From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 20-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN034156
  • locus tag: SPN034156_RS08450 [old locus tag: SPN034156_15190 ]
  • pan locus tag?: PNEUPAN001382000
  • symbol: SPN034156_RS08450
  • pan gene symbol?: endoD
  • synonym:
  • product: bacterial Ig-like domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN034156_RS08450 [old locus tag: SPN034156_15190 ]
  • symbol: SPN034156_RS08450
  • product: bacterial Ig-like domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1566786..1571696
  • length: 4911
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_021006 (1566786..1571696) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0444 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    ATGAAGAATCCATTTTTTGAAAGACGTTGTCGTTACAGTATTCGTAAGTTATCAGTAGGA
    GCCTGCTCGCTGATGATTGGTGCTGTTTTATTTGCTGGTCCAGCCTTGGCTGAAGAAACT
    GCAGTTCCTGAAAATAGCGGAGCTAATACAGAGCTTGTTTCAGGAGAGAGTGAGCATTCG
    ACCAATGAAGCTGATAAGCAGAATGAAGGGGAACATGCTAGAGAAAACAAGCTAGAAAAG
    GCAGAAGCAGCTAGCGCAGCTAAACCAGAGGAAAAAGCAGGTGAGGTGGTTGCAGAAACA
    CCATCTGCAGAAGCAAAACCTAAGTCTGACAAGGAAACAGAAGCAAAGCCCGAAGCAACT
    AACCAAGGGGATGAGTCTAAGCCAGCAGCAGAAGCTAATAAGACTGAAAAAGAAGTCCAG
    CCAGATGTCCCTAAAAATACAGAAAAAACATTAAAACCAAAGGAAATCAAATTTAATTCT
    TGGGAAGAATTGTTAAAATGGGAACCAGGTGCTCGTGAAGATGATGCTATTAACCGCGGA
    TCTGTTGTCCTCGCTTCACGTCGGACAGGTCATTTAGTCAATGAAAAAGCTAGCAAGGAA
    GCAAAAGTTCAAGCCTTATCAAACACCAATTCTAAAGCAAAAGACCATGCTTCTGTTGGT
    GGAGAAGAGTTCAAGGCCTATGCTTTTGACTATTGGCAATATCTAGATTCAATGGTCTTC
    TGGGAAGGTCTCGTACCAACTCCTGACGTTATTGATGCAGGTCACCGTAACGGGGTTCCT
    GTATACGGTACACTCTTCTTCAACTGGTCTAATAGTATTGCAGATCAAGAAAGATTTGCT
    GAAGCTTTGAAGCAAGACGCAGATGGTAGCTTCCCAATTGCCCGTAAATTGGTAGACATG
    GCCAAGTATTATGGCTATGATGGCTATTTCATCAACCAAGAAACAACTGGAGATTTGGTT
    AAACCTCTTGGAGAAAAGATGCGCCAGTTTATGCTCTATAGCAAGGAATATGCTGCTAAG
    GTAAACCATCCAATCAAGTATTCTTGGTATGATGCCATGACCTATAACTATGGACGTTAC
    CATCAAGATGGTTTGGGAGAATACAACTACCAATTCATGCAACCAGAAGGAGATAAGGTT
    CCGGCAGATAACTTCTTTGCTAACTTTAACTGGGATAAGGCTAAAAATGATTACACTATT
    GCAACTGCCAACTGGATTGGTCGTAATCCTTATGATGTATTTGCAGGTTTGGAATTGCAA
    CAGGGTGGTTCCTACAAGACAAAGGTTAAGTGGAATGACATTTTAGACGAAAATGGGAAA
    TTGCGCCTTTCTCTTGGTTTATTTGCCCCAGATACCATTACAAGTTTAGGAAAAACTGGT
    GAAGATTATCATAAAAATGAAGATATCTTCTTTACAGGTTATCAAGGAGACCCCACTGGC
    CAAAAACCAGGTGACAAAGATTGGTATGGTATTGCTAACCTAGTTGCGGACCGTACGCCA
    GCGGTAGGTAATACTTTTACTACTTCTTTTAATACAGGTCATGGTAAAAAATGGTTCGTA
    GATGGTAAGGTTTCTAAGGATTCTGAGTGGAATTATCGTTCAGTATCAGGTGTTCTTCCA
    ACATGGCGCTGGTGGCAGACTTCAACAGGGGAAAAACTTCGTGCAGAATATGATTTTACA
