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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_RS09095 [old locus tag: SPH_1866 ]
  • pan locus tag?: PNEUPAN003185000
  • symbol: asp5
  • pan gene symbol?: asp5
  • synonym:
  • product: accessory Sec system protein Asp5

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_RS09095 [old locus tag: SPH_1866 ]
  • symbol: asp5
  • product: accessory Sec system protein Asp5
  • replicon: chromosome
  • strand: -
  • coordinates: 1723528..1723752
  • length: 225
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_010380 (1723528..1723752) NCBI
  • BioCyc: SPH_RS09095 BioCyc
  • MicrobesOnline: see SPH_1866
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGATTGAAATACTAATTGTTTTAGCTATTATCCTATCTCTTGCTTTGATTGTATTGGTA
    ACTATACAACCCCGTCAAAATCAACTATTTTCCATGGATGCCACTAGTAATATTGGTAAA
    CCAAGCTACTGGCAGAGCAACACCTTGGTCAAGGTGCTCACTTTATTGGTGAGTTTGGCT
    TTATTTGTTCTACTATTAACCTTTATGGTGATTACTTATAAATAA
    60
    120
    180
    225

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_RS09095 [old locus tag: SPH_1866 ]
  • symbol: Asp5
  • description: accessory Sec system protein Asp5
  • length: 74
  • theoretical pI: 9.86564
  • theoretical MW: 8292.12
  • GRAVY: 1.24865

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking preprotein translocase, SecG subunit (TIGR00810; HMM-score: 16.9)
    Metabolism Energy metabolism Electron transport cytochrome c oxidase, subunit II (TIGR02866; EC 1.9.3.1; HMM-score: 13.9)
    and 4 more
    Metabolism Transport and binding proteins Other rim ABC transporter (TIGR01257; HMM-score: 9)
    Cellular processes Cellular processes Cell division cell division protein FtsL (TIGR02209; HMM-score: 5.2)
    Cell structure Cell envelope Surface structures prepilin-type N-terminal cleavage/methylation domain (TIGR02532; HMM-score: 4.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking prepilin-type N-terminal cleavage/methylation domain (TIGR02532; HMM-score: 4.3)
  • TheSEED: see SPH_1866
  • PFAM:
    no clan defined Asp5; Accessory secretory protein Sec, Asp5 (PF17000; HMM-score: 101.3)
    and 4 more
    SecG; Preprotein translocase SecG subunit (PF03840; HMM-score: 20.7)
    Cation_ATPase_C; Cation transporting ATPase, C-terminus (PF00689; HMM-score: 12)
    Thioredoxin (CL0172) OST3_OST6; OST3 / OST6 family, transporter family (PF04756; HMM-score: 9.9)
    no clan defined MRAP; Melanocortin-2 receptor accessory protein family (PF15183; HMM-score: 8.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9987
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0013
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.021164
    • TAT(Tat/SPI): 0.000503
    • LIPO(Sec/SPII): 0.048449
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIEILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYWQSNTLVKVLTLLVSLALFVLLLTFMVITYK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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