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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_0607 [new locus tag: SPH_RS02940 ]
  • pan locus tag?: PNEUPAN001382000
  • symbol: SPH_0607
  • pan gene symbol?: endoD
  • synonym:
  • product: endo-beta-N-acetylglucosaminidase D

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_0607 [new locus tag: SPH_RS02940 ]
  • symbol: SPH_0607
  • product: endo-beta-N-acetylglucosaminidase D
  • replicon: chromosome
  • strand: +
  • coordinates: 555893..560806
  • length: 4914
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    ATGAAGAATCCATTTTTTGAAAGACGTTGTCGTTACAGTATTCGTAAGTTATCAGTAGGA
    GCCTGCTCGCTGATGATTGGTGCTGTTTTATTTGCTGGTCCAGCCTTGGCTGAAGAAACT
    GCAGTTCCTGAAAATAGCGGAGCTAATACAGAGCTTGTTTCAGGAGAGAGTGAGCATTCG
    ACCAATGAAGCTGATAAGCAGAATGAAGGGGAACATGCTAGAGAAAACAAGCTAGAAAAG
    GCAGAAGGAGTAGCGACAGCATCTGAAACTGCTTCGCCAGCAAGCAATGAAGCTGCAACT
    ACTGAAACTGCAGAAGCAAAACCTAAGTCTGACAAGGAAACAGAAGCAAAGCCCGAAGCA
    ACTAACCAAGGGGATGAGTCTAAGCCAGCAGCCGAAGCTAATAAGACTGAAAAAGAAGTC
    CAGCCAGATGTCCCTAAAAATACAGAAAAAACATTAAAACCAAAGGAAATCAAATTTAAT
    TCTTGGGAAGAATTGTTAAAATGGGAACCAGGTGCTCGTGAAGATGATGCTATTAACCGC
    GGATCTGTTGTCCTCGCTTCACGTCGGACAGGTCATTTAGTCAATGAAAAAGCTAGCAAG
    GAAGCAAAAGTTCAAGCCTTATCAAACACCAATTCTAAAGCAAAAGACCATGCTTCTGTT
    GGTGGAGAAGAGTTCAAGGCCTATGCTTTTGACTATTGGCAATATCTAGATTCAATGGTC
    TTCTGGGAAGGTCTCGTACCAACTCCTGACGTTATTGATGCAGGTCACCGTAACGGGGTT
    CCTGTATACGGTACACTCTTCTTCAACTGGTCTAATAGTATTGCAGATCAAGAAAGATTT
    GCTGAAGCTTTGAAGCAAGACGCAGATGGTAGCTTCCCAATTGCCCGTAAATTGGTAGAC
    ATGGCCAAGTATTATGGCTATGATGGCTATTTCATCAACCAAGAAACAACTGGAGATTTG
    GTTAAACCTCTTGGAGAAAAGATGCGCCAGTTTATGCTCTATAGCAAGGAATATGCTGCT
    AAGGTAAACCATCCAATCAAGTATTCTTGGTACGATGCCATGACCTATAACTATGGACGT
    TATCATCAAGATGGTTTGGGAGAATACAACTACCAATTCATGCAACCAGAAGGAGATAAG
    GTTCCGGCAGATAACTTCTTTGCTAACTTTAACTGGGATAAGACTAAAAATGATTACACT
    ATTGCAACTGCCAACTGGATTGGACGTAATCCTTATGATGTATTTGCAGGTTTGGAATTG
    CAACAGGGTGGTTCCTACAAGACAAAGGTTAAGTGGAATGACATTTTAGACGAAAATGGG
    AAATTGCGCCTTTCTCTTGGTTTATTTGCCCCAGATACCATTACAAGTTTAGGAAAAACT
    GGTGAAGATTATCATAAAAATGAAGATATCTTCTTTACAGGTTATCAAGGAGACCCTACT
    GGCCAAAAACCAGGTGACAAAGATTGGTATGGTATTGCTAACCTAGTTGCGGACCGTACG
    CCAGCGGTAGGTAATACTTTTACTACTTCTTTTAATACAGGTCATGGTAAAAAATGGTTC
    GTAGATGGTAAGGTTTCTAAGGATTCTGAGTGGAATTATCGTTCAGTATCAGGTGTTCTT
    CCAACATGGCGCTGGTGGCAGACTTCAACAGGGGAAAAACTTCGTGCAGAATATGATTTT
    ACAGATGCCTATAATGGCGGAAATTCCCTTAAATTCTCTGGTGATGTAGCCGGTAAGACA
    GATCAGGATGTGAGACTTTATTCTACTAAGTTAGAAGTAACTGAGAAGACCAAACTTCGT
