGGGCAAGATTTTTGC
    GTCGAAGAATTAGCTATACAAGAAATTATGAACCGTCAAGCAGGAGATTGGAAATTCAAT
    AGCTCGGCCTTTATATTGCCGACATTTAAGTTGATTAAAAAAGAATTATTCAATGAAGTT
    CACTTTTCAAATGGTCGCCGCTTTGATGATGAAGCAACTATGCATCGCTTTTATCTTTTA
    GCCTCTAAAATCGTCTTTATAAACGATAATCTCTATCTGTATAGAAGACGTTCAGGAAGC
    ATCATGAGAACGGAATTTGATCTTTCCTGGGCAAGAGATATTGTTGAAGTGTTTTCTAAG
    AAAATATCGGATTGTGTCTTGGCTGGTTTGGATGTCTCCGTTCTGCGTATTCGATTTGTC
    AATCTTTTAAAAGATTATAAGCAAACTTTAGAATACCATCAATTAACAGATACTGAGGAA
    TATAAAGATATTTGTTTCAGATTAAAGTTGTTTTTTGATGCAGAACAAAGAAATGGTAAA
    AGTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    906

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_RS09140 [old locus tag: SPH_1875 ]
  • symbol: SPH_RS09140
  • description: glycosyltransferase family 2 protein
  • length: 301
  • theoretical pI: 4.64068
  • theoretical MW: 35010.5
  • GRAVY: -0.295349

⊟Function[edit | edit source]

  • reaction:
    EC 2.4.-.-?  ExPASy
  • TIGRFAM:
    poly-beta-1,6 N-acetyl-D-glucosamine synthase (TIGR03937; EC 2.4.1.-; HMM-score: 89)
    and 11 more
    putative glycosyltransferase, exosortase G-associated (TIGR03111; HMM-score: 59.6)
    mycofactocin system glycosyltransferase (TIGR03965; HMM-score: 55.1)
    colanic acid biosynthesis glycosyltransferase WcaA (TIGR04017; EC 2.4.-.-; HMM-score: 54.6)
    Unknown function Enzymes of unknown specificity transferase 2, rSAM/selenodomain-associated (TIGR04283; EC 2.-.-.-; HMM-score: 52.2)
    chitooligosaccharide synthase NodC (TIGR04242; EC 2.4.1.-; HMM-score: 48.4)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides rhamnosyltransferase (TIGR01556; EC 2.4.1.-; HMM-score: 43)
    hopene-associated glycosyltransferase HpnB (TIGR03469; HMM-score: 36.9)
    glycosyltransferase, TIGR04182 family (TIGR04182; HMM-score: 36.1)
    colanic acid biosynthesis glycosyltransferase WcaE (TIGR04009; EC 2.4.-.-; HMM-score: 32)
    hopanoid biosynthesis associated glycosyl transferase protein HpnI (TIGR03472; HMM-score: 14.7)
    selenium-dependent molybdenum hydroxylase system protein, YqeB family (TIGR03309; HMM-score: 13.2)
  • TheSEED: see SPH_1875
  • PFAM:
    GT-A (CL0110) Glycos_transf_2; Glycosyl transferase family 2 (PF00535; HMM-score: 138.2)
    and 6 more
    Glyco_tranf_2_3; Glycosyltransferase like family 2 (PF13641; HMM-score: 65)
    Glyco_tranf_2_2; Glycosyltransferase like family 2 (PF10111; HMM-score: 51.5)
    Glyco_tranf_2_4; Glycosyl transferase family 2 (PF13704; HMM-score: 24.9)
    Glyco_transf_21; Glycosyl transferase family 21 (PF13506; HMM-score: 18.7)
    ATP_synthase (CL0255) T3SS_SCTL; Type 3 secretion system stator protein (PF06635; HMM-score: 17.2)
    GT-A (CL0110) Glyco_trans_2_3; Glycosyl transferase family group 2 (PF13632; HMM-score: 11.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.5846
    • Cytoplasmic Membrane Score: 0.1591
    • Cell wall & surface Score: 0.002
    • Extracellular Score: 0.2542
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006863
    • TAT(Tat/SPI): 0.0001
    • LIPO(Sec/SPII): 0.000751
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTDNSGEICDAFMMQDNRVRVLHQENKGGAAQAKNMGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVEVFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDAEQRNGKS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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