From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-NOV-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Taiwan19F-14
  • locus tag: SPT_RS02670 [old locus tag: SPT_0535 ]
  • pan locus tag?: PNEUPAN001382000
  • symbol: SPT_RS02670
  • pan gene symbol?: endoD
  • synonym:
  • product: bacterial Ig-like domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPT_RS02670 [old locus tag: SPT_0535 ]
  • symbol: SPT_RS02670
  • product: bacterial Ig-like domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 500080..505020
  • length: 4941
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    ATGAAGAATCCATTTTTTGAAAGACGTTGTCGTTACAGTATTCGTAAGTTATCAGTAGGA
    GCCTGCTCGCTGATGATTGGTGCTGTTTTATTTGCTGGTCCAGCCTTGGCTGAAGAAACT
    GCAGTTCCTGAAAATAGCGGAGCTAATACAGAGCTTGTTTCAGGAGAGAGTGAGCATTCG
    ACCAATGAAGCTGATAAGCAGAATGAAGGGGAACATACTAGAGAAAACAAGCTAGAAAAG
    GCAGAAGGAGTAGCGACAGCATCTGAAACTGCAGAAGCAGCTAGCGCAGCTAAACCAGAG
    GAAAAAGCAAGTGAGGTGGTTGCAGAAACACCATCTGCAGAAGCAAAACCTAAGTCTGAC
    AAGGAAACAGAAGCAAAGCCCGAAGCAACTAACCAAGGGGATGAGTCTAAGCCAGCAGCC
    GAAGCTAATAAGACTGAAAAAGAAGTCCAGCCAGATGTCCCTAAAAATACAGAAAAAACA
    TTAAAACCAAAGGAAATCAAATTTAATTCTTGGGAAGAATTGTTAAAATGGGAACCAGGT
    GCTCGTGAAGATGATGCTATTAACCGCGGATCTGTTGTCCTCGCTTCACGTCGGACAGGT
    CATTTAGTCAATGAAAAAGCTAGCAAGGAAGCAAAAGTTCAAGCCTTATCAAACACCAAT
    TCTAAAGCAAAAGACCATGCTTCTGTTGGTGGAGAAGAGTTCAAGGCCTATGCTTTTGAC
    TATTGGCAATATCTAGATTCAATGGTCTTCTGGGAAGGTCTCGTACCAACTCCTGACGTT
    ATTGATGCAGGTCACCGTAACGGGGTTCCTGTATACGGTACACTCTTCTTCAACTGGTCT
    AATAGTATTGCAGATCAAGAAAGATTTGCTGAAGCTTTGAAGCAAGACGCAGATGGTAGC
    TTCCCAATTGCCCGTAAATTGGTAGACATGGCCAAGTATTATGGCTATGATGGCTATTTC
    ATCAACCAAGAAACAACTGGAGATTTGGTTAAACCTCTTGGAGAAAAGATGCGCCAGTTT
    ATGCTCTATAGCAAGGAATATGCTGCTAAGGTAAACCATCCAATCAAGTATTCTTGGTAC
    GATGCCATGACCTATAACTATGGACGTTACCATCAAGATGGTTTGGGAGAATACAACTAC
    CAATTCATGCAACCAGAAGGAGATAAGGTTCCGGCAGATAACTTCTTTGCTAACTTTAAC
    TGGGATAAGGCTAAAAATGATTACACTATTGCAACTGCCAACTGGATTGGTCGTAATCCT
    TATGATGTATTTGCAGGTTTGGAATTGCAACAGGGTGGTTCCTACAAGACAAAGGTTAAG
    TGGAATGACATTTTAGACGAAAATGGGAAATTGCGCCTTTCTCTTGGTTTATTTGCCCCA
    GATACCATTACAAGTTTAGGAAAAACTGGTGAAGATTATCATAAAAATGAAGATATCTTC
    TTTACAGGTTATCAAGGAGACCCCACTGGCCAAAAACCAGGTGACAAAGATTGGTATGGT
    ATTGCTAACCTAGTTGCGGACCGTACGCCAGCGGTAGGTAATACTTTTACTACTTCTTTT
    AATACAGGTCATGGTAAAAAATGGTTCGTAGATGGTAAGGTTTCTAAGGATTCTGAGTGG
    AATTATCGTTCAGTATCAGGTGTTCTTCCAACATGGCGCTGGTGGCAGACTTCAACAGGG
    GAAAAACTTCGTGCAGAATATGATTTTACAGATGCCTATAATGGCGGAAATTCCCTTAAA
    TTCTCTGGTGATGTAGCCGGTAAGACAGATCAGGATGTGAGACTTTATTCTACTAAGTTA
