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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae JJA
- locus tag: SPJ_1293 [new locus tag: SPJ_RS06425 ]
- pan locus tag?: PNEUPAN002720000
- symbol: SPJ_1293
- pan gene symbol?: glnH_3
- synonym:
- product: ABC transporter substrate-binding protein - glutamine-binding protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPJ_1293 [new locus tag: SPJ_RS06425 ]
- symbol: SPJ_1293
- product: ABC transporter substrate-binding protein - glutamine-binding protein
- replicon: chromosome
- strand: -
- coordinates: 1242311..1242997
- length: 687
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP000919 (1242311..1242997) NCBI
- BioCyc: see SPJ_RS06425
- MicrobesOnline: 7479554 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1226 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661GTGGCAACCAGTCCTGACTATGCACCCTTTGAATTTCAATCATTGGTTGATGGAAAGAAC
CAGGTAGTCGGTGCAGACATCGACATGGCTCAGGCTATCGCTGATGAACTTGGGGTTAAG
TTGGAAATCTCAAGCATGAGTTTTGACAATGTTTTGACCAGTCTTCAAACTGGTAAGGCT
GACCTAGCAGTTGCAGGAATTAGTGCTACTGACGAGAGAAAAGAAGTCTTTGATTTTTCA
ATCCCATACTATGAAAACAAGATTAGTTTCTTGGTTCGTAAGGCTGATGTGGAAAAATAC
AAGGATTTAACTAGCCTAGAAAGTGCTAATATTGCAGCCCAAAAAGGGACTGTTCCAGAA
TCAATGGTCAAGGAACAATTGCCAAAAGCTCAATTAACTTCCCTAACTAATATGGGTGAA
GCAGTCAATGAATTGCAGGCTGGAAAAGTAGATGCTGTTCATATGGATGAGCCTGTTGCA
CTTAGTTATGCTGCTAAAAACGCTGGCTTAGCTGTCGCAACTGTCAGCTTGAAGATGAAG
GACGGCGACGCCAATGCCGTTGCTCTTAGAAAAAATAGTGATGATTTGAAAGAAGTGGTA
GACAAGGTCATCCAAAAACTTAAGGATGAAGGAATTTACCAAAGCTATCTTGAAAAAGCA
GCAAGTCTAACTGAAGTTGAAGAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPJ_1293 [new locus tag: SPJ_RS06425 ]
- symbol: SPJ_1293
- description: ABC transporter substrate-binding protein - glutamine-binding protein
- length: 228
- theoretical pI: 4.29592
- theoretical MW: 24632.7
- GRAVY: -0.208772
⊟Function[edit | edit source]
- TIGRFAM: Transport and binding proteins Amino acids, peptides and amines lysine-arginine-ornithine-binding periplasmic protein (TIGR01096; HMM-score: 149)and 3 moreextracellular substrate-binding orphan protein, GRRM family (TIGR04262; HMM-score: 56.7)Transport and binding proteins Amino acids, peptides and amines ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB (TIGR02995; HMM-score: 53)quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein (TIGR03871; HMM-score: 32.1)
- TheSEED :
- Amino acid ABC transporter, amino acid-binding/permease protein
- PFAM: PBP (CL0177) SBP_bac_3; Bacterial extracellular solute-binding proteins, family 3 (PF00497; HMM-score: 187.2)and 4 moreLig_chan-Glu_bd; Ligated ion channel L-glutamate- and glycine-binding site (PF10613; HMM-score: 39.2)NMT1_2; NMT1-like family (PF13379; HMM-score: 14)B_GA (CL0598) GA-like; GA-like domain (PF17573; HMM-score: 12.9)PBP (CL0177) SBP_bac_5; Bacterial extracellular solute-binding proteins, family 5 Middle (PF00496; HMM-score: 12.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.006195
- TAT(Tat/SPI): 0.000358
- LIPO(Sec/SPII): 0.00031
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGKADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGTVPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATVSLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulators: ArgR2* (activation (repression)) regulon, AhrC* (activation (repression)) regulon, ArgR1* (activation (repression)) regulon
ArgR2* (TF) important in Arginine biosynthesis, Arginine degradation; RegPrecise AhrC* (TF) important in Arginine biosynthesis, Arginine degradation; RegPrecise ArgR1* (TF) important in Arginine biosynthesis, Arginine degradation; RegPrecise
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1226 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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