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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 15-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_RS14780 [old locus tag: SP670_2336 ]
  • pan locus tag?: PNEUPAN003887000
  • symbol: SP670_RS14780
  • pan gene symbol?: pspC
  • synonym: cbpA
  • product: RICH domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP670_RS14780 [old locus tag: SP670_2336 ]
  • symbol: SP670_RS14780
  • product: RICH domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2189909..2192707
  • length: 2799
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014498 (2189909..2192707) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_2017 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    ATGTTTGCATCAAAAAGCGAAAGAAAAGTACATTATTCAATTCGTAAATTTAGTATTGGA
    GTAGCTAGTGTAGTAGTTGCTAGTCTTGTTATGGGAAGTGTGGTTCATGCGACGGAGAAT
    GAGGGAATTACCCAAGTAGCCACTTCTTATAATAAGGCAAATGAAAGTCAGACAGAACAT
    AGGAAAGCTGCTAAACAAGTCGATGAAGATATAAAAAAAATGTTGAGTGAGATCCAAGAA
    TATATAAAAAAAATGTTGAGTGAGATCCAATTAGATAAAAGAAAAGATACCCAAAATCGC
    ACCTTAAACAGAAAGTTGAGCGCAATTCAAACGAAGTATTTGTATGAATTAAGAGTTTTA
    AAAGAGAAGTCGAAAAAAGAAGAGTTGACGTCAAAAACAAAAAAAGAGTTAGACGCAGCT
    TTTGAGAAGTTTAAAAAAGAACCAGAACTTACTAAAAAATTAGCAGAAGCTAAACAAAAA
    GCCAAGGCTCAAAAAGAAGAAGATTTCCGTAACTACCCAACCAATACTTACAAAACGCTT
    GAACTTGAAATTGCTGAGTTCGATGTGAAAGTTAAAGAAGCGGAGCTTGAACTAGTAAAA
    GAGGAAGCTAAACCCCGAAACGAGGAAAAAATTAAGCAAGCAAAAGCGAAAGTTGAGAGT
    AAAAAAGCTGAGGCTACAAGGTTAGAAGAAATCAAGACAGAACGTAAAAAAGCAGAAGAA
    GAAGCTAAACGAAAAGCAGAAGAATCTGAGAAAAAAGCTGCTGAAGCCAAACAAAAAGTG
    GATACTAAAGAGCAAGGTAAACCAAAGAGGCGGGCAAAACGAGGAGTTTCTGGAGAGCTA
    GCAACACCTGATAAAAAAGAAAATGATGCGAAGTCTTCAGATTCTAGCGTAGGTGAAGAA
    ACTCTTCCAAGCCCATCCCTTAATATGGCAAATGAAAGTCAGACAGAACATAGGAAAGAT
    GTCGATGAATATATAAAAAAAATGTTGAGTGAGATCCAATTAGATAGAAGAAAACATACC
    CAAAATGTCAACTTAAACATAAAGTTGAGCGCAATTAAAACGAAGTATTTGTATGAATTA
    AGTGTTTTAAAAGAGAACTCGAAAAAAGAAGAGTTGACGTCAAAAACCAAAGCAGAGTTA
    ACCGCAGCTTTTGAGCAGTTTAAAAAAGATACATTGAAACCAGAAAAAAAGGTAGCAGAA
    GCTGAGAAGAAGGTTGAAGAAGCTAAGAAAAAAGCCAAGGATCAAAAAGAAGAAGATCGC
    CGTAACTACCCAACCAATACTTACAAAACGCTTGAACTTGAAATTGCTGAGTCCGATGTG
    AAAGTTAAAGAAGCGGAGCTTGAACTAGTAAAAGAGGAAGCTAACGAATCTCGAAACGAG
    GAAAAAATTAAGCAAGCAAAAGAGAAAGTTGAGAGTAAAAAAGCTGAGGCTACAAGGTTA
    GAAAAAATCAAGACAGATCGTAAAAAAGCAGAAGAAGAAGCTAAACGAAAAGCAGAAGAA
    TCTGAGAAAAAAGCTGCTGAAGCCAAACAAAAAGTGGATGCTGAAGAATATGCTCTTGAA
    GCTAAAATCGCTGAGTTGGAATATGAAGTTCAGAGACTAGAAAAAGAGCTCAAAGAGATT
    GATGAGTCTGACTCAGAAGATTATCTTAAAGAAGGCCTCCGTGCTCCTCTTCAATCTAAA
    TTGGATACCAAAAAAGCTAAACTATCAAAACTTGAAGAGTTGAGTGATAAGATTGATGAG
    TTAGACGCTGAAATTGCAAAACTTGAAGTTCAACTTAAAGATGCTGAAGGAAACAATAAT
    GTAGAAGCCTACTTTAAAGAAGGTTTAGAGAAAACTACTGCTGAGAAAAAAGCTGAATTA
    GAAAAAGCTGAAGCTGACCTTAAGAAAGCAGTTGATGAGCCAGAAACTCCAGCTCCGGCT
    CCTCAACCAGCTCCAGCTCCAGAAAAACCAGCTCCAGCTCCAGAAAAACCAGCTGAAAAA
    CCAGCTCCAGCTCCAGCTCCAGAAAAACCAGCTCCAGCTCCAGAAAAACCAGCTCCAGCT
    CCAGAAAAACCAGCTCCAGCTCCAGAAAAACCAGCTCCAACTCCAGAAAAACCAGCTCCA
    GCTCCAGAAAAACCAGCTCCAACTCCAGAAACTCCAAAAACAGGCTGGAAACAAGAAAAC
    GGTATGTGGTACTTCTACAATACTGATGGTTCAATGGCAACAGGCTGGCTCCAAAACAAT
    GGCTCATGGTACTACCTCAACAGCAATGGCGCTATGGCGACAGGATGGCTCCAAAACAAT
    GGCTCATGGTACTACCTCAACAGCAATGGCGCTATGGCGACAGGATGGCTCCAATACAAT
    GGTTCATGGTACTACCTCAACGCTAATGGTGATATGGCGACAGGATGGTTCCAATACAAT
    GGTTCATGGTACTACCTCAACGCTAATGGTGATATGGCGACAGGATGGTTCCAATACAAT
    GGTTCATGGTACTACCTCAACGCTAATGGTGATATGGCGACAGGATGGTTCCAATACAAT
    GGTTCATGGTACTACCTCAACGCTAATGGTGATATGGCGACAGGATGGCTCCAATACAAT
    GGTTCATGGTACTACCTAAACGCTAACGGTTCAATGGCAACAGATTGGGTGAAAGATGGA
    GATACCTGGTACTATCTTGAAGCATCAGGTGCTATGAAAGCAAGCCAATGGTTCAAAGTA
    TCAGATAAATGGTACTATGTCAATGGCTCAGGTGCCCTTGCAGTCAACACAACTGTAGAT
    AGCTATAGAGTCAATGCCAATGGTGAATGGGTAAACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2799

