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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae A026
  • locus tag: T308_RS01540 [old locus tag: T308_01540 ]
  • pan locus tag?: PNEUPAN001056000
  • symbol: T308_RS01540
  • pan gene symbol?: celR
  • synonym:
  • product: BglG family transcription antiterminator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: T308_RS01540 [old locus tag: T308_01540 ]
  • symbol: T308_RS01540
  • product: BglG family transcription antiterminator
  • replicon: chromosome
  • strand: +
  • coordinates: 277262..279241
  • length: 1980
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_022655 (277262..279241) NCBI
  • BioCyc: T308_RS01540 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0280 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGAATGTGTTAAACATTAAAGAGAAAGATATCCTTCAATTTTTAATAAAAAATAAGGAA
    CGTTTTGTTACAAGCAAAGAACTGGCAGAATATTTATCCTGTTCAGATAGAACTGTCCGT
    AATGTACTGAAATTAATTGAGAAGACAATGATTATTCAAGGAGTCCGGTTGATTTCAAAA
    CAAGGTCAAGGGTATCAAATATTTTTTGAGAATCAAGGCGCTTACCAGGAGTTTAGACAA
    ACTTATGAACTGGAAGAAGACTATACGAAAACTGCGGTTTCAAAAGGTGATGATCGTTTA
    GTATTTATCTTAAATAAATTATTATTTGAGCAAGTTCCAGTTCTTTTTGATGATTTAGCT
    GATGAACTTTACGTTAGTCGTTCAACATTATCTCATGATTTCAGAAAGATACGAGTGATG
    TTATCAGAGTATAATTTGTCCATTGAGAGTAGGGCGAATAAAGGAGTTTATGTCTCAGGC
    GAGGAACGTGATAAACGACGTTTTATCATAAATTATTTCCTAGAGAATCAATTTTTTAAA
    ACAATACATTGCTATGTAAAATTTAACTTTTTTGATCAAACTGTTCCATTAGAAGAATTT
    GCTAGAATTGTTTTGGATGAATGCCAAGAGGCCAACCTAAAACTATCTGATTTTGTACTA
    CAGAATTTAGTAGTTCACATAGCATTGTCTGTGATTCGTTTAAAATCCGGATTTGAAATA
    AAAAATATAGACTGTCAGATGACTGATGATGCAATAGAGAGAAAGGTTGCCCAAAGAATT
    CTTTCTAAAGTAAGAGAAGTAACAAATCAGGAATTTCCAGTTCAGGAAATAGACTACATT
    ACTTTGCATTTGTTAGCTAAGAGTCAACAATGTCAAAAAAATCAGAAGAATATTTCTGAA
    GAAGTTTTAAAAAAATCTTTATTTAAAACATTTCAGAATTTAGGATTAGATGATATGTAT
    AACTTTTCTTCAGATTTCCAACTAATTGAAGGATTGATAACTCATCTAATGACACTACAA
    GTACGTTTAGAAAGCCGGATTACCTTAAATAACCCTTTGGTAGATGAAATTAAACAGAAT
    TATAGTGATATATTCTTTATGACTAGAGAAATTCTTGCAAATATGGACAAGTTCTTGGAG
    TGGACAATATCAGATGATGAAGTAGCATATGTAAGTCTTCACTTTTTAGCTGCTATGGAA
    CGTAGCAAAGAGAGTACTAAGTTTAATATTCTTGCTATTTGTGCAACAGGATTTGGTGCA
    GCCCAAATGTTAAGAAATCGTTTGGAAACGGAGTTTGGGAAGCGAGTAGAAGTTGTTGAT
    GTAATAGGCTATTATGAATTGAATCAAGAAAAACTTAAAGGAATAGATTTTATAGTGTCA
    GCTGTTGATTTATCAAATCTATATTTTCAAATCCCAGTTTTTAAAGTTAGTGTGTTTCTT
    AAAAGTGATGAGATGGAAATGATTAGAAAAGCTATGGATCAGATGCAAGTTTCTAGTTAT
    GTACAATCATCAAAGATTAACAAATTTGAAAACAACAGCTTTAGACAGTATTTTAGTAAA
    GAAAATTTTTTAATATGTACTGAATCAGACAAGGTAAATTTACTTGAAAAGATGGTTGAG
    GGTTTATCTGTTGGTGAATCAAATGAGTTTGAACAATCTTTACTTTATGGAATTAAACAG
    CGCGAAGAATTAAGTTCAGTTGTTTTTTCTGAAAAAATTGCAGTTCCGCATCCTATTCAG
    CCCTTTGGTACAGAGGGAAAGGTTTCGGTTGCAATTTGTAAAGATTCGTTACTCTGGGAT
    AATCAAAGTTCACATGTCCAGCTAGTATTTCTTCTATCTCCATCAATATATGGGAACGAA
    GGTTTGGCAACTGTGACTAAAAAGATAGTCTCTCTGACAGAGAATGATGAATTGCAAAAT
    CAGCTAATATCTTGCAATAACTTTGAAGATTTTATTAACATATTTGAGAAGATAAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: T308_RS01540 [old locus tag: T308_01540 ]
  • symbol: T308_RS01540
  • description: BglG family transcription antiterminator
  • length: 659
  • theoretical pI: 5.00373
  • theoretical MW: 76537.3
  • GRAVY: -0.199545

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 34.2)
    Signal transduction Signal transduction PTS PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 34.2)
    and 6 more
    Signal transduction Signal transduction PTS PTS IIA-like nitrogen-regulatory protein PtsN (TIGR01419; HMM-score: 14.1)
    Unknown function General DNA binding domain, excisionase family (TIGR01764; HMM-score: 14)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other iron-sulfur cluster biosynthesis transcriptional regulator SufR (TIGR02702; HMM-score: 14)
