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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 14-DEC-2023
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae SPNA45
- locus tag: SPNA45_RS14220 [old locus tag: SPNA45_01691 ]
- pan locus tag?: PNEUPAN001120000
- symbol: SPNA45_RS14220
- pan gene symbol?: cps2A
- synonym: cps4A
- product: LCP family protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPNA45_RS14220 [old locus tag: SPNA45_01691 ]
- symbol: SPNA45_RS14220
- product: LCP family protein
- replicon: chromosome
- strand: -
- coordinates: 1724950..1725645
- length: 696
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_018594 (1724950..1725645) NCBI
- BioCyc:
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0315 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661ATGACTGTCAATCGAGATACCAAGAAAATCCTCTTGACCACAACGCCGCGTGATGCCTAT
GTACCAATTGCAGATGGTGGAAATAATCAAAAAGATAAATTGACTCATGCGGGCATTTAT
GGAGTTGATTCGTCCATTCACACCTTAGAAAATCTCTATGGAGTGGATATCAATTACTAT
GTACGATTGAACTTCACTTCGTTTTTGAAATTGATTGATTTGTTGGATGGAATTGATGTT
TATAATGATCAAGAATTTACTGCCCATACGAATGGAAAGTATTACCCTGAAGGCAATGTT
CATCTTGATTCAGAACAGGCTCTCGGTTTTGTTCGTGAGCGCTACTCCCTAGCAGATGGC
GATCGTGACCGCGGGCGCAATCAACAAAAGGTGATTGTGGCTATCCTTCAAAAATTAACG
TCAACCGAAGAACTGAAAAATTATAGTACGATCATTGATAGCTTGCAAGATTCTATCCAA
ACAAATATGCCGATTGAGACTATGATAGATTTAGTGAATACTCAGTTGGAAAGTGGAGGG
AATTATAAAGTAAATTCTCAAGATTTAAAAGGGACAGGTCGGATGGATCTTCCTTCTTAT
GCAATGCCAGACAGTAACCTCTATGTGATGGAAATAGATGATAGTAGTTTAGCTGTAGTT
AAAGCAGCTATACAGGATGTGATGAAAGGTAGATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPNA45_RS14220 [old locus tag: SPNA45_01691 ]
- symbol: SPNA45_RS14220
- description: LCP family protein
- length: 231
- theoretical pI: 4.62307
- theoretical MW: 25897.9
- GRAVY: -0.451948
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions Other cell envelope-related function transcriptional attenuator common domain (TIGR00350; HMM-score: 83.4)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: no clan defined LytR_cpsA_psr; LytR_cpsA_psr family (PF03816; HMM-score: 124)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 1.05
- Cytoplasmic Membrane Score: 8.78
- Cellwall Score: 0.08
- Extracellular Score: 0.09
- Internal Helices: 0
- DeepLocPro: Extracellular
- Cytoplasmic Score: 0.0001
- Cytoplasmic Membrane Score: 0.0046
- Cell wall & surface Score: 0.0005
- Extracellular Score: 0.9948
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.023252
- TAT(Tat/SPI): 0.001481
- LIPO(Sec/SPII): 0.004444
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000217814 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MTVNRDTKKILLTTTPRDAYVPIADGGNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLDGIDVYNDQEFTAHTNGKYYPEGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTSTEELKNYSTIIDSLQDSIQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSYAMPDSNLYVMEIDDSSLAVVKAAIQDVMKGR
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0315 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Judy K Morona, David C Miller, Renato Morona, James C Paton
The effect that mutations in the conserved capsular polysaccharide biosynthesis genes cpsA, cpsB, and cpsD have on virulence of Streptococcus pneumoniae.
J Infect Dis: 2004, 189(10);1905-13
[PubMed:15122528] [WorldCat.org] [DOI] (P p)