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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 16-MAY-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae EF3030
  • locus tag: EF3030_04840 [new locus tag: EF3030_RS04840 ]
  • pan locus tag?: PNEUPAN002079000
  • symbol: phtE
  • pan gene symbol?: phtE
  • synonym:
  • product: pneumococcal histidine triad protein PhtE

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EF3030_04840 [new locus tag: EF3030_RS04840 ]
  • symbol: phtE
  • product: pneumococcal histidine triad protein PhtE
  • replicon: chromosome
  • strand: +
  • coordinates: 904472..907570
  • length: 3099
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    ATAGCAGCTGGATCAGCTGTTATCGTATCCTTGAGTTTATGTGCCTATGCACTAAACCAG
    CATCGTTCGCAGGAAAATAAGGACAATAATCGTGTCTCTTATGTGGATGGCAGCCAGTCA
    AGTCAGAAAAGTGAAAACTTGACACCAGACCAGGTTAGCCAGAAAGAAGGAATTCAGGCT
    GAGCAAATTGTAATCAAAATTACAGATCAGGGCTATGTAACGTCACACGGTGACCACTAT
    CATTACTATAATGGGAAAGTTCCTTATGATGCCCTCTTTAGTGAAGAACTCTTGATGAAG
    GATCCAAACTATCAACTTAAAGACGCTGATATTGTCAATGAAGTCAAGGGTGGTTATATC
    ATCAAGGTCGATGGAAAATATTATGTCTACCTGAAAGATGCAGCTCATGCTGATAATGTT
    CGAACTAAAGATGAAATCAATCGTCAAAAACAAGAACATGTCAAAGATAATGAGAAGGTT
    AACTCTAATGTTGCTGTAGCAAGGTCTCAGGGACGATATACGACAAATGATGGTTATGTC
    TTTAATCCAGCTGATATTATCGAAGATACGGGTAATGCTTATATCGTTCCTCATGGAGGT
    CACTATCACTACATTCCCAAAAGCGATTTATCTGCTAGTGAATTAGCAGCAGCTAAAGCA
    CATCTGGCTGGAAAAAATATGCAACCGAGTCAGTTAAGCTATTCTTCAACAGCTAGTGAC
    AATAACACGCAATCTGTAGCAAAAGGATCAATTAGCAAGCCAGCAAATAAATCTGAAAAT
    CTCCAGAGTCTTTTGAAGGAACTCTATGATTCACCTAGCGCCCAACGTTACAGTGAATCA
    GATGGCCTGGTCTTTGACCCTGCTAAGATTATCAGTCGTACACCAAATGGAGTTGCGATT
    CCGCATGGCGACCATTACCACTTTATTCCTTACAGCAAGCTTTCTGCCTTAGAAGAAAAG
    ATTGCCAGAATGGTGCCTATCAGTGGAACTGGTTCTACAGTTTCTACAAATGCAAAACCT
    AATGAAGTAGTGTCTAGTCTAGGCAGTCTTTCAAGCAATCCTTCTTCTTTAACGACAAGT
    AAGGAGCTCTCTTCAGCATCTGATGGTTATATTTTTAATCCAAAAGATATCGTTGAAGAA
    ACGGCTACAGCTTATATTGTAAGACATGGTGATCATTTCCATTACATTCCAAAATCAAAT
    CAAATTGGGCAACCGACTCTTCCAAACAATAGTCTAGCAACACCTTCTCCATCTCTTCCA
    ATCAATCCAGGAACTTCACATGAGAAACATGAAGAAGATGGATACGGATTTGATGCTAAT
    CGTATTATCGCTGAAGATGAATCAGGTTTTGTCATGAGTCACGGAGACCACAATCATTAT
    TTCTTCAAGAAGGACTTGACAGAAGAGCAAATTAAGGCTGCGCAAAAACATTTAGAGGAA
    GTTAAAACTAGTCATAATGGATTAGATTCTTTGTCATCTCATGAACAGGATTATCCAAGT
    AATGCCAAAGAAATGAAAGATTTAGATAAAAAAATCGAAGAAAAAATTGCTGGCATTATG
    AAACAATATGGTGTCAAACGTGAAAGTATTGTCGTGAATAAAGAAAAAAATGCGATTATT
    TATCCGCATGGAGATCACCATCATGCAGATCCGATTGATGAACATAAACCGGTTGGAATT
    GGTCATTCTCACAGTAACTATGAACTGTTTAAACCCGAAGAAGGAGTTGCTAAAAAAGAA
    GGGAATAAAGTTTATACTGGAGAAGAATTAACGAATGTTGTTAATTTGTTAAAAAATAGT
    ACGTTTAATAATCAAAACTTTACTCTAGCCAATGGTCAAAAACGCGTTTCTTTTAGTTTT
    CCGCCTGAATTGGAGAAAAAATTAGGTATCAATATGCTAGTAAAATTAATAACACCAGAT
    GGAAAAGTATTGGAGAAAGTATCTGGTAAAGTATTTGGAGAAGGAGTAGGGAATATTGCA
    AACTTTGAATTAGATCAACCTTATTTACCAGGACAAACATTTAAGTATACTATCGCTTCA
    AAAGATTATCCAGAAGTAAGTTATGATGGTACATTTACAGTTCCAACCTCTTTAGCTTAC
    AAAATGGCCAGTCAAACGATTTTCTATCCTTTCCATGCAGGGGATACTTATTTAAGAGTG
    AACCCTCAATTTGCAGTGCCTAAAGGAACTGATGCTTTAGTCAGAGTGTTTGATGAATTT
    CATGGAAATGCTTATTTAGAAAATAACTATAAAGTTGGTGAAATCAAATTACCGATTCCG