    Signal transduction Regulatory functions DNA interactions iron-sulfur cluster biosynthesis transcriptional regulator SufR (TIGR02702; HMM-score: 14)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly SUF system regulator (TIGR02944; HMM-score: 12.7)
    Signal transduction Regulatory functions DNA interactions FeS assembly SUF system regulator (TIGR02944; HMM-score: 12.7)
  • TheSEED: data available for D39, TIGR4
  • PFAM:
    PRD (CL0166) PRD; PRD domain (PF00874; HMM-score: 126.5)
    and 22 more
    HTH (CL0123) HTH_11; HTH domain (PF08279; HMM-score: 75.2)
    Mga; Mga helix-turn-helix domain (PF05043; HMM-score: 53.4)
    PTase-anion_tr (CL0340) PTS_EIIA_2; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 (PF00359; HMM-score: 48.4)
    Phosphatase (CL0031) PTS_IIB; PTS system, Lactose/Cellobiose specific IIB subunit (PF02302; HMM-score: 25.8)
    HTH (CL0123) HTH_Mga; M protein trans-acting positive regulator (MGA) HTH domain (PF08280; HMM-score: 22.8)
    HTH_DeoR; DeoR-like helix-turn-helix domain (PF08220; HMM-score: 18.7)
    HrcA_DNA-bdg; Winged helix-turn-helix transcription repressor, HrcA DNA-binding (PF03444; HMM-score: 17.3)
    SgrR_N; Sugar transport-related sRNA regulator N-term (PF12793; HMM-score: 16.8)
    HTH_5; Bacterial regulatory protein, arsR family (PF01022; HMM-score: 16.6)
    HTH_10; HTH DNA binding domain (PF04967; HMM-score: 16.6)
    PuR_N; Bacterial purine repressor, N-terminal (PF09182; HMM-score: 16.4)
    HTH_17; Helix-turn-helix domain (PF12728; HMM-score: 15.8)
    MarR_2; MarR family (PF12802; HMM-score: 15.6)
    Trans_reg_C; Transcriptional regulatory protein, C terminal (PF00486; HMM-score: 15.2)
    Phage_CI_repr; Bacteriophage CI repressor helix-turn-helix domain (PF07022; HMM-score: 15.1)
    HTH_20; Helix-turn-helix domain (PF12840; HMM-score: 14.9)
    HTH_AraC; Bacterial regulatory helix-turn-helix proteins, AraC family (PF00165; HMM-score: 14.7)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 13.9)
    PH (CL0266) DM10_dom; DM10 domain (PF06565; HMM-score: 13.7)
    HTH (CL0123) Sigma70_r4_2; Sigma-70, region 4 (PF08281; HMM-score: 12.3)
    GerE; Bacterial regulatory proteins, luxR family (PF00196; HMM-score: 12)
    Beta-tent (CL0080) Mss4; Mss4 protein (PF04421; HMM-score: 10.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • genes regulated by 
    CelRTF important in Cellobiose utilization: in D39V
    CelR*TF important in Cellobiose utilization: in TIGR4

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9382
    • Cytoplasmic Membrane Score: 0.0575
    • Cell wall & surface Score: 0.0008
    • Extracellular Score: 0.0035
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004825
    • TAT(Tat/SPI): 0.000206
    • LIPO(Sec/SPII): 0.001868
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001101781 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLKLIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVFILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSGEERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDFVLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQEIDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLITHLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVSLHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQEKLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINKFENNSFRQYFSKENFLICTESDKVNLLEKMVEGLSVGESNEFEQSLLYGIKQREELSSVVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLATVTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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