    GATGCCTATAATGGCGGAAATTCCCTTAAATTCTCTGGTGATGTAGCTGGTAAGACAGAT
    CAGGATGTGAGACTTTATTCTACTAAGTTAGAAGTAACTGAGAAGACCAAACTTCGTGTT
    GCCCACAAGGGAGGAAAAGGTTCTAAAGTTTATATGGCATTCTCTACAACTCCAGACTAC
    AAATTCGATGATGCAGATGCATGGAAAGAGCTAACCCTTTCTGACAACTGGACAAATGAA
    GAATTTGATCTCAGCTCACTAGCGGGTAAAACCATCTATGCAGTCAAACTATTTTTCGAG
    CATGAAGGTGCTGTAAAAGATTATCAGTTCAACCTCGGACAATTAACTATCTCGGACAAT
    CACCAAGAGCCACAATCGCCGACAAGCTTTTCTGTAGTGAAACAATCTCTTAAAAATGCC
    CAAGAAGCGGAAGCAGTTGTGCAATTTAAAGGCAACAAGGATGCAGATTTCTATGAAGTT
    TATGAAAAAGATGGAGACAGCTGGAAATTACTAACTGGCTCATCTTCTACAACTATTTAT
    CTACCAAAAGTTAGCCGCTCAGCAAGTGCTCAGGGTACAACTCAAGAACTGAAGGTTGTA
    GCAGTCGGTAAAAATGGAGTTCGTTCAGAAGCTGCAACCACAACCTTTGATTGGGGTATG
    ACTGTAAAAGATACCAGCCTACCAAAACCACTAGCTGAAAATATCGTTCCAGGTGCAACA
    GTTATTGATAGTACTTTCCCTAAGACTGAAGGTGGAGAAGGTATTGAAGGTATGTTGAAC
    GGTACCATTACTAGCTTGTCAGATAAATGGTCTTCAGCTCAGTTGAGTGGTAGTGTGGAT
    ATTCGTTTGACCAAGCCACGTACCGTTGTTAGATGGGTCATGGATCATGCAGGGGCTGGT
    GGTGAGTCTGTTAACGATGGCTTGATGAACACCAAAGACTTTGACCTTTATTATAAAGAT
    GCAGATGGTGAGTGGAAGCTAGCTAAGGAAGTCCGTGGTAACAAAGCACACGTGACAGAT
    ATCACTCTTGATAAACCAATCACTGCTCAAGACTGGCGCTTGAATGTTGTCACTTCTGAC
    AATGGAACTCCATGGAAGGCTATTCGTATCTATAACTGGAAAATGTATGAAAAGCTTGAT
    ACTGAGAGTGTCAATATTCCGATGGCCAAGGCTGCAGCCCGTTCTCTAGGCAATAACAAG
    GTACAAGTTGGCTTTGCAGATGTACCGGCTGGAGCAACTATTACCGTTTATGATAATCCA
    AATTCTCAAACTCCGCTTGCAACCTTGAAGAGCGAAGTTGGAGGAGACCTAGCAAGTGCA
    CCATTGGATTTGACAAATCAATCTGGTCTTCTTTATTATCGTACCCAGTTGCCAGGCAAG
    GAAATTAGTAATGTCCTAGCAGTTTCCGTTCCAAAAGATGACAGAAGAATCAAGTCAGTC
    AGCCTAGAAACAGGACCTAAGAAAACAAGCTACGCCGAAGGGGAGGATTTGGACCTTAGA
    GGTGGTGTTCTTCGAGTTCAGTATGAAGGAGGAACTGAGGACGAACTCATTCGCCTAACT
    CACGCAGGTGTATCAGTATCAGGTTTTGATACGCATCATAAGGGAGAACAGAATCTTACT
    CTCCAATATTTGGGACAACCGGTAAATGCTAATTTGTCAGTGACTGTCACTGGCCAAGAC
    GAAGCAAGTCCGAAAACTATTTTGGGAATTGAAGTAAGTCAGGAACCGAAAAAAGATTAC
    CTAGTTGGTGATAGCTTAGACTTGTCTGAAGGACGCTTTGCAGTGGCTTATAGCAATGAC
    ACCATGGAAGAACATTCCTTTACTGATGAGGGAGTTGAAATTTCTGGTTACGATGCTCAA
    AAGACTGGTCGTCAAACCTTGACGCTTCATTACCAAGGCCATGAAGTTAGCTTTGATGTT
    TTGGTATCTCCAAAAGCAGCATTGAACGATGAGTACCTCAAACAAAAATTAGCAGAAGTT
    GAAGCTGCTAAGAACAAGGTGGTCTATAACTTTGCTTCATCAGAAGTAAAAGAAGCCTTC
    TTGAAAGCAATTGAAGCGGCCGAACAAGTGTTGAAAGACCATGAAACTAGCACCCAAGAT
    CAAGTCAATGACCGACTTAATAAATTGACAGAAGCTCATAAAGCTCTGAATGGTCAAGAG
    AAATTTAAGGAAGAAAAGACAGAGCTTGATCGTTTAACAGGTGAGGTTCAAGAACTCTTG
    GCTGCCAAACCAAACCATCCTTCAGGTTCTGCCCTAGCTCCGCTTCTTGAGAAAAACAAG
    GCCTTGGTTGAAAAAGTAGATTTGAGTCCAGAAGAGCTTGCAACAGCGAAACAGAGTCTA
    AAAGATCTGGTTGCTTTATTGAAAGAAGACAAGCCAGCAGTCTTTTCTGATAGTAAAACA