    GAAGTAACTGAGAAGACCAAACTTCGTGTTGCCCACAAGGGAGGAAAAGGTTCTAAAGTT
    TATATGGCATTCTCTACAACTCCAGACTACAAATTCGATGATGCAGATGCATGGAAAGAG
    CTAACCCTTTCTGACAACTGGACAAATGAAGAATTTGATCTTAGCTCACTAGCGGGTAAA
    ACCATCTATGCAGTCAAACTATTTTTCGAGCATGAAGGTGCTGTAAAAGATTATCAGTTT
    AACCTAGGACAATTAACTATCTCGGACAATCACCAAGAGCCACAATCGCCGACAAGCTTT
    TCTGTAGTGAAACAATCTCTTAAAAATGCCCAAGAAGCGGAAGCAGTTGTGCAATTTAAA
    GGCAACAAGGATGCAGATTTCTATGAAGTTTATGAAAAAGATGGAGACAGCTGGAAATTA
    CTAACTGGCTCATCTTCTACAACTATTTATCTACCAAAAGTTAGCCGCTCAGCAAGTGCT
    CAGGGTACAACTCAAGAACTGAAGGTTGTAGCAGTCGGTAAAAATGGAGTTCGTTCAGAA
    GCTGCAACCACAACCTTTGATTGGGGTATGACTGTAAAAGATACCAGCCTACCAAAACCA
    CTAGCTGAAAATATCGTTCCAGGTGCAACAGTTATTGATAGTACTTTCCCTAAGACTGAA
    GGTGGAGAAGGTATTGAAGGTATGTTGAACGGTACCATTACTAGCTTGTCAGATAAATGG
    TCTTCAGCTCAGTTGAGTGGTAGTGTGGATATTCGTTTGACCAAGCCACGTACCGTTGTT
    AGATGGGTCATGGATCATGCAGGAGCTGGTGGTGAGTCTGTTAACGATGGCTTGATGAAC
    ACTAAAGACTTTGACCTTTATTATAAAGATGCAGATGGTGAGTGGAAGCTAGCTAAGGAA
    GTCCGTGGTAACAAAGCACACGTGACAGATATCACTCTTGATAAACCAATCACTGCTCAA
    GACTGGCGCTTGAATGTTGTCACTTCTGACAATGGAACTCCATGGAAGGCTATTCGTATC
    TATAACTGGAAAATGTATGAAAAGCTTGATACTGAGAGTGTCAATATTCCGATGGCCAAG
    GCTGCAGCCCGTTCTCTAGGCAATAACAAGGTACAAGTTGGCTTTGCAGATGTACCGGCT
    GGAGCAACTATTACCGTTTATGATAATCCAAATTCTCAAACTCCGCTCGCAACCTTGAAG
    AGCGAAGTTGGAGGAGACCTAGCAAGTGCACCATTGGATTTGACAAATCAATCTGGTCTT
    CTTTATTATCGTACCCAGTTGCCAGGCAAGGAAATTAGTAATGTCCTAGCAGTTTCCGTT
    CCAAAAGATGACAGAAGAATCAAGTCAGTCAGCCTAGAAACAGGACCTAAGAAAACAAGC
    TACGCCGAAGGGGAGGATTTGGACCTTAGAGGTGGTGTTCTTCGAGTTCAGTATGAAGGA
    GGAACTGAGGACGAACTCATTCGCCTAACTCACGCAGGTGTATCAGTATCAGGTTTTGAT
    ACGCATCATAAGGGAGAACAGAATCTTACTCTCCAATATTTGGGACAACCAGTAAATGCT
    AATTTGTCAGTGACTGTCACTGGCCAAGATGAAGCAAGTCCGAAAACTATTTTGGGAATT
    GAAGTAAGTCAGGAACCGAAAAAAGATTACCTAGTTGGTGATAGCTTAGACTTGTCTGAA
    GGACGCTTTGCAGTGGCTTATAGCAATGACACCATGGAAGAACATTCCTTTACTGATGAG
    GGAGTTGAAATTTCTGGTTACGATGCTCAAAAGACTGGTCGTCAAACCTTGACGCTTCGT
    TACCAAGGTCATGAAGTCAACTTTGATGTTTTGGTATCTCCAAAAGCAGCATTGAACGAT
    GAGTACCTCAAACAAAAATTAGCAGAAGTTGAAGCTGCTAAGAACAAGGTGGTCTATAAC
    TTTGCTTCACCAGAAGTAAAAGAAGCTTTCTTGAAAGCAATTGAAGCGGCCGAACAAGTG
    TTGAAAGACCATGAAACTAGCACCCAAGATCAAGTCAATGACCGACTTAATAAATTGACA
    GAAGCTCATAAAGCTCTGAATGGTCAAGAGAAATTTAAGGAAGAAAAGACAGAGCTTGAT
    CGTTTAACAGGTGAGGTTCAAGAACTCTTGGCTGCCAAACCAAACCATCCTTCAGGTTCT
    GCCCTAGCTCCGCTTCTTGAGAAAAACAAGGCCTTGGTTGAAAAAGTAGATTTGAGTCCA
    GAAGAGCTTGCAACAGCGAAACAGAGTCTAAAAGATCTGGTTGCTTTATTGAAAGAAGAC
    AAGCCAGCAGTCTTTTCTGATAGTAAAACAGGTGTTGAAGTACACTTCTCAAATAAAGAG
    AAGACTGTCATCAAGGGTTTGAAAGTAGAGCGTGTTCAAGCAAGTGCTGAAGAGAAGAAA
