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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 19-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Xen35
  • locus tag: CXP32_RS05745 [old locus tag: CXP32_05745 ]
  • pan locus tag?: PNEUPAN002295000
  • symbol: iga
  • pan gene symbol?: zmpA
  • synonym:
  • product: immunoglobulin A1 protease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: CXP32_RS05745 [old locus tag: CXP32_05745 ]
  • symbol: iga
  • product: immunoglobulin A1 protease
  • replicon: chromosome
  • strand: +
  • coordinates: 1083881..1089895
  • length: 6015
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP025256 (1083881..1089895) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    5761
    5821
    5881
    5941
    6001
    ATGGAAAAGTATTTTGGTGAAAAACAAGAGCGTTTTTCATTTAGAAAATTATCAGTAGGA
    CTTGTATCTGCAACGATTTCAAGTTTATTTTTTATGTCTGTATTAGCTAGTTCATCTGTG
    GATGCTCAAGAAACTGCGGGAGTTCACTATAAATATGTGGCAGATTCAGAGCTATCATCA
    GAAGAAAAGAAGCAGCTTGTCTATGATATTCCGACATACGTGGAGAATGATGATGAAACT
    TATTATCTTGTTTATAAGTTAAATTCTCAAAATCAACTGGCGGAATTGCCAAATACTGGA
    AGCAAGAATGAGAGGCAAGCCCTAGTTGCTGGTGCTAGCTTAGCTGCTATGGGAATTTTA
    ATTTTTGCTGTTTCCAAGAAAAAGGTTAAGAATAAAACGGTATTACATTTAGTATTGGTT
    GCAGGGATAGGAAATGGTGTCTTAGTTTCAGTCCATGCTTTAGAAAATCATCTTTTGCTA
    AATTACAATACGGACTATGAATTGACCTCTGGAGAAAAATTACCTCTTCCTAAAGAGATT
    TCAGGTTACACTTATATTGGATATATCAAAGAGGGAAAAACGACTTCTGAGTCTGAAGTA
    AGTAATCAAAAGAGTTCAGTTGCCACTCCTACAAAACAACAAAAGGTGGATTATAATGTT
    ACACCGAATTTTGTAGACCATCCATCAACAGTACAAGCTATTCAGGAACAAACACCTGTT
    TCTTCAACTAAGCCGACAGAAGTTCAAGTAGTTGAAAAACCTTTCTCTACTGAATTAATC
    AATCCAAGAAAAGAAGAGAAACAATCTTCAGATTCTCAAGAACAATTAGCCGAACATAAG
    AATCTAGAAACGAAGAAAGAGGAGAAGATTTCTCCAAAAGAAAAGACTGGGGTAAATACA
    TTAAATCCACAGGATGAAGTTTTATCAGGTCAATTGAACAAACCTGAACTCTTATATCGT
    GAGGAAACTATGGAGACAAAAATAGATTTTCAAGAAGAAATTCAAGAAAATCCTGATTTA
    GCTGAAGGAACTGTAAGAGTAAAACAAGAAGGTAAATTAGGTAAGAAAGTTGAAATCGTC
    AGAATATTCTCTGTAAACAAGGAAGAAGTTTCGCGAGAAATTGTTTCAACTTCAACGACT
    GCGCCTAGTCCAAGAATAGTCGAAAAAGGTACTAAAAAAACTCAAGTTATAAAGGAACAA
    CCTGAGACTGGTGTAGAACATAAGGACGTACAGTCTGGAGCTATTGTTGAACCCGCAATT
    CAGCCTGAGTTGCCCGAAGCTGTAGTAAGTGACAAAGGCGAACCAGAAGTTCAACCTACA
    TTACCCGAAGCAGTTGTGACCGACAAAGGTGAGACTGAGGTTCAACCAGAGTCGCCAGAT
    ACTGTGGTAAGTGATAAAGGTGAACCAGAGCAGGTAGCACCGCTTCCAGAATATAAGGGT
    AATATTGAGCAAGTAAAACCTGAAACTCCGGTTGAGAAGACCAAAGAACAAGGTCCAGAA
    AAAACTGAAGAAGTTCCAGTAAAACCAACAGAAGAAACACCAGTAAATCCAAATGAAGGT
    ACTACAGAAGGAACCTCAATTCAAGAAGCAGAAAATCCAGTTCAACCTGCAGAAGAATCA
