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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 25-OCT-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NU83127
  • locus tag: SPNU_0655 [new locus tag: EL277_RS03490 ]
  • pan locus tag?: PNEUPAN001607000
  • symbol: thiF
  • pan gene symbol?: moeB
  • synonym:
  • product: Sulfur carrier protein ThiS adenylyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNU_0655 [new locus tag: EL277_RS03490 ]
  • symbol: thiF
  • product: Sulfur carrier protein ThiS adenylyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 670121..670756
  • length: 636
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTATGGAGTGAGGAAACTTATTGTCGCTGATTACGATATAATAGAACCATCAAATTTA
    AATAGGCAAATTCTTTATACAGAGTCGGATGTTGGTAAGGAGAAGATTAATGTTCTTTCT
    GAAAAAATACACAAGTATAATTCAGATGTTCAGGTAGTACCTATTTCTATTAAAGTTTCT
    TCAGTAGAAGAATTAGAAAAAATTGTTGCGGAATATGGGAGTATAGATTTTATCGTTAAA
    GCAATTGATACGCCCATTGATATTATAAAAATTGTCAATCAATTTGCTGTATCGCATAAG
    ATATCCTACATATCAGGAGGGTTTAATGGATGCTATCTTATTATTGATAATATATATATC
    CCTACCATCGGTTCTTGCTTTGGTTGTCGGAATATAAACAAAGATATAAATAAGTACACT
    TTATCTGATAAGACAAAGTGGCCGACTACACCAGAGATGCCTGCTATTTTGGGAGGGATA
    ATGACTAATTTAATAATTAAAATATTTCTGGGATGTTATAATGAAATCCTAATAGATAAC
    GCTTACGTTTATAATATGAGAAATCATGCTCTAAGTCAAGAAAAATATGTTCTGGAAAAC
    GGAGAATGTCCAATTTGTAAAAAAATAATAAAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    636

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNU_0655 [new locus tag: EL277_RS03490 ]
  • symbol: ThiF
  • description: Sulfur carrier protein ThiS adenylyltransferase
  • length: 211
  • theoretical pI: 6.74939
  • theoretical MW: 23864.7
  • GRAVY: 0.0530806

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine thiazole biosynthesis adenylyltransferase ThiF (TIGR02356; EC 2.7.7.73; HMM-score: 60.9)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine thiamine biosynthesis protein ThiF (TIGR02354; HMM-score: 51.7)
    and 4 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Molybdopterin molybdopterin synthase sulfurylase MoeB (TIGR02355; HMM-score: 46.7)
    ubiquitin-activating enzyme E1 (TIGR01408; HMM-score: 31.6)
    PRTRC system ThiF family protein (TIGR03736; HMM-score: 16.6)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides beta-aspartyl peptidase (TIGR01975; EC 3.4.19.5; HMM-score: 16.2)
  • TheSEED: data available for D39, TIGR4
  • PFAM:
    NADP_Rossmann (CL0063) ThiF; ThiF family (PF00899; HMM-score: 95.9)
    and 1 more
    EspA_CesA (CL0628) T3SchapCesA; Type III secretion system filament chaperone CesA (PF11439; HMM-score: 10.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9174
    • Cytoplasmic Membrane Score: 0.0447
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0378
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003086
    • TAT(Tat/SPI): 0.000206
    • LIPO(Sec/SPII): 0.000399
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG34546 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSEKIHKYNSDVQVVPISIKVSSVEELEKIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLIIDNIYIPTIGSCFGCRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCYNEILIDNAYVYNMRNHALSQEKYVLENGECPICKKIIK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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