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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_1202 [new locus tag: SP670_RS05930 ]
  • pan locus tag?: PNEUPAN002294000
  • symbol: SP670_1202
  • pan gene symbol?: zmpA
  • synonym: iga
  • product: immunoglobulin A1 protease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP670_1202 [new locus tag: SP670_RS05930 ]
  • symbol: SP670_1202
  • product: immunoglobulin A1 protease
  • replicon: chromosome
  • strand: -
  • coordinates: 1120798..1126689
  • length: 5892
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    5761
    5821
    5881
    ATGGAAAAGTATTTTGGTGAAAAACAAGAGCGTTTTTCATTTAGAAAATTATCAGTAGGA
    CTTGTATCTGCAACGATTTCAAGTTTATTTTTTATGTCTGTATTAGCTAGTTCATCTGTG
    GATGCTCAAGAAACTGCGGGAGTTCACTATAAATATGTGGCAGATTCAGAGCTATCATCA
    GAAGAAAAGAAGCAGCTTGTCTATGATATTCCGACATACGTGGAGAATGATGATGAAACT
    TATTATCTTGTTTATAAGTTAAATTCTCAAAATCAACTGGCGGAATTACCAAATACTGGA
    AGCAAGAATGAGAGGCAAGCCCTAGTTGCTGGAGCTAGCTTAGCTGCTCTGGGAATTTTA
    ATTTTTGCTGTTTCCAAGAAAAAGGTTAAGAATAAAACGGTATTACATTTAGTATTGGTT
    GCGGGAATAGGAAATGGTGTCTTAGTTTCAGTCCATGCTTTAGAAAATCATCTTTTGCTA
    AATTACAATACGGACTATGAATTGACCTCTGGAGAAAAATTACCTCTTCCTAAAGAGATT
    TCAGGTTACACTTATATTGGATATATCAAAGAGGGAAAAACGACTTCTGATTTTGAAGTA
    AGTAATCAAGAAAAATCAGCAGCCACTCCTACAAAACAACAAAAGGTGGATTATAATGTT
    ACACCAAATTTTGTAGACCATCCATCAACAGTACAAGCTATTCAGGAACAAACACCTGTT
    TCTTCAACTAAGCCGACAGAAGTTCAAGTAGTTGAAAAACCTTTCTCTACTGAATTAATC
    AATCCAAGAAAAGAAGAGAAACAATCTTCAGATTCTCAAGAACAATTAGCCGAACATAAG
    AATCTAGAAACGAAGAAAGAGGAGAAGATTTCTCCAAAAGAAAAGACTGGGGTAAATACA
    TTAAATCCACAGGATGAAGTTTTATCAGGTCAATTGAACAAACCTGAACTCTTATATCGT
    GAGGAAACTATAGAGATAAAAATAGATTTTCAAGAAGAAATTCAAGAAAATCCTGATTTA
    GTTGAAGGAATTGTAAGAGTAAAACAAGAAGGTAAATTAGGTAAGAAAGTTGAAATCGTC
    AGAATATTCTCTGTAAACAAGGAAGAAGTTTCGCGAGAAATTGTTTCAACTTCAACGACT
    GCGCCTATTCCAAGAATAGTCGAAAAAGGTACTAAAAAAACTCAAGTTATAAAGGAACAA
    CCTGAGACTGGTGTAGAACATAAGGACGTACAGTCTGGAGCTATTGTTGAACCCGCAATT
    CAGCCTGAGTTGCCCGAAGCTGTAGTAAGTGACAAAGGCGTACCAGAAGTTCAACCAGCG
    TTGTCCAAAGCAGTTATAACCGACAAAGGTGAGACTGAGGTTCAACCAGAGTCGCCAGAT
    ACTGTGGTAAGTGATAAAGGTGAACCTGAACAGGTAGCACCGCTTCCAGAATATAAGGGT
    AATATTGAGCAAGTAAAACCTGAAACTCCGGTTGAGAAGACCAAAGAACAAGGTCCAGAA
    AAAACTGAAGAAGTTCCAGTAAAACCAACAGAAGAAACACCAGTAAATCCAAATGAAGGT
    ACTACAGAAGGAACCTCAATTCAAGAAGCAGAAAATCCAGTTCAACCTGCAGAAGAATCA
    ACAACGAATTCAGAGAAAGTATCACCAGATACATCTAGCGAAAATACTGGGGAAGAGTCC
    AGTAATCCTAGTGATTCGACAACCTCAGTTGGAGAATCAAATAAACCAGAACATAATGAC
    TCTAAAAATGAAAATTCAGAAAAAACTGTAGAAGAAGTTCCAGTAAATCCAAATGAAGGC
    ACAGTAGAAGGTACCTCAAATCAAGAAACAGAAAAACCAGTTCAACCTGCAGAAGAAACA
    CAAACAAACTCTGGGAAAATAGCTAACGAAAATACTGGAGAAGTATCCAATAAACCTAGT
    GATTCAAAACCACCAGTTGAAGAATCAAATCAACCAGAAAAAAACGGAACTGCAACAAAA
