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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_0498 [new locus tag: SP_RS02450 ]
  • pan locus tag?: PNEUPAN001382000
  • symbol: SP_0498
  • pan gene symbol?: endoD
  • synonym:
  • product: putative endo-beta-N-acetylglucosaminidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_0498 [new locus tag: SP_RS02450 ]
  • symbol: SP_0498
  • product: putative endo-beta-N-acetylglucosaminidase
  • replicon: chromosome
  • strand: +
  • coordinates: 476529..481508
  • length: 4980
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    ATGAAGAATCCATTTTTTGAAAGACGTTGTCGTTACAGTATTCGTAAGTTATCAGTAGGA
    GCCTGCTCGCTGATGATTGGTGCTGTTTTATTTGCTGGTCCAGCCTTGGCTGAAGAAACT
    GCAGTTCCTGAAAATAGCGGAGCTAATACAGAGCTTGTTTCAGGAGAGAGTGAGCATTCG
    ACCAATGAAGCTGATAAGCAGAATGAAGGGGAACATGCTAGAGAAAACAAGCTAGAAAAG
    GCAGAAGGAGTAGCGATAGCATCTGAAACTGCTTCGCCAGCAAGCAATGAAGCTGCAACT
    ACTGAAACTGCAGAAGCAGCTAGCGCAGCTAAACCAGAGGAAAAAGCAAGTGAGGTGGTT
    GCAGAAACACCATCTGCAGAAGCAAAACCTAAGTCTGACAAGGAAACAGAAGCAAAGCCC
    GAAGCAACTAACCAAGGGGATGAGTCTAAACCAGCAGCAGAAGCTAATAAGACTGAAAAA
    GAAGTCCAGCCAGATGTCCCTAAAAATACAGAAAAAACATTAAAACCAAAGGAAATCAAA
    TTTAATTCTTGGGAAGAATTGTTAAAATGGGAACCAGGTGCTCGTGAAGATGATGCTATT
    AACCGCGGATCTGTTGTCCTCGCTTCACGTCGGACAGGTCATTTAGTCAATGAAAAAGCT
    AGCAAGGAAGCAAAAGTTCAAGCCTTATCAAACACCAATTCTAAAGCAAAAGACCATGCT
    TCTGTTGGTGGAGAAGAGTTCAAGGCCTATGCTTTTGACTATTGGCAATATCTAGATTCA
    ATGGTCTTCTGGGAAGGTCTCGTACCAACTCCTGACGTTATTGATGCAGGTCACCGTAAC
    GGGGTTCCTGTATACGGTACACTCTTCTTCAACTGGTCTAATAGTATTGCAGATCAAGAA
    AGATTTGCTGAAGCTTTGAAGCAAGACGCAGATGGTAGCTTCCCAATTGCCCGTAAATTG
    GTAGACATGGCCAAGTATTATGGCTATGATGGCTATTTCATCAACCAAGAAACAACTGGA
    GATTTGGTTAAACCTCTTGGAGAAAAGATGCGCCAGTTTATGCTCTATAGCAAGGAATAT
    GCTGCTAAGGTAAACCATCCAATCAAGTATTCTTGGTACGATGCCATGACCTATAACTAT
    GGACGTTATCATCAAGATGGTTTGGGAGAATACAACTACCAATTCATGCAACCAGAAGGA
    GATAAGGTTCCGGCAGATAACTTCTTTGCTAACTTTAACTGGGATAAGGCTAAAAATGAT
    TACACTATTGCAACTGCCAACTGGATTGGTCGTAATCCTTATGATGTATTTGCAGGTTTG
    GAATTGCAACAGGGTGGTTCCTACAAGACAAAGGTTAAGTGGAATGACATTTTAGACGAA
    AATGGGAAATTGCGCCTTTCTCTTGGTTTATTTGCCCCAGATACCATTACAAGTTTAGGA
    AAAACTGGTGAAGATTATCATAAAAATGAAGATATCTTCTTTACAGGTTATCAAGGAGAC
    CCTACTGGCCAAAAACCAGGTGACAAAGATTGGTATGGTATTGCTAACCTAGTTGCGGAC
    CGTACGCCAGCGGTAGGTAATACTTTTACTACTTCTTTTAATACAGGTCATGGTAAAAAA
    TGGTTCGTAGATGGTAAGGTTTCTAAGGATTCTGAGTGGAATTATCGTTCAGTATCAGGT
    GTTCTTCCAACATGGCGCTGGTGGCAGACTTCAACAGGGGAAAAACTTCGTGCAGAATAT
    GATTTTACAGATGCCTATAATGGCGGAAATTCCCTTAAATTCTCTGGTGATGTAGCCGGT
