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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_1378 [new locus tag: SP_RS06755 ]
  • pan locus tag?: PNEUPAN002654000
  • symbol: SP_1378
  • pan gene symbol?: ywbD
  • synonym:
  • product: conserved hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_1378 [new locus tag: SP_RS06755 ]
  • symbol: SP_1378
  • product: conserved hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1300390..1301562
  • length: 1173
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGTAGTTATGAATAGAATAAGAGTCAGCAAAAGGGTTGAAAAGAAGCTTGCTAAGGGG
    CTAGTTTTACTAGAAGCCAGTGATCTTGAGAATGTCAATCTTAAGGATCAGGAAGTAGAG
    GTGCAGGGTCAGGAAGGAAACTTTCTTGGGACTGCCTACCTTTCTCAGCAAAACAAGGGC
    TTGGGCTGGTTTATCAGCAAAGACAAGGTGGCCTTCAATCAAGCTTTCTTTGAAACGTTG
    TTTAGAAAAGCCAAAGAAAAGAGAAACGCCTACTATCAAGATGATTTGACAACTGCCTTT
    CGTCTCTTTAATCAAGAGGGAGATGGCTTTGGGGGTCTGACAGTGGACCTTTATGGCGAC
    TACGCCGTCTTTTCTTGGTATAACTCTTATGTTTATCAGATTCGTCAGACTATATCAGAA
    GCCTTTAGACAGGTTTTCCCTGAGGTTTTAGGAGCTTATGAGAAAATCCGCTTTAAGGGT
    TTGGACTATGAATCTGCCCATGTTTATGGTCAAGAAGCACCTGACTTTTTCAATGTTTTA
    GAAAATGGTGTCCTGTATCAAGTCTTTATGAATGATGGCTTGATGACAGGAATTTTCCTA
    GACCAGCATGAGGTTCGCGGTAGTTTAGTTGACGGCTTGGCTATGGGTAAATCCTTACTC
    AATATGTTTTCCTACACAGCGGCTTTTTCAGTAGCTGCGGCCATGGGAGGAGCTAGCCAT
    ACAACTTCTGTTGATCTAGCCAAACGTTCACGAGAATTGTCTCAAGCGCATTTTCAGGCA
    AATGGGCTCAGCACAGACGAGCATCGTTTTATAGTCATGGATGTCTTTGAGTATTTCAAA
    TATGCCAAACGCAAAGACTTGACCTACGATGTGATTGTCCTAGATCCGCCTAGCTTTGCT
    CGGAATAAAAAACAAACTTTCTCTGTGGCCAAGGATTATCACAAGTTGATTTCCCAGAGT
    CTTGAGATTTTAAATCCGGGAGGGATTATCATTGCCAGTACCAATGCTGCCAATGTTTCC
    CGTCAGAAATTTACAGAACAAATTGATAAAGGTTTTGCAGGAAGAAGTTACCAGATTTTA
    AACAAATATGGTCTTCCAGCAGATTTTGCCTATAATAAAAAAGATGAAAGTAGTAATTAC
    CTCAAGGTGATTAGTATGAAGGTTAGTAAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1173

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_1378 [new locus tag: SP_RS06755 ]
  • symbol: SP_1378
  • description: conserved hypothetical protein
  • length: 390
  • theoretical pI: 8.83197
  • theoretical MW: 44170.8
  • GRAVY: -0.297179

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD (TIGR00095; EC 2.1.1.171; HMM-score: 24.5)
    and 1 more
    Genetic information processing Protein fate Protein modification and repair protein-(glutamine-N5) methyltransferase, release factor-specific (TIGR03534; EC 2.1.1.-; HMM-score: 15.1)
  • TheSEED  :
    • LSU m5C1962 methyltransferase RlmI
    Protein Metabolism Protein biosynthesis Ribosome biogenesis bacterial  LSU m5C1962 methyltransferase RlmI
  • PFAM:
    NADP_Rossmann (CL0063) Methyltrans_SAM; S-adenosylmethionine-dependent methyltransferase (PF10672; HMM-score: 100.8)
    and 5 more
    PUA (CL0178) PUA_3; PUA-like domain (PF17785; HMM-score: 41)
    NADP_Rossmann (CL0063) Cons_hypoth95; Conserved hypothetical protein 95 (PF03602; HMM-score: 29.7)
    MTS; Methyltransferase small domain (PF05175; HMM-score: 24.2)
    Methyltransf_25; Methyltransferase domain (PF13649; HMM-score: 16.9)
    Methyltransf_24; Methyltransferase domain (PF13578; HMM-score: 13.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9814
    • Cytoplasmic Membrane Score: 0.0022
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.0154
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008949
    • TAT(Tat/SPI): 0.000165
    • LIPO(Sec/SPII): 0.001368
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MVVMNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGNFLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQEGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDYESAHVYGQEAPDFFNVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLNMFSYTAAFSVAAAMGGASHTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYFKYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAANVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ 1.0 1.1 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
    The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
    PLoS Pathog: 2018, 14(12);e1007461
    [PubMed:30517198] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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