    CCAGAAAATTCAGGTAATACAACATCAGAGAATGGACAAACAGAACCAGAGAAAAAACTC
    GAATTAAGAAATGTTTCTGATATTGAGTTGTATAGTCAGACGAATGGAACCTACAGACAA
    CATGTTTCATTGGATGGAATTCCAGAGAATACGGATACTTACTTTGTCAAGGTAAAATCT
    TCAGCATTTAAAGATGTCTATATACCAGTAGCTTCAATAACTGAAGAGAAAAGAAATGGG
    CAGTCAGTTTATAAAATCACAGCCAAAGCTGAGAAACTCCAGCAAGAACTAGAAAATAAA
    TATGTCGACAATTTCACCTTCTACCTCGATAAGAAGGCTAAAGAGGAAAATACAAACTTT
    ACTTCCTTTAGCAACCTGGTCAAAGCTATAAACCAAAATCCCTCTGGAACCTATCATTTA
    GCGGCCAGCCTGAATGCTAACGAAGTGGAGCTTAGTACTGATGATAAATCCTATATCAAG
    GGAACCTTTACTGGTCAGTTGATTGGTGAAAAAGATGGTAAGCATTATGCTATTTACAAC
    TTGAAAAAGCCTCTTTTTGAAAACTTGAGTGGTGCTACAGTAGAAAAACTGAGTCTAAAA
    AATGTTGCTATTTCAGGGAAAAATGATATTGGTTCACTGGCAAATGAAGCTACGAATGGC
    ACAAAGATTAAACAAGTTCATGTTGATGGTGTTCTGGCTGGAGAACGTGGTGTCGGTGGT
    TTGTTGGCTAAGGCAGACCAATCAAGCATCGCAGAGAGCAGTTTCAAGGGAAGAATTGTC
    AATACCTATGAAACGACTGATTCCTACAATATTGGCGGTCTGGTCGGTCATTTAACAGGA
    AAAAATGCGTCTATTGCTAAATCCAAAGCGACAGTAACCATTTCGTCAAACACCAATAGG
    TCAGATCAGACTGTCGGTGGTCTTGCAGGTCTAGTAGACCGAGACGCACAGATCCAAGAT
    AGCTATGCTGAAGGTGATATCAACAATGTCAAGCACTTTGGTAGAGTCGCTGGAGTGGCA
    GGCAATTTGTGGGATCGAACTTCTGGTGATGTTAGGCATGCTGGAAGTTTGACCAATGTT
    CTCAGCGATGTTAATGTAACAAACGGAAATGCCATCACTGGATACCACTATACAGGAATG
    AAGGTAGCTAATACATTTAGTAGTAAGGCTAATAGAGTTTTCAATGTCACTTTAGAGAAG
    GATGAGGTCGTCAGCAAGGAATCCTTTGAAGAAAGAGGAACAATGCTAGATGCTTCTCAA
    ATTGTAAGCAAAAAAGCAGAAATAAGTCCTCTCACTCTACCAACGGTGGAACCCCTCTCA
    ACAAGTGGCAAGAAAGACAGTGATTTTTCTAAGATAGCCCATTATCAAGCTAACCGTGCT
    TTGGTTTATAAGAACATTGAAAAATTGTTACCTTTTTATAATAAGTCAACCATCGTGAAA
    TACGGAAACCTGGTTAAGGAGAACAGTCTCTTATACCAAAAAGAACTCTTATCTGCAGTT
    ATGATGAAGGATGACCAAGTAATCACAGATATTGTTTCCAACAAACAGACTGCAAACAAA
    CTCTTACTTCACTATAATGACCATTCATCTGAGAAATTTGATCTCAAGTACCAGACTGAT
    TTTGCCAATCTAGCAGAATATAATCTAGGTAATACGGGACTTCTCTACACTCCTAACCAA
    TTCTTATATGATCGAGACTCTATTGTTAAGGAAGTCTTGCCTGAGTTGCAGAAGCTTGAT
    TACCAGTCAGATGCTATCAGAAAGACACTTGGTATTTCTCCAGCAGTTAAGTTAACCGAG
    CTCTATTTAGAAGAGCAGTTCTCCAAAACAAAACAAAATCTGGGAGGCAGCTTGAAAAAA
    CTTTTGTCAGCAGATGCCGGTCTAGCTAGCGATAACTCAGTCACCAGAGGCTATCTTGTA
    GATAAAATCAAGAATAATAAGGAAGCCTTGCTACTCGGTTTAACTTATTTAGAACGTTGG
    TATAACTTTAACTATGGTCAAGTGAATGTCAAAGACCTAGTTATGTATCATCCAGACTTC
    TTTGGTAAAGGAAATACTTCCCCACTAGATACTCTGATTGAGTTAGGTAAATCTGGCTTT
    AACAATCTTCTTGCCAAGAACAATGTCGATACTTATGGTATCAGTCTAGCCAGCCATCAT
    GGAACGACAGATTTGTTTAGCGCACTTGAAACTTACCGAAAAGTCTTTTTACCAAACACT
    AGCAACAATGACTGGTTTAAAAAACAGACCAAAGCTTTCATTGTCGAAGAAAAATCCACT
    ATTGCAGAGGTCAAAGCCAAGCAAAAGCAAGCAGGAACTAAGTACTCTATCGGTGTTTAT
    GACCGAATTACTAGTAATACTTGGAAGTACCGGAATATGGTCTTGCCTCTCCTTACCTTG
    CCAGAAAGATCTGTATTTGTCATCTCAACCTTGTCTAGTCTAGGATTTGGTGCTTACGAT
    CGCTACCGTAATAGTGAACATAAAGCAGGCAAGGACCTCAATAATTTCGTTGAAGAAAAT