    AAATTAAACCAAGGAACAACCAGAACGGCCGGAAATAAAATTCCTGTAACCTTCATGGCA
    AATGCTTATTTGGACAATCAATCGACTTATATTGTGGAAGTACCTATCTTGGAAAAAGAA
    AATCAAACTGATAAACCAAGTATTCTACCACAATTTAAAAGGAATAAAGCACAAGAAAAC
    TCAAAACTTGATGAAAAGGTAGAAGAACCAAAGACTAGTGAGAAGGTAGAAAAAGAAAAA
    CTTTCTGAAACTGGGAATAGTACTAGTAATTCAACGTTAGAAGAAGTTCCTACAGTGGAT
    CCTGTACAAGAAAAAGTAGCAAAATTTGCTGAAAGTTATGGGATGAAGCTAGAAAATGTC
    TTGTTTAATATGGACGGAACAATTGAATTATATTTACCATCGGGAGAAGTCATTAAAAAG
    AATATGGCAGATTTTACAGGAGAAGCACCTCAAGGAAATGGTGAAAATAAACCATCTGAA
    AATGGAAAAGTATCTACTGGAACAGTTGAGAACCAACCAACAGAAAATAAACCAGCAGAT
    TCTTTACCAGAGGCACCAAACGAAAAACCTGTAAAACCAGAAAACTCAACGGATAATGGA
    ATGTTGAATCCAGAAAGGAATGTGGGGAGTGACCCTATGTTAGATCCAGCATTAGAGGAA
    GCTCCAGCAGTAGATCCTGTACAAGAAAAATTAGAAAAATTTACAGCTAGTTACGGATTA
    GGCTTAGATAGTGTTATATTCAATATGGATGGAACGATTGAATTAAGATTGCCAAGTGGA
    GAAGTGATAAAAAAGAATTTATCTGATCTCATAGCGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
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    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3099

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EF3030_04840 [new locus tag: EF3030_RS04840 ]
  • symbol: PhtE
  • description: pneumococcal histidine triad protein PhtE
  • length: 1032
  • theoretical pI: 5.42506
  • theoretical MW: 113821
  • GRAVY: -0.674031

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Pathogenesis streptococcal histidine triad protein (TIGR01363; HMM-score: 553.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Strep_his_triad; Streptococcal histidine triad protein (PF04270; HMM-score: 269.7)
    and 3 more
    PH (CL0266) YcxB; YcxB-like protein (PF14317; HMM-score: 20.4)
    no clan defined PHtD_u1; Unstructured region on Pneumococcal histidine triad protein (PF16645; HMM-score: 16.5)
    CDA (CL0109) DddA-like; Double-stranded DNA deaminase toxin A (PF14428; HMM-score: 13.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.301979
    • TAT(Tat/SPI): 0.006574
    • LIPO(Sec/SPII): 0.327998
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QBF68884 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDGSQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSEELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEHVKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLSASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSISKPANKSENLQSLLKELYDSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPISGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAYIVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRIIAEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSNAKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVGIGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVSFSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFKYTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDALVRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYIVEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTSNSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTGEAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPERNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVIKKNLSDLIA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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