    AAGACAGATCAGGATGTGAGACTTTATTCTACTAAGTTAGAAGTAACTGAGAAGACCAAA
    CTTCGTGTTGCCCACAAGGGAGGAAAAGGTTCTAAAGTTTATATGGCATTCTCTACAACT
    CCAGACTACAAATTCGATGATGCAGATGCATGGAAAGAGCTAACCCTTTCTGACAACTGG
    ACAAATGAAGAATTTGATCTTAGCTCACTAGCGGGTAAAACCATCTATGCAGTCAAACTA
    TTTTTCGAGCATGAAGGTGCTGTAAAAGATTATCAGTTTAACCTAGGACAATTAACTATC
    TCGGACAATCACCAAGAGCCACAATCGCCGACAAGCTTTTCTGTAGTGAAACAATCTCTT
    AAAAATGCCCAAGAAGCGGAAGCAGTTGTGCAATTTAAAGGCAACAAGGATGCAGATTTC
    TATGAAGTTTATGAAAAAGATGGAGACAGCTGGAAATTACTAACTGGCTCATCTTCTACA
    ACTATTTATCTACCAAAAGTTAGCCGCTCAGCAAGTGCTCAGGGTACAACTCAAGAACTG
    AAGGTTGTAGCAGTCGGTAAAAATGGAGTTCGTTCAGAAGCTGCAACCACAACCTTTGAT
    TGGGGTATGACTGTAAAAGATACCAGCCTACCAAAACCACTAGCTGAAAATATCGTTCCA
    GGTGCAACAGTTATTGATAGTACTTTCCCTAAGACTGAAGGTGGAGAAGGTATTGAAGGT
    ATGTTGAACGGTACCATTACTAGCTTGTCAGATAAATGGTCTTCAGCTCAGTTGAGTGGT
    AGTGTGGATATTCGTTTGACCAAGCCACGTACCGTTGTTAGATGGGTCATGGATCATGCA
    GGAGCTGGTGGTGAGTCTGTTAACGATGGCTTGATGAACACTAAAGACTTTGACCTTTAT
    TATAAAGATGCAGATGGTGAGTGGAAGCTAGCTAAGGAAGTCCGTGGTAACAAAGCACAC
    GTGACAGATATCACTCTTGATAAACCAATCACTGCTCAAGACTGGCGCTTGAATGTTGTC
    ACTTCTGACAATGGAACTCCATGGAAGGCTATTCGTATCTATAACTGGAAAATGTATGAA
    AAGCTTGATACTGAGAGTGTCAATATTCCGATGGCCAAGGCTGCAGCCCGTTCTCTAGGC
    AATAACAAGGTACAAGTTGGCTTTGCAGATGTACCGGCTGGAGCAACTATTACCGTTTAT
    GATAATCCAAATTCTCAAACTCCGCTCGCAACCTTGAAGAGCGAAGTTGGAGGAGACCTA
    GCAAGTGCACCATTGGATTTGACAAATCAATCTGGTCTTCTTTATTATCGTACCCAGTTG
    CCAGGCAAGGAAATTAGTAATGTCCTAGCAGTTTCCGTTCCAAAAGATGACAGAAGAATC
    AAGTCAGTCAGCCTAGAAACAGGACCTAAGAAAACAAGCTACGCCGAAGGGGAGGATTTG
    GACCTTAGAGGTGGTGTTCTTCGAGTTCAGTATGAAGGAGGAACTGAGGACGAACTCATT
    CGCCTAACTCACGCAGGTGTATCAGTATCAGGTTTTGATACGCATCATAAGGGAGAACAG
    AATCTTACTCTCCAATATTTGGGACAACCGGTAAATGCTAATTTGTCAGTGACTGTCACT
    GGCCAAGACGAAGCAAGTCCGAAAACTATTTTGGGAATTGAAGTAAGTCAGGAACCGAAA
    AAAGATTACCTAGTTGGTGATAGCTTAGACTTGTCTGAAGGACGCTTTGCAGTGGCTTAT
    AGCAATGACACCATGGAAGAACATTCCTTTACTGATGAGGGAGTTGAAATTTCTGGTTAC
    GATGCTCAAAAGACTGGTCGTCAAACCTTGACGCTTCATTACCAAGGCCATGAAGTTAGC
    TTTGATGTTTTGGTATCTCCAAAAGCAGCATTGAACGATGAGTACCTCAAACAAAAATTA
    GCAGAAGTTGAAGCTGCTAAGAACAAGGTGGTCTATAACTTTGCTTCATCAGAAGTAAAA
    GAAGCCTTCTTGAAAGCAATTGAAGCGGCCGAACAAGTGTTGAAAGACCATGAAACTAGC
    ACCCAAGATCAAGTCAATGACCGACTTAATAAATTGACAGAAGCTCATAAAGCTCTGAAT
    GGTCAAGAGAAATTTACGGAAGAAAAGACAGAGCTTGATCGCTTAACAGGTGAGGTTCAA
    GAACTCTTGGCTGCCAAACCAAACCATCCTTCAGGTTCTGCCCTAGCTCCGCTTCTTGAG
    AAAAACAAGGCCTTGGTTGAAAAAGTAGATTTGAGTCCAGAAGAGCTTACAACAGCGAAA
