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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 08-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae BVJ1JL
  • locus tag: JN057_RS05775 [old locus tag: JN057_01192 ]
  • pan locus tag?: PNEUPAN002295000
  • symbol: zmpA
  • pan gene symbol?: zmpA
  • synonym: iga
  • product: zinc metalloprotease A

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JN057_RS05775 [old locus tag: JN057_01192 ]
  • symbol: zmpA
  • product: zinc metalloprotease A
  • replicon: chromosome
  • strand: +
  • coordinates: 1121581..1128060
  • length: 6480
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP071871 (1121581..1128060) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
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    481
    541
    601
    661
    721
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    1021
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    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
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    2581
    2641
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    3001
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    4441
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    4561
    4621
    4681
    4741
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    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
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    5881
    5941
    6001
    6061
    6121
    6181
    6241
    6301
    6361
    6421
    ATGGAAAAGTATTTTGGTGAAAAACAAGAGCGTTTTTCATTTAGAAAATTATCAGTAGGA
    CTTGTATCTGCAACGATTTCAAGTTTATTTTTTATGTCTGTATTAGCTAGTTCATCTGTG
    GATGCTCAAGAAACTGCGGGAGTTCACTATAAATATGTGGCAGATTCAGAGCTATCATCA
    GAAGAAAAGAAGCAGCTTGTCTATGATATTCCGACATACGTGGAGAATGATGATGAAACT
    TATTATCTTGTTTATAAGTTAAATTCTCAAAATCAACTGGCGGAATTACCAAATACTGGA
    AGCAAGAATGAGAGGCAAGCCCTAGTTGCTGGTGCTAGCTTAGCTGCTCTGGGAATTTTA
    ATTTTTGCTGTTTCCAAGAAAAAGGTTAAGAATAAAACGGTATTACATTTAGTATTGGTT
    GCGGGAATGGGAAATGGTGTCTTAGTTTCAGTCCATGCTTTAGAAAATCATCTTTTGCTA
    AATTACAATACGGACTATGAATTGACCTCTGGAGAAAAATTACCTCTTCCTAAAGAGATT
    TCAGGTTACACTTATATTGGATATATCAAAGAGGGAAAAACGACTTCTGATTTTGAAGTA
    AGTAATCAAGAAAAATCAGCAGCCACTCCTACAAAACAACAAAAGGTGGATTATAATGTT
    ACACCAAATTTTGTAGACCATCCATCAACAGTACAAGCTATTCAGGAACAAACACCTGTT
    TCTTCAACTAAGCCGACAGAAGTTCAAGTAGTTGAAAAACCTTTCTCTACTGAATTAATC
    AATCCAAGAAAAGAAGAGAAACAATCTTCAGATTCTCAAGAACAATTAGCCGAACATAAG
    AATCTAGAAACGAAGAAAGAGGAGAAGATTTCTCCAAAGGAAAAGACTGGGGTAAATACA
    TTAAATCCACAGGATGAAGTGCTATCAGGTCAGTTGAACAAACCGGAACTCTTATATCGT
    GACGAAACTATAGAAACAAAAATAGATTTTCAAGAAGAAATTCAAGAAAATCCTGATTTA
    GCAGAAGGAACTGTAAGAGTAAAACAAGAAGGTGCATTAGGTAAGAAAGTTGAAATCGTC
    AGAATATTTTCTGTAAACAATGAAGAAGTTTCACGAGAAATTATTTCAACTTCAACGACT
    GCGCCTGTTTCAAGAATAGTCGAAAAAGGTACTAAAAAAGCTCAAGTTATAAAGGAACAA
    GCTGAGACTGGTGCAGAACATAAGGAAGTACAGTCTGGAGCTATTGTTGAACCCGCAATT
    CAGCCTGAACTACCAGCAGCTGTATTAACCGACAAAGGTGAGTCAGCAGTCCAACCAGAG
    TTGCCAGAAGCTGTAGTAAGTGATAAAGGCGTACCAGAAGTTCAACCAGCGTTACCAGAG
    GCAGTCATGACTGACAAGGGTGATCCAGAGCAGGTAGAACCGCTACCAGAATATACAGGA
    GTACAAGCTGGAGCTATTGTTGAACCTGAAAAAGTTGAACCGGAATATGCTGGAGTACAA
    GCTGGCGCTATTGTTGAACCAGAGCAGGTAGCACCACTACCAGAATACACAGGGGTGCAA
    GCCGGAGCGATAGTCGAGCCAGAGAAAGTAGAAGCACCGAAGGAATACACAGGAGTGCAG
