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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-APR-2025

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ST556
  • locus tag: MYY_RS06765 [old locus tag: MYY_1320 ]
  • pan locus tag?: PNEUPAN001836000
  • symbol: MYY_RS06765
  • pan gene symbol?:
  • synonym:
  • product: DUF6556 family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: MYY_RS06765 [old locus tag: MYY_1320 ]
  • symbol: MYY_RS06765
  • product: DUF6556 family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1300038..1300466
  • length: 429
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_017769 (1300038..1300466) NCBI
  • BioCyc: MYY_RS06765 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0775 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGTCTAACTATCGTAGAACTTCAAAACCGAAAACAGAACATATCAAAAAAGGCTTTACT
    GTTTTTCAAAAAACCATTACTACTATCGGTAGTATCCTTGGTTTGATTACCGCGGGTATC
    ACGATCATGAACGCCTTGGATAATAATAAAAATACTAAAAAAGAACCTACGACAAGCCAG
    ACGACAACCTTTGTCAAAGAAATTCAAAAAGAATCCCCTCAGGAAAATACTACTCCAAAT
    AAGGAAAATAACACTTCTCAAGAAAAAACACAACAAGAAGAAACGCCAAAATCTAGCGTC
    AAGGAAGAGAAAAAAGAAGATCAGAAAACAGCAACTCAGGACTCTACTACACCTGCTACA
    AGTAAACCTGCCACTGAAAATGAAAAACAGCCCAATACTCCAACTTCAGAAAATAAAAGT
    AATCAATAA
    60
    120
    180
    240
    300
    360
    420
    429

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: MYY_RS06765 [old locus tag: MYY_1320 ]
  • symbol: MYY_RS06765
  • description: DUF6556 family protein
  • length: 142
  • theoretical pI: 9.97554
  • theoretical MW: 15847.4
  • GRAVY: -1.42113

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism TCA cycle dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex (TIGR01347; EC 2.3.1.61; HMM-score: 7)
    cobaltochelatase subunit (TIGR02442; EC 6.6.1.2; HMM-score: 6.8)
    pullulanase, extracellular (TIGR02102; HMM-score: 6.4)
    Cellular processes Cellular processes Pathogenesis putative immunoglobulin-blocking virulence protein (TIGR04526; HMM-score: 6.3)
  • TheSEED: see MYY_1320
  • PFAM:
    no clan defined DUF6556; Family of unknown function (DUF6556) (PF20193; HMM-score: 100.2)
    and 23 more
    VESA1_N; Variant erythrocyte surface antigen-1 (PF12785; HMM-score: 16.3)
    MFS (CL0015) BT1; BT1 family (PF03092; HMM-score: 13.9)
    no clan defined Pep1_7; Elicitor peptide 1-7 (PF17232; HMM-score: 13.8)
    Multiheme_cytos (CL0317) C_GCAxxG_C_C; Putative redox-active protein (C_GCAxxG_C_C) (PF09719; HMM-score: 12.7)
    no clan defined DUF3807; Protein of unknown function (DUF3807) (PF12720; HMM-score: 12.7)
    TrbC_VirB2 (CL0690) DUF4134; Domain of unknown function (DUF4134) (PF13572; HMM-score: 12.6)
    DMT (CL0184) Zip; ZIP Zinc transporter (PF02535; HMM-score: 12.5)
    no clan defined DUF5850; Family of unknown function (DUF5850) (PF19168; HMM-score: 11.4)
    vMSA; Major surface antigen from hepadnavirus (PF00695; HMM-score: 10.2)
    DUF5427; Family of unknown function (DUF5427) (PF10310; HMM-score: 8.5)
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region (PF02932; HMM-score: 8.1)
    GPCR_A (CL0192) SID-1_RNA_chan; dsRNA-gated channel SID-1 (PF13965; HMM-score: 8.1)
    no clan defined RR_TM4-6; Ryanodine Receptor TM 4-6 (PF06459; HMM-score: 8)
    CIS_TMP; Contractile injection system tape measure protein (PF19268; HMM-score: 7.4)
    Serinc; Serine incorporator (Serinc) (PF03348; HMM-score: 7)
    DDHD; DDHD domain (PF02862; HMM-score: 6.8)
    SLC12; Solute carrier family 12 (PF03522; HMM-score: 6.8)
    AhpD-like (CL0423) PA26; PA26 p53-induced protein (sestrin) (PF04636; HMM-score: 6.8)
    no clan defined Peroxin-13_N; Peroxin 13, N-terminal region (PF04088; HMM-score: 6.6)
    TPR (CL0020) Suf; Suppressor of forked protein (Suf) (PF05843; HMM-score: 6.5)
    Nucleocapsid (CL0156) Paramyxo_ncap; Paramyxovirus nucleocapsid protein (PF00973; HMM-score: 6.2)
    no clan defined Snu56_snRNP; Snu56-like U1 small nuclear ribonucleoprotein component (PF19097; HMM-score: 5.6)
    CDC45; CDC45-like protein (PF02724; HMM-score: 5.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0056
    • Cytoplasmic Membrane Score: 0.5505
    • Cell wall & surface Score: 0.2744
    • Extracellular Score: 0.1695
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.401477
    • TAT(Tat/SPI): 0.013666
    • LIPO(Sec/SPII): 0.020558
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000073927 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMNALDNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVKEEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENKSNQ

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]