From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_1545 [new locus tag: SP_RS07610 ]
  • pan locus tag?: PNEUPAN002829000
  • symbol: SP_1545
  • pan gene symbol?: ypmB
  • synonym:
  • product: conserved hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_1545 [new locus tag: SP_RS07610 ]
  • symbol: SP_1545
  • product: conserved hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1452696..1453127
  • length: 432
  • essential: yes [1] DEG

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGACGATTTTGTTTGTGGTTATCAGTGGTTCCTTTCTGTATATGGTTTCTCTTAGCATG
    AAACCCTATCAAACAGCTAAAAGTGAAGGAGAAAAATTAGCTCAGCAGTATGCAGGATTA
    GAGCAGGCTGATCAGGTTGATTTATACAATGGCTTGGAATCTTATTACAGCGTTCTTGGT
    CGTAACAAACAGCAAGAAGCGCTTGCTGTCCTGATTGGTAAAGATGACCATAAGATTTAC
    GTTTATCAGCTAAATCAGGGTGTTTCACAAGAAAAAGCAGAAACGGTTTCTAAGGAAAAG
    GGAGCTGGCGAGATTGACAAGATAACCTTTGGCCGTTATCAAGATAAGCCAATCTGGGAA
    GTTAAGTCAGGATCTGATTTTTATCTAGTAGATTTTGAAACAGGAGCATTGGTCAACAAG
    GAGGGCCTATGA
    60
    120
    180
    240
    300
    360
    420
    432

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_1545 [new locus tag: SP_RS07610 ]
  • symbol: SP_1545
  • description: conserved hypothetical protein
  • length: 143
  • theoretical pI: 4.6383
  • theoretical MW: 16022
  • GRAVY: -0.342657

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • FIG01114898: hypothetical protein
  • PFAM:
    Cystatin (CL0121) DUF5590; Domain of unknown function (DUF5590) (PF17881; HMM-score: 48.7)
    and 1 more
    PepSY (CL0320) PepSY; Peptidase propeptide and YPEB domain (PF03413; HMM-score: 14.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.9894
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0103
  • SignalP: Signal peptide SP(Sec/SPI) length 28 aa
    • SP(Sec/SPI): 0.470113
    • TAT(Tat/SPI): 0.009785
    • LIPO(Sec/SPII): 0.088007
    • Cleavage Site: CS pos: 28-29. AKS-EG. Pr: 0.2555
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTILFVVISGSFLYMVSLSMKPYQTAKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQLNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKEGL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site: 1453184 [2]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Jane A Thanassi, Sandra L Hartman-Neumann, Thomas J Dougherty, Brian A Dougherty, Michael J Pucci
    Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae.
    Nucleic Acids Res: 2002, 30(14);3152-62
    [PubMed:12136097] [WorldCat.org] [DOI] (I p)
  2. ↑ 2.0 2.1 2.2 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
    The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
    PLoS Pathog: 2018, 14(12);e1007461
    [PubMed:30517198] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SP_1545&oldid=3766"