    GTTGCCCACAAGGGAGGAAAAGGTTCTAAAGTTTATATGGCATTCTCTACAACTCCAGAC
    TACAAATTCGATGATGCAGATGCATGGAAAGAGCTAACCCTTTCTGACAACTGGACAAAT
    GAAGAATTTGATCTTAGCTCACTAGCGGGTAAAACCATCTATGCAGTCAAACTATTTTTC
    GAGCATGAAGGTGCTGTAAAAGATTATCAGTTCAACCTAGGACAATTAACTATCTCGGAC
    AATCACCAAGAGCCACAATCGCCGACAAGCTTTTCTGTAGTGAAACAATCGCTTAAAAAT
    GCCCAAGAAGCGGAAGCAGTTGTGCAATTTAAAGGCAACAAGGATGCAGATTTCTATGAA
    GTTTATGAAAAAGATGGAGACAGCTGGAAATTACTAACTGGCTCATCTTCTACAACTATT
    TATCTACCAAAAGTTAGCCGCTCAGCAAGTGCTCAGGGTACAACTCAAGAACTGAAGGTT
    GTAGCAGTCGGTAAAAATGGAGTTCGTTCAGAAGCTGCAACCACAACCTTTGATTGGGGT
    ATGACTGTAAAAGATACCAGCCTACCAAAACCACTAGCTGAAAATATCGTTCCAGGTGCA
    ACAGTTATTGATAGTACTTTCCCTAAGACTGAAGGTGGAGAAGGTATTGAAGGTATGTTG
    AACGGTACCATTACTAGCTTGTCAGATAAATGGTCTTCAGCTCAGTTGAGTGGTAGTGTG
    GATATTCGTTTGACCAAGCCACGTACCGTTGTTAGATGGGTCATGGATCATGCAGGGGCT
    GGTGGTGAGTCTGTTAACGATGGCTTGATGAACACTAAAGACTTTGACCTTTATTATAAA
    GATGCAGATGGTGAGTGGAAGCTAGCTAAGGAAGTCCGTGGTAACAAAGCACACGTGACA
    GATATCACTCTTGATAAACCAATCACTGCTCAAGACTGGCGCTTGAATGTTGTCACTTCT
    GACAATGGAACTCCATGGAAGGCTATTCGTATCTATAACTGGAAAATGTATGAAAAGCTT
    GATACTGAGAGTGTCAATATTCCGATGGCCAAGGCTGCAGCCCGTTCTCTAGGCAATAAC
    AAGGTACAAGTTGGCTTTGCAGATGTACCGGCTGGAGCAACTATTACCGTTTATGATAAT
    CCAAATTCTCAAACTCCGCTCGCAACCTTGAAGATCGAAGTTGGAGGAGACCTAGCAAGT
    GCACCATTGGATTTGACAAATCAATCTGGTCTTCTTTATTATCGTACCCAGTTGCCAGGC
    AAGGAAATTAGTAATGTCCTAGCAGTTTCCGTTCCAAAAGATGACAGAAGAATCAAGTCA
    GTCAGCCTAGAAACAGGACCTAAGAAAACAAGCTACGCCGAAGGGGAGGATTTGGACCTT
    AGAGGTGGTGTTCTTCGAGTTCAGTATGAAGGAGGAACTGAGGACGAACTCATTCGCCTA
    ACTCACGCAGGTGTATCAGTATCAGGTTTTGATACGCATCATAAGGGAGAACAGAATCTT
    ACTCTCCAATATTTGGGACAACCAGTAAATGCTAATTTGTCAGTGACTGTCACTGGCCAA
    GATGAAGCAAGTCCGAAAACTATTTTGGGAATTGAAGTAAGTCAGGAACCGAAAAAAGAT
    TACCTAGTTGGTGATAGCTTAGACTTGTCTGAAGGACGCTTTGCAGTGGCTTATAGCAAT
    GACACCATGGAAGAACATTCCTTTACTGATGAGGGAGTTGAAATTTCTGGTTACGATGCT
    CAAAAGACTGGTCGTCAAACCTTGACGCTTCATTACCAAGGCCATGAAGTTAGCTTTGAT
    GTTTTGGTATCTCCAAAAGCAGCATTGAACGATGAGTACCTCAAACAAAAATTAGCAGAA
    GTTGAAGCTGCTAAGAACAAGGTGGTCTATAACTTTGCTTCATCAGAAGTAAAAGAAGCC
    TTCTTGAAAGCAATTGAAGCGGCCGAACAAGTGTTGAAAGACCATGAAACTAGCACCCAA
    GATCAAGTCAATGACCGACTTAATAAATTGACAGAAGCTCATAAAGCTCTGAATGGTCAA
    GAGAAATTTAAGGAAGAAAAGACAGAGCTTGATCGCTTAACAGGTGAGGTTCAAGAACTC
    TTGGCTGCCAAACCAAACCATCCTTCAGGTTCTGCCCTAGCTCCGCTTCTTGAGAAAAAC
    AAGGCCTTGGTTGAAAAAGTAGATTTGAGTCCAGAAGAGCTTGCAACAGCGAAACAGAGT
    CTAAAAGATCTGGTTGCTTTATTGAAAGAAGACAAGCCAGCAGTCTTTTCTGATAGTAAA
    ACAGGTGTTGAAGTACACTTCTCAAATAAAGAGAAGACTGTCATCAAGGGTTTGAAAGTA
    GAGCGTGTTCAAGCAAGTGCTGAAGAGAAGAAATACTTTGCTGGAGAAGATGCTCATGTC