    ACAACGAATTCAGAGAAAGTATCACCAGATACATCTAGCAAAAATACTGGGGAAGTGTCC
    AGTAATCCTAGTGATTCGACAACCTCAGTTGGAGAATCAAATAAACCAGAACATAATGAC
    TCTAAAAATGAAAATTCAGAAAAAACTGTAGAAGAAGTTCCAGTAAATCCAAATGAAGGC
    ACAGTAGAAGGTACCTCAAATCAAGAAACAGAAAAACCAGTTCAACCTGCAGAAGAAACA
    CAAACAAACTCTGGGAAAATAGCTAACGAAAATACTGGAGAAGTATCCAATAAACCTAGT
    GATTCAAAACCACCAGTTGAAGAATCAAATCAACCAGAAAAAAACGGAACTGCAACAAAA
    CCAGAAAATTCAGGTAATACAACATCAGAGAATGGACAAACAGAACCAGAACCATCAAAC
    GGAAATTCAACTGAGGATGTTTCAACCGAATCAAACACATCCAATTCAAATGGAAACGAA
    GAAATTAAACAAGAAAATGAACTAGACCCTGATAAAAAGGTAGAAGAACCAGAGAAAACA
    CTTGAATTAAGAAATGTTTCCGACCTAGAGTTATACAGTTTGTCAAATGGTACTTATAAA
    CAACACATTTCGTTAGAGCAAGTTCCAAGCAATCCAAATAGCTACTTTGTTAAAGTGAAA
    TCTTCTTCATTCAAAGATGTATACCTACCAGTAGCATCAATATCAGAGGAAAGAAAAAAT
    GATAAAATCCTTTATAAAATCACAGCAAAAGTAGAGAAGCTTCAGCAGGAGATAGAAAGC
    AGATATAAAGATAATTTTACCTTCTATCTAGCTAAGAAGGGAACAGAAGAAACAACAAAC
    TTTACTTCCTTTAGTAATCTGGTCAAAGCTATAAACCAAAATCCCTCTGGAACCTATCAT
    TTAGCGGCCAGCCTGAATGCTAACGAAGTGGAGCTTGGTCCTGATGAAAGATCCTATATC
    AAGGACACCTTTACTGGTCGTTTAATCGGTGAAAAAGATGGCAAGAATTATGCTATCTAT
    AATTTGAAAAAACCTCTGTTTGAAAACTTGAGTGGTGCTACAGTAGAAAAACTGAGTCTA
    AAAAATGTTGCTATTTCAGGGAAAGATGATATCGGTTCACTGGCAAATGAAGCTCAGAAT
    AACACAAAAATTAAGCAAGTTCACGTCGATGGTGTTCTGGCTGGTGAACGTGGTATCGGT
    GGTTTGCTGGCTAAGGCTGAGCAATCAAGCATCACAGAGAGCAGTTTCAAGGGAAGAATT
    ATCAACACTTATGAAACGACTGCTGCCTACAATATCGGTGGTATGGTCGGTCATTTGACA
    GGTGACAAGGCTTTACTTACTAAGTCAAAAGCGACAGTAGCCATTTCATCTAACACAAAT
    ACTTCAGATCAGACTGTGGGTGGACTTGCAGGCCTAGTAGACCGAGATGCACAGATCCAA
    GATAGCTATGCTGAAGGTGATATCAACAATGTCAAGCACTTTGGTAGAGTCGCTGGAGTG
    GCAGGCAATTTGTGGGATCGAACTTCTGGTGATGTTAGGCATGCTGGAAGTTTGACCAAT
    GTTCTCAGCGATGTTAATGTAACCAACGGAAATGCCATCACTGGTTACCACTATAACGAA
    ATGAAGGTAAAGGACACATTCAGCAGCAAGGCCAACAGAGTCTACAATGTCACCTTGGTC
    AAGGATGAGGTCGTCAGCAAGGAATCCTTTGAAGAAAGAGGAACAATGCTAGATGCTTCT
    CAAATTGCAAGCAAAAAAGCAGAAATCAATCCTCTCATTTTACCAACAGTGGAGCCACTT
    TCAACAAGTGGCAAAAAAGACAGTGATTTTTCTAAGGTGGCCTATTATCAAGCTAAGCGC
    AACTTGACTTATAAAAACATTGAAAAATTGCTACCTTTCTACAACAAGGCAACCATCGTC
    AAATACGGAAACCTGGTCAATGAGAACAGTCTTTTATATCAAAAAGAACTCTTGTCAGCA
    GTCATGATGAAGGACAACCAAGTCATCACAGACATTGTTTCTAACAAACAGACTGCAAAC
    AAACTCTTGCTTCACTACAAGGATGATTTATCTGAGAAGCTGGATCTCAAATACCAGAAT
    GATTTCGCCAAATTAGCAGAATATAGTCTGGGCAATACTGGACTTCTCTATACGCCAAAC
    CAATTCCTGTATGACCAAACCTCTATCATCAAGCAAGTCTTACCTGACTTACAAAAGGTT
    GACTATCATTCAGAAGCCATCAGAAAGACGCTGGGTATTTCTCCAAACGTCAAGCAAACT