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP670_RS14780 [old locus tag: SP670_2336 ]
  • symbol: SP670_RS14780
  • description: RICH domain-containing protein
  • length: 932
  • theoretical pI: 6.30005
  • theoretical MW: 105809
  • GRAVY: -1.072

⊟Function[edit | edit source]

  • TIGRFAM:
    glucan-binding repeat (TIGR04035; HMM-score: 58.3)
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 52.7)
    and 2 more
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 5.3)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 5.3)
  • TheSEED: see SP670_2336
  • PFAM:
    Choline_binding (CL0694) Choline_bind_3; Choline-binding repeat (PF19127; HMM-score: 203.3)
    Choline_bind_1; Putative cell wall binding repeat (PF01473; HMM-score: 188.6)
    no clan defined RICH; RICH domain (PF05062; HMM-score: 171.6)
    and 5 more
    Choline_binding (CL0694) Choline_bind_2; Choline-binding repeat (PF19085; HMM-score: 47.4)
    no clan defined YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 40.6)
    DUF1192; Protein of unknown function (DUF1192) (PF06698; HMM-score: 13.8)
    HSBP1; Heat shock factor binding protein 1 (PF06825; HMM-score: 13.3)
    NinB; NinB protein (PF05772; HMM-score: 10)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.1
    • Cytoplasmic Membrane Score: 0.14
    • Cellwall Score: 0.15
    • Extracellular Score: 9.6
    • Internal Helices: 0
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.978861
    • TAT(Tat/SPI): 0.013561
    • LIPO(Sec/SPII): 0.001835
    • Cleavage Site: CS pos: 37-38. VHA-TE. Pr: 0.9616
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000458173 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGITQVATSYNKANESQTEHRKAAKQVDEDIKKMLSEIQEYIKKMLSEIQLDKRKDTQNRTLNRKLSAIQTKYLYELRVLKEKSKKEELTSKTKKELDAAFEKFKKEPELTKKLAEAKQKAKAQKEEDFRNYPTNTYKTLELEIAEFDVKVKEAELELVKEEAKPRNEEKIKQAKAKVESKKAEATRLEEIKTERKKAEEEAKRKAEESEKKAAEAKQKVDTKEQGKPKRRAKRGVSGELATPDKKENDAKSSDSSVGEETLPSPSLNMANESQTEHRKDVDEYIKKMLSEIQLDRRKHTQNVNLNIKLSAIKTKYLYELSVLKENSKKEELTSKTKAELTAAFEQFKKDTLKPEKKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELVKEEANESRNEEKIKQAKEKVESKKAEATRLEKIKTDRKKAEEEAKRKAEESEKKAAEAKQKVDAEEYALEAKIAELEYEVQRLEKELKEIDESDSEDYLKEGLRAPLQSKLDTKKAKLSKLEELSDKIDELDAEIAKLEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAEADLKKAVDEPETPAPAPQPAPAPEKPAPAPEKPAEKPAPAPAPEKPAPAPEKPAPAPEKPAPAPEKPAPTPEKPAPAPEKPAPTPETPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNSNGAMATGWLQYNGSWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWLQYNGSWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDSYRVNANGEWVN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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