    CAGAGTCTAAAAGATCTGGTTGCTTTATTGAAAGAAGACAAGCCAGCAGTCTTTTCTGAT
    AGTAAAACAGGTGTTGAAGTACACTTCTCAAATAAAGAGAAGACTGTCATCAAGGGTTTG
    AAAGTAGAGCGTGTTCAAGCAAGTGCTGAAGAGAAGAAATACTTTGCTGGAGAAGATGCT
    CATGTCTTTGAAATAGAAGGTTTGGATGAAAAAGGTCAAGATGTTGATCTCTCTTATGCT
    TCTATTGTGAAAATCCCAATTGAAAAAGATAAGAAAGTTAAGAAAGTATTTTTCTTACCT
    GAAGGCAAAGAGGCAGTAGAATTGGCTTTTGAACAAACGGATAGTCATGTTATCTTTACA
    GCACCTCACTTTACTCATTATGCCTTTGTTTATGAATCTGCTGAAAAACCACAACCTGCT
    AAACCAGCACCACAAAACACAGTCCTTCCAAAACCTACTTATCAACCGACTTCTGATCAA
    CAAAAGGCTCCTAAATTGGAAGTTCAAGAGGAAAAGGTTGCCTTTCATCGTCAAGAGCAT
    GAAAATACTGAGATGCTAGTTGGGGAACAACGAGTCATCATACAGGGACGAGATGGACTG
    TTAAGACATGTCTTTGAAGTTGATGAAAACGGTCAGCGTCGTCTTCGTTCAACAGAAGTC
    ATCCAAGAAGCGATTCCAGAAATTGTTGAAATTGGAACAAAAGTAAAAACAGTACCAGCA
    GTAGTAGCTACACAGGAAAAACCAGCTCAAAATACAGCAGTTAAATCAGAAGAAGCAAGC
    AAACAATTGCCAAATACAGGAACAGCTGATGCTAATGAAGCCCTAATAGCAGGCTTAGCC
    AGCCTTGGTCTTGCTAGTTTAGCCTTGACCTTGAGACGGAAAAGAGAAGATAAAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
    4560
    4620
    4680
    4740
    4800
    4860
    4920
    4980

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_0498 [new locus tag: SP_RS02450 ]
  • symbol: SP_0498
  • description: putative endo-beta-N-acetylglucosaminidase
  • length: 1659
  • theoretical pI: 4.95677
  • theoretical MW: 183202
  • GRAVY: -0.621941

⊟Function[edit | edit source]

  • TIGRFAM:
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 48.8)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 23.8)
  • TheSEED  :
    • Endo-beta-N-acetylglucosaminidase (EC 3.2.1.96)
  • PFAM:
    Glyco_hydro_tim (CL0058) Glyco_hydro_85; Glycosyl hydrolase family 85 (PF03644; HMM-score: 245.6)
    and 6 more
    E-set (CL0159) Big_3; Bacterial Ig-like domain (group 3) (PF07523; HMM-score: 122.8)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 44.9)
    no clan defined YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 41.3)
    GBD (CL0202) F5_F8_type_C; F5/8 type C domain (PF00754; HMM-score: 24.7)
    B_GA (CL0598) FIVAR; FIVAR domain (PF07554; HMM-score: 24.4)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 23.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.988399
    • TAT(Tat/SPI): 0.009607
    • LIPO(Sec/SPII): 0.001087
    • Cleavage Site: CS pos: 37-38. ALA-EE. Pr: 0.9835
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPENSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTETAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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