    GGTGTTGAAGTACACTTCTCAAATAAAGAGAAGACTGTCATCAAGGGTTTGAAAGTAGAG
    CGTGTTCAAGCAAGTGCTGAAGAGAAGAAATACTTTGCTGGAGAAGATGCTCATGTCTTT
    GAAATAGAAGGTTTGGATGAAAAAGGTCAAGATGTTGATCTCTCTTATGCTTCTATTGTG
    AAAATCCCAATTGAAAAAGATAAGAAAGTTAAGAAAGTATTTTTCTTACCTGAAGGCAAA
    GAGGCAGTAGAATTGGCTTTTGAACAAACGGATAGTCATGTTATCTTTACAGCACCTCAC
    TTTACTCATTATGCCTTTGTTTATGAATCTGCTGAAAAACCACAACCTGCTAAACCAGCA
    CCACAAAACACAGTCCTTCCAAAACCTACTTATCAACCGGCTTCTGATCAACAAAAGGCT
    CCTAAATTGGAAGTTCAAGAGGAAAAGGTTGCCTTTCATCGTCAAGAGCATGAAAATGCT
    GAGATGCTAGTTGGGGAACAACGAGTCATCATACAGGGACGAGATGGACTGTTAAGACAT
    GTCTTTGAAGTTGATGAAAACGGTCAGCGTCGTCTTCGTTCAACAGAAGTCATCCAAGAA
    GCGATTCCAGAAATTGTTGAAATTGGAACAAAAGTAAAAACAGTACTAGCAGTAGTAGCT
    ACACAGGAAAAACCAGCTCAAAATACAGCAGTTAAATCAGAAGAAGCAAGCAAACAATTG
    CCAAATACAGGAACAGCTGATGCTAATGAAGCCCTAATAGCAGGCTTAGCCAGCCTTGGT
    CTTGCTAGTTTAGCCTTGACCTTGAGACGGAAAAGAGAAGATAAAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
    4560
    4620
    4680
    4740
    4800
    4860
    4911

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN034156_RS08450 [old locus tag: SPN034156_15190 ]
  • symbol: SPN034156_RS08450
  • description: bacterial Ig-like domain-containing protein
  • length: 1636
  • theoretical pI: 5.04316
  • theoretical MW: 180964
  • GRAVY: -0.622433

⊟Function[edit | edit source]

  • TIGRFAM:
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 48.9)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 23.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Glyco_hydro_tim (CL0058) Glyco_hydro_85; Glycosyl hydrolase family 85 (PF03644; HMM-score: 245.6)
    and 7 more
    E-set (CL0159) Big_3; Bacterial Ig-like domain (group 3) (PF07523; HMM-score: 122.8)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 46.8)
    no clan defined YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 41.3)
    GBD (CL0202) F5_F8_type_C; F5/8 type C domain (PF00754; HMM-score: 24.7)
    B_GA (CL0598) FIVAR; FIVAR domain (PF07554; HMM-score: 24.4)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 23.4)
    PepSY (CL0320) PepSY_2; Peptidase propeptide and YPEB domain (PF13670; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.988399
    • TAT(Tat/SPI): 0.009607
    • LIPO(Sec/SPII): 0.001087
    • Cleavage Site: CS pos: 37-38. ALA-EE. Pr: 0.9835
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000795163 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPENSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVLAVVATQEKPAQNTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPN034156_RS08450&oldid=139156"