    GAGCTCTATCTAGAAGACCAGTTCGCCAAAACAAAACAACAACTGGAAGACAGTTTGAAA
    AAACTCTTGTCAGCGGATGCTGGACTGGCTAGTGCTAACCCCGTCACTGAAGGTTATCTT
    GTAGATAAAATCAAACGCAACAAGGAAGCCTTGCTACTTGGCTTGACCTATCTGGAACGG
    TGGTATAACTTTAGCTATGGTCAGGTGAATGTCAAAGACCTAGTTCTGTACCATTTGGAC
    TTCTTTGGTAAGGGGAATGCTTCACCATTAGATACTCTGATTGAGTTGGGTAAATCTGGC
    TTTAACAATCTTCTAGCTAAGAATAATGTCGATACTTATGGTATCAGTCTTGCCAGTCAA
    CATGGAACGACAGATTTGTTTAGCACGCTGGAACATTACCGAAAAGTCTTTTTACCAAAT
    ACAAGCAATAATGACTGGTTTAAATCAGAGACTAAGGCTTACATTGTCGAAGAAAAATCC
    ACTATCGAAGAGGTGAAAACGAAGCAAGGGTTAGCTGGCACCAAGTATTCTATCGGTGTT
    TATGATCGTATCACGAGTGCCACATGGAAATACCGCAATATGGTCTTGCCTCTCCTGACC
    TTGCCAGAGAGATCCGTATTTGTCATCTCGACCATGTCTAGTCTAGGATTTGGAGCTTAT
    GATCGCTACCGCAGTAGTGACCATAAAGCGGGCAAGGCTCTCAATGATTTTGTTGAAGAA
    AATGCGCGTGAAACAGCCAAACGTCAGCGAGATCACTACGATTATTGGTATCGTATTTTA
    GACGACAATGCACGTGAAAAACTTTATAGAAATATTTTGCTTTACGATGCTTATAAATTT
    GGCGATGATAATACCGTAGGGAAAGCTACAGAAGTGGCAGATTTTGATAATCCAAATCCT
    GCAATGCAACATTTCTTTGGACCTGTTGGAAATAAAGTTGGGCATAATCAACACGGTGCT
    TATGCTACAGGTGATGCAGTTTATTATATGGGTTATCGAATGTTGGATAAGGATGGAGCT
    ATTACTTATACGCATGAGATGACACATGACTCAGATCAGGACATTTATCTTGGAGGATAT
    GGTCGAAGAAGTGGCTTGGGACCAGAGTTCTTTGCTAAAGGATTATTACAAGCACCAGAC
    CATCCAGATGATGCGACCATTACCATCAACTCCATCTTGAAACATTCAAAATCTGATAGT
    ACAGAAAGTCGACGATTACAAGTACTTGATCCAACTACAAGATTTAATAATGCAGATGAT
    TTGAAGCAATATGTCCACAACATGTTTGACGTTGTTTATATGTTGGAATATCTCGAAGGA
    AATTCAATTCTTAAATTGGATACGAATCAAAAACAACAACTTCTTAGAAAAGTTACAAAT
    GAGTACCATCCTGATCCTGATGGAAATAAGGTCTATGCAACAAATGTTGTCAGAAATCTA
    ACAGTAGAAGAAGTTGAAAGACTACGTTCATTCAATGATTTGATTGATAATAATATTCTT
    TCGTCTAGGGAATATGCCTCAGGTAAATACGAAAGAAATGGCTACTTCACTATTAAGTTA
    TTTGCACCGATTTATGCTGCATTAAGTAATGATATAGGAACACCAGGTGACCTGATGGGA
    CGTCGTATAGCCTATGAACTACTAGCTGCTAAAGGCTTTAAAGATGGTATGGTACCATAT
    ATCTCAAACCAATACGAAGAAGAAGCCAAACAAAAGGGCAAGACAATCAATCTCTACGGT
    AAAACAAGAGGTTTGGTTACAGATGACTTGGTTTTGGAAAAGGTATTTAATAACCAATAT
    CATACTTGGAGTGAGTTTAAGAAAGCTATGTATCAAGAACGACAAGATCAGTTTGATAGA
    TTGAACAAAGTTACTTTTAATGATACAACACAGCCTTGGCAAACATTTGCCAAGAAAACT
    ACAAGCAGTGTAGATGAATTACAGAAATTAATGGACGTTGCTGTTCGTAAGGATGCAGAA
    CACAATTACTACCATTGGAATAACTACAATCCAGACATAGATAGTGAAGTCCACAAGCTC
    AAGAGAGCAATCTTTAAAGCCTATCTTGACCAAACAAATGATTTTAGAAGTTCAATTTTT
    GAGAATAAAAAATAG
    60
    120
    180
    240
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    660
    720
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    840
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    2160
