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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 27-FEB-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_01032 [new locus tag: SPNA45_RS05785 ]
  • pan locus tag?: PNEUPAN001607000
  • symbol: SPNA45_01032
  • pan gene symbol?: moeB
  • synonym:
  • product: HesA/MoeB/ThiF family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_01032 [new locus tag: SPNA45_RS05785 ]
  • symbol: SPNA45_01032
  • product: HesA/MoeB/ThiF family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1029708..1030721
  • length: 1014
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGTATGGAGTGAGGAAACTTATTGTCGCTGATTACGATATAATAGAACCATCAAATTTA
    AATAGGCAAATTCTTTATACAGAGTCGGATGTTGGTAAGGAGAAGATTAATGTTCTTTCT
    GAAAAAATACACAAGTATAATTCAGATGTTCAGGTAGTACCTATTTCTATTAAAGTTTCT
    TCATTAGAAGAATTAGAAAAAATTGTTGCGGAATATGGGAGTATAGATTTTATCGTTAAA
    GCAATTGATACGCCCATTGATATTATAAAAATTGTCAATCAATTTGCTGTATCGCATAAG
    ATATCCTACATATCAGGAGGGTTTAATGGATGCTATCTTATTATTGATAATATATATATC
    CCTACCATCGGTTCTTGCTTTGGTTGTCGGAATATAAACAAAGATATAAATAAGTACACT
    TTATCTGATAAGACAAAGTGGCCGACTACACCAGAGATGCCTGCTATTTTGGGAGGGATA
    ATGACTAATTTAATAATTAAAATATTTCTGGGATGTTATAATGAAATCCTAATAGATAAC
    GCTTACGTTTATAATATGAGAAATCATGCTCTAAGTCAAAAAAAATATGTTCTGGAAAAC
    GGAGAATGTCCAATTTGTAAAAAAAATAATAAAGTGAAAGATAACAATATTAGAGCGAAA
    ACATTTATTCGTTCAGTTTGTTTTTGCTTATTATCAGGAGGAGTAGCTTTTTTATCTGCT
    ATTGGGCAGTTCACTGTTATAGAAACACAATTAATAGTATTGTTCTTGGGTATTATTTTT
    GCTATATATTATGCTTACTACAATAAAAATATTCAAACATCATTGGAAAATATAGTATGG
    CTTTTTTCATCGTTTGAGATTTTATTTTTGCTTGTTAATTTTAGAACATTTATTCAGTTA
    CCAGTGGATATTTTTATTGGTATGATAATATTTTTAATGCTGTGGATATTTATTATGTTA
    GGTATAGTGTGTCTTAGTTATTATATAACTTTATTATTTAGCAAGGAGGCTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1014

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_01032 [new locus tag: SPNA45_RS05785 ]
  • symbol: SPNA45_01032
  • description: HesA/MoeB/ThiF family protein
  • length: 337
  • theoretical pI: 7.89906
  • theoretical MW: 38428.1
  • GRAVY: 0.437092

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine thiazole biosynthesis adenylyltransferase ThiF (TIGR02356; EC 2.7.7.73; HMM-score: 59.3)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine thiamine biosynthesis protein ThiF (TIGR02354; HMM-score: 50.3)
    and 4 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Molybdopterin molybdopterin synthase sulfurylase MoeB (TIGR02355; HMM-score: 45)
    ubiquitin-activating enzyme E1 (TIGR01408; HMM-score: 29.7)
    PRTRC system ThiF family protein (TIGR03736; HMM-score: 15.2)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides beta-aspartyl peptidase (TIGR01975; EC 3.4.19.5; HMM-score: 13.4)
  • TheSEED: data available for D39, TIGR4
  • PFAM:
    NADP_Rossmann (CL0063) ThiF; ThiF family (PF00899; HMM-score: 94.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0082
    • Cytoplasmic Membrane Score: 0.8679
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.1237
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002954
    • TAT(Tat/SPI): 0.000186
    • LIPO(Sec/SPII): 0.000386
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCM08317 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSEKIHKYNSDVQVVPISIKVSSLEELEKIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLIIDNIYIPTIGSCFGCRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCYNEILIDNAYVYNMRNHALSQKKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLLSGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQTSLENIVWLFSSFEILFLLVNFRTFIQLPVDIFIGMIIFLMLWIFIMLGIVCLSYYITLLFSKEA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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