    GCGAGTGAAACTGCCAAACGTCAGCGAGATCACTACGATTATTGGTATCGCATTTTAGAT
    AATGAGGGACGTGAAAAACTATATCGTACGATTCTCCTTTATGATGCCTATAAGTTTGGT
    GATGACACAACATCTGGAAAAGCTACAGTGGAGGCTAAGTTTGATAGCTCCAATCCAGCC
    ATGAAGAATTTCTTTGGTCCAGTTGGTAATAAGGTTGTTCATAATCATCACGGTGCCTAC
    GCAACAGGAGATGGTGTCTACTATATGTCTTACCGCATGCTCGACAAGGATGGAGCCATT
    ACCTATACCCATGAGATGACCCATGATTCGGATCAAGATATTTACCTTGGCGGCTATGGT
    CGAAGAAGTGGTCTTGGTCCTGAGTTCTTTGCTAAAGGTTTATTACAAGCGCCAGACCAT
    CCATATGATGCGACCATTACCATTAACTCTATCTTGAAACATTCAAAATCAGATAGCTTA
    GAAGGATCGCGTCTGCAAGTCTTGGATCCGACAGAAAGATTCCAAAACTCAGCAGATCTT
    CAAAACTATGTTCACAACATGTTTGACCTCATCTATATGTTGGAATATCTAGAAGGGCAA
    TCGATTGTTAAGAAACTGAATGTTTCTCAGAAAATGGAAGCTCTCAGAAAAATCGAGAAT
    CAATATCTAACAGATCCTGCTGATGGAAATGAGGTTTACGCTACTAACGTAGTCAAAGAA
    TTGACAGAAGAAGAGGCCCGAAACCTGAATAGTTTTGATAGTTTGATTGACAATAATATT
    CTTTCAGCTCGTGAGTATAAGGCTGGTACATATGAGAGAAATGGCTACTTTACTATAAAA
    CTCTTTGCACCAATCTTTTCAGCATTGAGCAGTGAGAAAGGTACTCCTGGAGATCTTATG
    GGACGAAGGATAGCTTATGAACTCTTAGCTGCTAAAGGATTTAAAGATGGTATGGTACCA
    TATATTTCCAACCAATATGAAGGAATTGCTAAACAAAATGGTCAGACAATCAACCTTTAC
    GGTAAAAAGCAAGGATTAGTGACAGATAAGCTTGTTTTGGAAAAGATATTCTCTGGCAAG
    TATCCATCTTGGACAGCCTTTAAAAAAGCTATGTATCAAGAGCGTATTGCTCAGTTTGAT
    CATTTGACTAAAGTTATTTTTAAAGATCCGACAAAACCATGGCCAAGCTATGGCACAAAG
    ACTATCAATAATGTGGATGAATTGCAAGCCCTCATGGACCAAGCTGTTCTCAAGGATGCT
    GAAGGTCCACGTTGGAGTAATTATAATCCAGAAATCGACAGTGCCGTTCATAAGTTGAAG
    AGAGCAATCTTTAAAGCCTATCTTGACCAAACAAATGATTTTAGAAGTTCAATTTTTGAG
    AATAAAAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
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    1140
    1200
    1260
    1320
    1380
    1440
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    1560
    1620
    1680
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    1920
    1980
    2040
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    2160
    2220
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    2340
    2400
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    2520
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    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4320
    4380
    4440
    4500
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    4620
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    4920
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    5100
    5160
    5220
    5280
    5340
    5400
    5460
    5520
    5580
    5640
    5700
    5760
    5820
    5880
    5892

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP670_1202 [new locus tag: SP670_RS05930 ]
  • symbol: SP670_1202
  • description: immunoglobulin A1 protease
  • length: 1963
  • theoretical pI: 5.30763
  • theoretical MW: 218283
