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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC03630 [new locus tag: SPNOXC_RS01970 ]
  • pan locus tag?: PNEUPAN001225000
  • symbol: aliA
  • pan gene symbol?: aliA
  • synonym:
  • product: Oligopeptide ABC transporter

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC03630 [new locus tag: SPNOXC_RS01970 ]
  • symbol: aliA
  • product: Oligopeptide ABC transporter
  • replicon: chromosome
  • strand: +
  • coordinates: 355488..356408
  • length: 921
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    TTGAATGGACAAACTGGAGCAAGCAAAATCTTACGTAATCTCTTTGTTCCACCAACATTT
    GTTCAAGCAGATGGTAAAAACTTTGGCGATATGGTCAAAGAGAAATTGGTCACTTATGGG
    GATGAATGGAAGGATGTTAATCTTGCAGATTCTCAGGATGGTCTTTACAATCCAGAAAAA
    GCCAAGGCTGAATTTGCTAAAGCTAAATTAGCCTTACAAGCAGAAGGAGTCCAATTCCCA
    ATTCATTTAGATATGCCAGTTGACCAGACAGCAACTACAAAAGTTCAGCGCGTCCAATCT
    ATGAAACAATCCTTGGAAGCAACTTTAGGAACTGATAATGTCATTATTGATATCCAACAA
    CTACAAAAAGACGAAGTAAACGATATTACATATTTTGCTGAAAACGCTGCTGGCGAAGAC
    TGGGATTTATCAGATAATGTCGGTTGGGGTCCAGACTTTGCCGATCCATCAACCTACCTT
    GATATCATCAAACCATCTGTAGGAGAAAGTACTAAAACATATTTAGGGTTTGACTCAGGG
    GAAGATAATGTAGCTGCTAAAAAAGTAGGTCTATATGACTACGAAAAATTGGTTACTGAG
    GCTGGTGATGAGGCTACAGATGTTGCTAAACGCTATGATAAATACGCTGCAGCCCAAGCT
    TGGTTGACAGATAGTGCTTTGATTATTCCAACTACATCTCGTACAGGGCGTCCAATCTTG
    TCTAAGATGGTACCATTTACAATACCATTTGCATTGTCAGGAAATAAAGGTACAAGTGAA
    CCAATCTTATATAAATACTTGGAACTTCAAGACAAGGCAGTCACTGTAGATGAATACCAA
    AAAGCTCAGGAAAAATGGATGAAAGAAAAAGAAGAGTCTAATAAAAAGGCTCAAGAAGAT
    CTCGCAAAACATGTGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    921

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPNOXC03630 [new locus tag: SPNOXC_RS01970 ]
  • symbol: AliA
  • description: Oligopeptide ABC transporter
  • length: 306
  • theoretical pI: 4.4989
  • theoretical MW: 33981.9
  • GRAVY: -0.556209

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)
    Membrane Transport ABC transporters ABC transporter oligopeptide (TC 3.A.1.5.1)  Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)
  • PFAM:

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.53
    • Cellwall Score: 8.75
    • Extracellular Score: 0.7
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.037238
    • TAT(Tat/SPI): 0.0015
    • LIPO(Sec/SPII): 0.007891
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW32022 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVTYGDEWKDVNLADSQDGLYNPEKAKAEFAKAKLALQAEGVQFPIHLDMPVDQTATTKVQRVQSMKQSLEATLGTDNVIIDIQQLQKDEVNDITYFAENAAGEDWDLSDNVGWGPDFADPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRYDKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQDKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]

J P Claverys, B Grossiord, G Alloing
Is the Ami-AliA/B oligopeptide permease of Streptococcus pneumoniae involved in sensing environmental conditions?
Res Microbiol: 2000, 151(6);457-63
[PubMed:10961459] [WorldCat.org] [DOI] (P p)
A R Kerr, P V Adrian, S Estevão, R de Groot, G Alloing, J-P Claverys, T J Mitchell, P W M Hermans
The Ami-AliA/AliB permease of Streptococcus pneumoniae is involved in nasopharyngeal colonization but not in invasive disease.
Infect Immun: 2004, 72(7);3902-6
[PubMed:15213133] [WorldCat.org] [DOI] (P p)
Fauzy Nasher, Manfred Heller, Lucy J Hathaway
Streptococcus pneumoniae Proteins AmiA, AliA, and AliB Bind Peptides Found in Ribosomal Proteins of Other Bacterial Species.
Front Microbiol: 2017, 8;2688
[PubMed:29379482] [WorldCat.org] [DOI] (P e)