    TACTTTGCTGGAGAAGATGCTCATGTCTTTGAAATAGAAGGTTTGGATGAAAAAGGTCAA
    GATGTTGATCTCTCTTACGCTTCTATTGTGAAAATCCCAATTGAAAAAGATAAGAAAGTT
    AAGAAAGTATTTTTCTTACCTGAAGGCAAAGAGGCAGTAGAATTGGCTTTTGAACAAACG
    GATAGTCATGTTATCTTTACAGCACCACACTTTACTCATTATGCCTTTGTTTATGAATCT
    GCTGAAAAACCACAACCTGCTAAACCAGCACCACAAAACAAAGTCCTTCCAAAACCTACT
    TATCAACCGGCTTCTGATCAACAAAAGGCTCCTAAATTGGAAGTTCAAGAGGAAAAGGTT
    GCCTTTCATCGTCAAGAGCATGAAAATACTGAGATGCTAGTTGGGGAACAACGAGTCATC
    ATACAGGGACGAGATGGACTGTTAAGACATGTCTTTGAAGTTGATGAAAACGGTCAGCGT
    CGTCTTCGTTCAACAGAAGTCATCCAAGAAGCGATTCCAGAAATTGTTGAAATTGGAACA
    AAAGTAAAAACAGTACCAGCAGTAGTAGCTACACAGGAAAAACCAGCTCAAAATACAGCA
    GTTAAATCAGAAGAAGCAAGCAAACAATTGCCAAATACAGGAACAGCTGATGCTAATGAA
    GCCCTAATAGCAGGCTTAGCCAGCCTTGGTCTTGCTAGTTTAGCCTTGACCTTGAGACGG
    AAAAGAGAAGATAAAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
    4560
    4620
    4680
    4740
    4800
    4860
    4920
    4941

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPT_RS02670 [old locus tag: SPT_0535 ]
  • symbol: SPT_RS02670
  • description: bacterial Ig-like domain-containing protein
  • length: 1646
  • theoretical pI: 5.02779
  • theoretical MW: 182039
  • GRAVY: -0.630073

⊟Function[edit | edit source]

  • TIGRFAM:
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 48.9)
    and 2 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 23.9)
    conserved hypothetical protein (TIGR01741; HMM-score: 9.9)
  • TheSEED: see SPT_0535
  • PFAM:
    Glyco_hydro_tim (CL0058) Glyco_hydro_85; Glycosyl hydrolase family 85 (PF03644; HMM-score: 245.6)
    and 8 more
    E-set (CL0159) Big_3; Bacterial Ig-like domain (group 3) (PF07523; HMM-score: 122.7)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 45)
    no clan defined YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 41.3)
    B_GA (CL0598) FIVAR; FIVAR domain (PF07554; HMM-score: 26)
    GBD (CL0202) F5_F8_type_C; F5/8 type C domain (PF00754; HMM-score: 24.7)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 23.5)
    PepSY (CL0320) PepSY_2; Peptidase propeptide and YPEB domain (PF13670; HMM-score: 11.5)
    no clan defined Spectrin; Spectrin repeat (PF00435; HMM-score: 8.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.988399
    • TAT(Tat/SPI): 0.009607
    • LIPO(Sec/SPII): 0.001087
    • Cleavage Site: CS pos: 37-38. ALA-EE. Pr: 0.9835
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000795202 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPENSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPT_RS02670&oldid=163212"