    GCTGGAGCGATAGTCGAACCAGAGAAGGTAGAAGCACCGAAGGAATACACAGGAGTGCAA
    GCCGGAGCAATAGTAGAACCAGAAAAAGTAGAACCATCAAAAGAATACACAGGGGTGCAG
    GCTGGCGCTATTGTTGAACCAGAGCAGATAGCACCACTACCAGAATACACAGGGGTGCAA
    GCCGGAGCGATAGTCGAGCCAGAGAAAGTAGAAGCACTGAAAGAATATACTGGTAAAATC
    GAACAACCTAGTGCAGAAGATACTAAACCAAATAATGAAAATACTAATACACCAGAAGAA
    ATGAGTATTCAGAAAAAATCTAGTGCATTAATTAATATGAACTTTATTACAGATTCGTCG
    AAGGTTACTGGAGTAGGATCAGCTACTTTTATTGCACCAAATGTACTTTTAACAGTAGCA
    CATAATTTCATTAATAATTCTACTGATAATACTACTGGCGAATTTAGAGGTGATAAATCT
    AAAAACGTATATGAGTGGGTGACTCCTGATGGACAAAAAGGAACATTTACTGCTAACAAT
    ATTCATTTTTATAATAAAAAAGATTATCCAAAAGGATTTATCTATGATTTAGCAGTGATT
    AAGCTACCTGAAACAACTGGCAGAGAACATGTAGAATTAGTTAAAAATTATTCGAAAGTA
    AATCTTAATGACAAACTAAATGTTCATGGATATCCAGCTGGGAAATATACGCACTTAAAA
    GATGCTACGGTAGAAATGGAACAAGAATATGCGAATAACACCTACGGTGTTCAATATCAA
    GGTGGAAATCCTGGTATGAGTGGTGGAGGAATATTTAATGCTAATGGTGAAGTTATTGGT
    GTGCATCAAAATGGAGCACAAAATCGCTCAGGCGGATTGATTTTATCTCCTACACAATTA
    GCTTGGATTAAGAGTATTATAGCAGGTAATGAAATTCCACCAGTATACGATGAACTTTAT
    CGTCATAAAGATGAGAAAAAAGATGACGCTAAAGATGAAAAAGAAGTTATTAAGAAATTA
    GAACTTAGAAATATATCTTCTGTAGAACTATATTCAAAAGATGGTAATAAGTATCGACAT
    GTAACTTCACTTGCTTCTTTACCAAGTAATGCAGAAAATTACTTTATGAAAGTTAAATCA
    GAGAACTTTAAAGATGTGATGCTACCAGTTACAAGCATTACTAATGATACTAAAGATAAT
    AGAGATGTTTATAAGATAGTAGCAAGTGCAAATAGTCTGATACAACATGAAAATAATAAT
    GTACTAGAAAATTATACATACTATTTACCAAAAACTCAGCAAAGTGAAACTGGGGTATAT
    ACATCATTTAAAAATTTAGTAGATGCAATGAATAGCAATCCTAATGGCACATTCCGTTTA
    GGAGCAACTATGGATGCTCGTGAAGTTGAACTTCCAGATGGTCAAGAAAGTTATGTGAAT
    AATGTATTCCATGGAATATTAGTAGGAACAAATAATGAGAAATATTATGCTATTTATAAT
    TTGAAAAAACCATTATTTGGGGAATTAAATGGTGCTACAGTAGAAAAACTTTCACTAAAA
    GATGTTAATATTTCCGCAAAGGACGATACTGCAACACTTGCGAAAGAAGCAAATAACAAT
    ACTCATATTGATAACGTTCATGCTGATGGAGCGATAGCTGGGGAACGTAGCATAGGAGGA
    TTAGTATCACAAGTTAATAATTCTACTATTTCTAACAGTAGCTATACAGGTAGAATAACT
    AATACATATAAAACAGTTGCTAGTTATCAAATCGGAGGTTTAGTAGGCAAACTTTCTGGT
    CCGAGGGGATTAATAGATAAGTCGTTCGCATCAATCGATTTATCTTCAAATGCAACACAA
    GGAGACCAGTCTATTGGTGGAATAGTTGGTGCAGTAGAAAATAGTGCGCTTATTAGTAAT
    AGTTATGCTGAAGGAAATCTAAATAATGTTCAACGTTTTGCAAACGTTGGTGGAGTAGTT
    GGTAATCTTTGGGATCCGGTTGGAGGATTAGAAAAATCCGGTCGACTTTCTAATGTACTA
    AGCGATGTTAATGTAACGAATGGTAATGCTATTGCAGGTTATAATTTTAATGGTATAAAA
    GCAAATGGCACATACAGTAATAAAAATAATAAGGTTGTGAACGTAGTACAAGAAGATGAT
    GAAATCTTAACTAAGGATTCTACTGTTCAAAGAGGAGAAGTATTAGAAGATGCACAAATA
    AAAGAGAAAAAAGCTACTTTTGTATCTAAAAATACTATTAAAACAGAAGATTTTAATTTC
    TCTTCTAGATATGTAACTGACTATAAAAATCTTGAGAATGCTGATTCATCAAAAGAAAAA
    GTATATAAAAATATTGAAAAACTATTACCGTTTTATAATAGAGAAACAATTGTTAAGTAC
    GGAAATTTAGTAGAGACAAGTAGTAATCTTTATAATAAAGAATTATTGTCAGTAGTCCCT
    ATGAAAGATAAAGAAGTAATTAGTGATATTAACAAAAATAAATCAAGTATAAATAAACTA
    TTACTATATTACGCGGATAATACATCAGAGACACTTAATGTAAATTATCAAACTGATTTT
    TCAAATGTAGCAGAGTATAGAATAGGCGGTACAAACTTAATTTATACACCGAATACATTA
    CTTCGCAATTATCAAAATATTTTAGATGAAGTATTACCAGCATTAAATAGTGTAGAATAT
    AAATCAGAGGCAATTAGAAAAGTATTAGATGTTTCTAAGGATGTTAGTTTAACGGAGTTA
    TATTTAGAAGAACAATTCAATACCACAAAAACTAATTTGAAAGATAGTTTGACAAAACTT
    CTTACTGCAGATGCTGCAATAGCTGAAAATAACAATAAGGTAATAGATAATTATGTAATC
    GAGAAAATTAAAAATAATAAAGAAGCTTTACTTCTAGGATTAACATACTTAGAGCGTTGG
    TACGACTTCAAATATCGTGATACAAAAGCGAAAGATTTAGTCATGTACCACTTGGATTTC
    TTCGGTAAATCAAATAGTTCAGCGTTAGATAATGTTATCGAACTAGGTAAATCGGGATAT