  • GRAVY: -0.643607

⊟Function[edit | edit source]

  • TIGRFAM:
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 43.3)
    and 1 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 21.9)
  • TheSEED  :
    • IgA-specific metalloendopeptidase (EC 3.4.24.13)
  • PFAM:
    no clan defined Peptidase_M26_C; M26 IgA1-specific Metallo-endopeptidase C-terminal region (PF07580; HMM-score: 1090)
    and 5 more
    Peptidase_M26_N; M26 IgA1-specific Metallo-endopeptidase N-terminal region (PF05342; HMM-score: 274.8)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 50.8)
    no clan defined Glug; The GLUG motif (PF07581; HMM-score: 43.8)
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 36)
    Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 29.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 2
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.0051
    • Cell wall & surface Score: 0.844
    • Extracellular Score: 0.1508
  • SignalP: Signal peptide SP(Sec/SPI) length 42 aa
    • SP(Sec/SPI): 0.91723
    • TAT(Tat/SPI): 0.067255
    • LIPO(Sec/SPII): 0.005174
    • Cleavage Site: CS pos: 42-43. VDA-QE. Pr: 0.9143
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM91265 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIEIKIDFQEEIQENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTKKTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKGETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEESSNPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLELRNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNGQSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTYHLAASLNANEVELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESSFKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLVDRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEISPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVKENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANLAEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPAVKLTELYLEEQFSKTKQNLGGSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERWYNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLASHHGTTDLFSALETYRKVFLPNTSNNDWFKKQTKAFIVEEKSTIAEVKAKQKQAGTKYSIGVYDRITSNTWKYRNMVLPLLTLPERSVFVISTLSSLGFGAYDRYRNSEHKAGKDLNNFVEENASETAKRQRDHYDYWYRILDNEGREKLYRTILLYDAYKFGDDTTSGKATVEAKFDSSNPAMKNFFGPVGNKVVHNHHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPYDATITINSILKHSKSDSLEGSRLQVLDPTERFQNSADLQNYVHNMFDLIYMLEYLEGQSIVKKLNVSQKMEALRKIENQYLTDPADGNEVYATNVVKELTEEEARNLNSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEGIAKQNGQTINLYGKKQGLVTDKLVLEKIFSGKYPSWTAFKKAMYQERIAQFDHLTKVIFKDPTKPWPSYGTKTINNVDELQALMDQAVLKDAEGPRWSNYNPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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