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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN034183
  • locus tag: SPN034183_RS02035 [old locus tag: SPN034183_03790 ]
  • pan locus tag?: PNEUPAN001212000
  • symbol: cbpC
  • pan gene symbol?: cbpF
  • synonym: cbpJ
  • product: choline-binding protein CbpC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN034183_RS02035 [old locus tag: SPN034183_03790 ]
  • symbol: cbpC
  • product: choline-binding protein CbpC
  • replicon: chromosome
  • strand: +
  • coordinates: 370976..371998
  • length: 1023
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_021028 (370976..371998) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0345 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAAGCTTTTGAAAAAAATGATGCAAGTCGCATTAGCAGTCTTTTTCTTTGGTTTGCTA
    GCTACAAATACGGTATTTGCGAATACCACAGGTGGCCGATTTGTTGATAAGGATAATAGA
    AAATATTATGTAAAAGATGATCATAAAGCAATCTATTGGCATAAAATAGACGGTAAAACT
    TACTATTTTGGTGATATTGGAGAGATGGTTGTCGGTTGGCAATACTTAGAAATTCCTGGA
    ACAGGTTATCGTGATAATTTATTCGATAACCAACCAGTTAATGAAATTGGCCTTCAGGAG
    AAGTGGTACTATTTTGGACAAGATGGTGCTTTGCTAGAACAAACAGATAAACAAGTACTA
    GAGGCAAAAACGTCTGAAAATACAGGAAAAGTATACGGTGAACAATATTCTCTATCTGCT
    GAAAAGAGAACTTATTATTTTGATAATAATTATGCTGTAAAGACAGGCTGGATTTATGAA
    GAGGGTCATTGGTATTATTTAAATAAGCTAGGAAATTTTGGCGATGATTCTTACAATCCA
    CTACCAATTGGTGAAGTTGCTAAGGGTTGGACTCAAGATTTTCATGTTACTATTGACATT
    GATAGAAGCAAACCTGCTCCATGGTACTACCTAGATGCTTCAGGTAAGATGCTTACAGAT
    TGGCAAAAAGTAAACGGAAAATGGTATTATTTTGGCTCCTCTGGTTCTATGGCAACAGGT
    TGGAAATATGTACGAGGCAAATGGTATTACTTAGATAATAAAAATGGTGATATGAAAACA
    GGATGGCAATACCTTGGTAACAAGTGGTACTACCTCCGTTCATCAGGAGCTATGGTAACT
    GGCTGGTATCAAGATGGTTCAACTTGGTACTATTTAGATGCTGAAAATGGTGATATGAAA
    ATAGGTTGGACAAAAGTAAATGGAAAATGGTATTATCTCAATTCCTCTGGAGCAATGGTT
    ACAGGTAGTCAAACTATCGATGGTAAAGTTTATAACTTCGCTTCATCTGGTGAGTGGATT
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1023

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN034183_RS02035 [old locus tag: SPN034183_03790 ]
  • symbol: CbpC
  • description: choline-binding protein CbpC
  • length: 340
  • theoretical pI: 6.96972
  • theoretical MW: 39497.9
  • GRAVY: -0.647941

⊟Function[edit | edit source]

  • TIGRFAM:
    glucan-binding repeat (TIGR04035; HMM-score: 79.5)
  • TheSEED: see SPN034183_03790
  • PFAM:
    Choline_binding (CL0694) Choline_bind_3; Choline-binding repeat (PF19127; HMM-score: 156.6)
    Choline_bind_1; Putative cell wall binding repeat (PF01473; HMM-score: 132.5)
    and 3 more
    Choline_bind_2; Choline-binding repeat (PF19085; HMM-score: 26.8)
    no clan defined DUF5754; Family of unknown function (DUF5754) (PF19058; HMM-score: 14.2)
    CoV_S1_C; Coronavirus spike glycoprotein S1, C-terminal (PF19209; HMM-score: 10.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.09
    • Cellwall Score: 0.18
    • Extracellular Score: 9.72
    • Internal Helix: 1
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.0013
    • Cell wall & surface Score: 0.1081
    • Extracellular Score: 0.8906
  • SignalP: Signal peptide SP(Sec/SPI) length 27 aa
    • SP(Sec/SPI): 0.994543
    • TAT(Tat/SPI): 0.001442
    • LIPO(Sec/SPII): 0.002842
    • Cleavage Site: CS pos: 27-28. VFA-NT. Pr: 0.9743
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000771086 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKLLKKMMQVALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYVKDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKWYYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYSLSAEKRTYYFDNNYAVKTGWIYEEGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKMLTDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSGAMVTGWYQDGSTWYYLDAENGDMKIGWTKVNGKWYYLNSSGAMVTGSQTIDGKVYNFASSGEWI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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