    AATAACTTACTAGCAAAAAATAATGTTATAACTTATAATGTTTTATTAGCGAAAAATTAT
    AAGACTAATAATTTATTTGATGCATTAGAGAAATATAGAAAAGCATTTGTACCAGATAAA
    ACAAATAATGAGTGGTTTAAAGAACAAACTAAAGCATATATTGTAGAAGAAAAATCTACT
    ATTAAAGAGGTAAGTGATAAGCAATCAATAGCTGGTAGTCCATATTCAATTGGAGTATAT
    GATAGATTAACTAGCCCATCTTGGAAATATCCAAGTATGGTGTTGCCGCTATTAACATTA
    CCTGAAAAATCGGTGTTTATTATAGCCAACATTTCGACTATAGGTTTCGGTGCTTATGAT
    AGATATAGAAGTAAAGAACATCCAGCAGGAACTGATTTAAATGACTATGTTGAGAAAAAA
    GCTAAAGAAGCGGCTGTTAGATTTAGAGATCACTATGATTATTGGTATAGAATACTAGAT
    GATAAAAATAAAGAAAAATTATATAGAAGTGTTCTAGTCTATGATGCATTTAGATTTGGT
    ACAGATGAAAAAGAAGATAAAGATACATATCAAGCAACTTTTGAAACTAATCATCCAGCT
    ATAAAACATTTCTTCGGTCCAGCGGGAAATAATGTTGTTCATAATTCTAATGGAGCATAT
    GCTACAGGGGATGCATTCTATTATATGGCATATCGCATGCTTGATAAAGATGGTGCGGTA
    ACTTATACACACGAAATGACACATAACTCAGATAGAGAAATTTATCTTGGAGGCTATGGA
    AGACGAAATGGACTTGGACCAGAGTTTTATGCTAAAGGACTGCTACAAGCTCCTGATCAT
    CCTAATGATCCAACAGTCACTATTAATTCCATATTAAAATATGATCAATCAGAAGAATCA
    ACAAGGCTTCAAGTAGCAGATCCAACTCAACGATTTGGAAGTGTTGATGATCTAAATAAG
    TATATGCATAATATGTTTGATGTAATATACATGCTTGAAATACTAGAAGGTAAAGCTGTA
    GCTAAATTAGATACAAATCAAAAATATGATTTATTAAGAAAAATAGAAAATGAATATAAA
    CCTGATCCTGATGGAAATTCTGTTTATGCAACGAATGTTGTACGTAGATTAAAACCAGAA
    GAACTTACTAAATTAACTACATTTAACAGTTTGATAGAACATGATATTATAACAAGAAGA
    GGTTATGTAGATGAAGCAACTTATAAGCGGAATGGCTACTATACAATTAATCTATTCTCA
    CCAATTTATTCAGCATTGAGCAGTAAAATAGGAACACCAGGAGATTTAATGGGACGACGT
    ATTGCATTTGAGTTATTGGCAGCCAAGGGGTACAAAGACGGTATGGTTCCATATATTTCT
    AATCAGTATGAAAAAGAAGCGAAAGCTCAAGGAAAAGTTATTACATCATATGGTAAACAA
    ATAGGTTTAGTTACTGATGAAATTGTTCTTTCAAAAGTATTTAATAACCAGTATAATTCT
    TGGATAGATTTCAAGAAAGATATGTATAAAGAAAGAGAAGATAAATTTGGAAAGTTAAAT
    AAAGTTAGTTTTATCGATCCAAACGGTTCTTGGGCTCGACAACAGAAAGTGACTATTGAT
    AATATTAATAGACTTGAAAAAATGATTGAAGATGCAGTAAAATTTGATGCTGAGGATGAA
    GTTGCCAAATTATATCCTGAGACAAATAGTAGAGTTCTTAAACTGAAAAAAGCAATCTTT
    AAAGCTTATCTTGACCAAACCGGTGATTTTAGAAGTTCAATTTTTGAGAATAAAAAATAG
    60
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⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JN057_RS05775 [old locus tag: JN057_01192 ]
  • symbol: ZmpA
  • description: zinc metalloprotease A
  • length: 2159
  • theoretical pI: 5.11398
  • theoretical MW: 240803
  • GRAVY: -0.560723

⊟Function[edit | edit source]

  • TIGRFAM:
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 44.2)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 21.1)
  • TheSEED: data available for D39, TIGR4
  • PFAM:
    no clan defined Peptidase_M26_C; M26 IgA1-specific Metallo-endopeptidase C-terminal region (PF07580; HMM-score: 874)
    and 7 more
    Peptidase_M26_N; M26 IgA1-specific Metallo-endopeptidase N-terminal region (PF05342; HMM-score: 267.9)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 60)
    no clan defined YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 36.9)
    Peptidase_PA (CL0124) Trypsin_2; Trypsin-like peptidase domain (PF13365; HMM-score: 35.6)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 29.4)
    Glug; The GLUG motif (PF07581; HMM-score: 24.5)
    Peptidase_PA (CL0124) Trypsin; Trypsin (PF00089; HMM-score: 24)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 2
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.0044
    • Cell wall & surface Score: 0.717