    TTTGAAATAGAAGGTTTGGATGAAAAAGGTCAAGATGTTGATCTCTCTTACGCTTCTATT
    GTGAAAATCCCAATTGAAAAAGATAAGAAAGTTAAGAAAGTATTTTTCTTACCTGAAGGC
    AAAGAGGCAGTAGAATTGGCTTTTGAACAAACGGATAGTCATGTTATCTTTACAGCACCA
    CACTTTACTCATTATGCCTTTGTTTATGAATCTGCTGAAAAACCACAACCTGCTAAACCA
    GCACCACAAAACAAAGTCCTTCCAAAACCTACTTATCAACCGGCTTCTGATCAACAAAAG
    GCTCCTAAATTGGAAGTTCAAGAGGAAAAGGTTGCCTTTCATCGTCAAGAGCATGAAAAT
    GCTGAGATGCTAGTTGGGGAACAACGAGTCATCATACAGGGACGAGATGGACTGTTAAGA
    CATGTCTTTGAAGTTGATGAAAACGGTCAGCGTCGTCTTCGTTCAACAGAAGTCATCCAA
    GAAGCGATTCCAGAAATTGTTGAAATTGGAACAAAAGTAAAAACAGTACCAGCAGTAGTA
    GCTACACAGGAAAAACCAGCTCAAAATACAGCAGTTAAATCAGAAGAAGCAAGCAAACAA
    TTGCCAAATACAGGAACAGCTGATGCTAATGAAGCCCTAATAGCAGGCTTAGCCAGCCTC
    GGTCTTGCTAGTTTAGCCTTGACCTTGAGACGGAAAAGAGAAGATAAAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
    4560
    4620
    4680
    4740
    4800
    4860
    4914

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_0607 [new locus tag: SPH_RS02940 ]
  • symbol: SPH_0607
  • description: endo-beta-N-acetylglucosaminidase D
  • length: 1637
  • theoretical pI: 5.04108
  • theoretical MW: 181056
  • GRAVY: -0.624618

⊟Function[edit | edit source]

  • TIGRFAM:
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 48.9)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 23.9)
  • TheSEED  :
    • Endo-beta-N-acetylglucosaminidase (EC 3.2.1.96)
  • PFAM:
    Glyco_hydro_tim (CL0058) Glyco_hydro_85; Glycosyl hydrolase family 85 (PF03644; HMM-score: 245.5)
    and 7 more
    E-set (CL0159) Big_3; Bacterial Ig-like domain (group 3) (PF07523; HMM-score: 122.8)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 46.9)
    no clan defined YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 41.3)
    GBD (CL0202) F5_F8_type_C; F5/8 type C domain (PF00754; HMM-score: 24.7)
    B_GA (CL0598) FIVAR; FIVAR domain (PF07554; HMM-score: 24.4)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 23.5)
    PepSY (CL0320) PepSY_2; Peptidase propeptide and YPEB domain (PF13670; HMM-score: 11.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.988399
    • TAT(Tat/SPI): 0.009607
    • LIPO(Sec/SPII): 0.001087
    • Cleavage Site: CS pos: 37-38. ALA-EE. Pr: 0.9835
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPENSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVATASETASPASNEAATTETAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWDKTKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKIEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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