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    4140
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    5640
    5700
    5760
    5820
    5880
    5940
    6000
    6015

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: CXP32_RS05745 [old locus tag: CXP32_05745 ]
  • symbol: Iga
  • description: immunoglobulin A1 protease
  • length: 2004
  • theoretical pI: 5.02992
  • theoretical MW: 223907
  • GRAVY: -0.716118

⊟Function[edit | edit source]

  • TIGRFAM:
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 44.4)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 20.7)
  • TheSEED: data available for D39, TIGR4
  • PFAM:
    no clan defined Peptidase_M26_C; M26 IgA1-specific Metallo-endopeptidase C-terminal region (PF07580; HMM-score: 1029.1)
    and 6 more
    Peptidase_M26_N; M26 IgA1-specific Metallo-endopeptidase N-terminal region (PF05342; HMM-score: 271.7)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 56.3)
    no clan defined Glug; The GLUG motif (PF07581; HMM-score: 36.2)
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 36)
    Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 28.1)
    PELOTA (CL0101) RbsD_FucU; RbsD / FucU transport protein family (PF05025; HMM-score: 9.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 2
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.0035
    • Cell wall & surface Score: 0.85
    • Extracellular Score: 0.1463
  • SignalP: Signal peptide SP(Sec/SPI) length 42 aa
    • SP(Sec/SPI): 0.91723
    • TAT(Tat/SPI): 0.067255
    • LIPO(Sec/SPII): 0.005174
    • Cleavage Site: CS pos: 42-43. VDA-QE. Pr: 0.9143
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000417180 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAAMGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSESEVSNQKSSVATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETMETKIDFQEEIQENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTKKTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKGETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSKNTGEVSSNPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGNSTEDVSTESNTSNSNGNEEIKQENELDPDKKVEEPEKTLELRNVSDLELYSLSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEIESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNPSGTYHLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEKLSLKNVAISGKDDIGSLANEAQNNTKIKQVHVDGVLAGERGIGGLLAKAEQSSITESSFKGRIINTYETTAAYNIGGMVGHLTGDKALLTKSKATVAISSNTNTSDQTVGGLAGLVDRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYNEMKVKDTFSSKANRVYNVTLVKDEVVSKESFEERGTMLDASQIASKKAEINPLILPTVEPLSTSGKKDSDFSKVAYYQAKRNLTYKNIEKLLPFYNKATIVKYGNLVNENSLLYQKELLSAVMMKDNQVITDIVSNKQTANKLLLHYKDDLSEKLDLKYQNDFAKLAEYSLGNTGLLYTPNQFLYDQTSIIKQVLPDLQKVDYHSEAIRKTLGISPNVKQTELYLEDQFAKTKQQLEDSLKKLLSADAGLASANPVTEGYLVDKIKRNKEALLLGLTYLERWYNFSYGQVNVKDLVLYHLDFFGKGNASPLDTLIELGKSGFNNLLAKNNVDTYGISLASQHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYSIGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALNDFVEENARETAKRQRDHYDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVGNKVGHNQHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPDDATITINSILKHSKSDSTESRRLQVLDPTTRFNNADDLKQYVHNMFDVVYMLEYLEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNLTVEEVERLRSFNDLIDNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDIGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEEAKQKGKTINLYGKTRGLVTDDLVLEKVFNNQYHTWSEFKKAMYQERQDQFDRLNKVTFNDTTQPWQTFAKKTTSSVDELQKLMDVAVRKDAEHNYYHWNNYNPDIDSEVHKLKRAIFKAYLDQTNDFRSSIFENKK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Jeffrey N Weiser, Deborah Bae, Claudine Fasching, Ronald W Scamurra, Adam J Ratner, Edward N Janoff
Antibody-enhanced pneumococcal adherence requires IgA1 protease.
Proc Natl Acad Sci U S A: 2003, 100(7);4215-20
[PubMed:12642661] [WorldCat.org] [DOI] (P p)Damiana Chiavolini, Guido Memmi, Tiziana Maggi, Francesco Iannelli, Gianni Pozzi, Marco R Oggioni
The three extra-cellular zinc metalloproteinases of Streptococcus pneumoniae have a different impact on virulence in mice.
BMC Microbiol: 2003, 3;14
[PubMed:12841855] [WorldCat.org] [DOI] (I e)E N Janoff, J B Rubins, C Fasching, D Charboneau, J T Rahkola, A G Plaut, J N Weiser
Pneumococcal IgA1 protease subverts specific protection by human IgA1.
Mucosal Immunol: 2014, 7(2);249-56
[PubMed:23820749] [WorldCat.org] [DOI] (I p)H Lomholt
Evidence of recombination and an antigenically diverse immunoglobulin A1 protease among strains of Streptococcus pneumoniae.
Infect Immun: 1995, 63(11);4238-43
[PubMed:7591053] [WorldCat.org] [DOI] (P p)K Poulsen, J Reinholdt, M Kilian
Characterization of the Streptococcus pneumoniae immunoglobulin A1 protease gene (iga) and its translation product.
Infect Immun: 1996, 64(10);3957-66
[PubMed:8926055] [WorldCat.org] [DOI] (P p)J H Wani, J V Gilbert, A G Plaut, J N Weiser
Identification, cloning, and sequencing of the immunoglobulin A1 protease gene of Streptococcus pneumoniae.
Infect Immun: 1996, 64(10);3967-74
[PubMed:8926056] [WorldCat.org] [DOI] (P p)

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