    • Extracellular Score: 0.2785
  • SignalP: Signal peptide SP(Sec/SPI) length 42 aa
    • SP(Sec/SPI): 0.91723
    • TAT(Tat/SPI): 0.067255
    • LIPO(Sec/SPII): 0.005174
    • Cleavage Site: CS pos: 42-43. VDA-QE. Pr: 0.9143
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000417162 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEIQENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTKKAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKGVPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPEQVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENYFMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKTQQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGTNNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHADGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLIDKSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLWDPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEILTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEKVYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSINKLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALNSVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKVIDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNVIELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQTKAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFIIANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEKLYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPNDPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAVAKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIITRRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMVPYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKEREDKFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRVLKLKKAIFKAYLDQTGDFRSSIFENKK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Jeffrey N Weiser, Deborah Bae, Claudine Fasching, Ronald W Scamurra, Adam J Ratner, Edward N Janoff
Antibody-enhanced pneumococcal adherence requires IgA1 protease.
Proc Natl Acad Sci U S A: 2003, 100(7);4215-20
[PubMed:12642661] [WorldCat.org] [DOI] (P p)Damiana Chiavolini, Guido Memmi, Tiziana Maggi, Francesco Iannelli, Gianni Pozzi, Marco R Oggioni
The three extra-cellular zinc metalloproteinases of Streptococcus pneumoniae have a different impact on virulence in mice.
BMC Microbiol: 2003, 3;14
[PubMed:12841855] [WorldCat.org] [DOI] (I e)E N Janoff, J B Rubins, C Fasching, D Charboneau, J T Rahkola, A G Plaut, J N Weiser
Pneumococcal IgA1 protease subverts specific protection by human IgA1.
Mucosal Immunol: 2014, 7(2);249-56
[PubMed:23820749] [WorldCat.org] [DOI] (I p)H Lomholt
Evidence of recombination and an antigenically diverse immunoglobulin A1 protease among strains of Streptococcus pneumoniae.
Infect Immun: 1995, 63(11);4238-43
[PubMed:7591053] [WorldCat.org] [DOI] (P p)K Poulsen, J Reinholdt, M Kilian
Characterization of the Streptococcus pneumoniae immunoglobulin A1 protease gene (iga) and its translation product.
Infect Immun: 1996, 64(10);3957-66
[PubMed:8926055] [WorldCat.org] [DOI] (P p)J H Wani, J V Gilbert, A G Plaut, J N Weiser
Identification, cloning, and sequencing of the immunoglobulin A1 protease gene of Streptococcus pneumoniae.
Infect Immun: 1996, 64(10);3967-74
[PubMed:8926056] [WorldCat.org] [DOI] (P p)

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